tetano
Editor, Senior Moderator
Cureus
. 2024 Mar 12;16(3):e56064.
doi: 10.7759/cureus.56064. eCollection 2024 Mar. Miller-Fisher Syndrome Following Influenza A Infection
Shiho Mitsuhashi[SUP] 1 [/SUP], Asuka Suzuki[SUP] 1 [/SUP], Koji Hayashi[SUP] 1 [/SUP], Mamiko Sato[SUP] 1 [/SUP], Yuka Nakaya[SUP] 1 [/SUP], Naoko Takaku[SUP] 1 [/SUP], Yasutaka Kobayashi[SUP] 2 [/SUP]
Affiliations
Miller-Fisher syndrome (MFS), characterized by ophthalmoplegia, ataxia, and areflexia, is a Guillain-Barré syndrome (GBS) variant. It is well-known that the causative antibody for MFS is anti-GQ1b antibody. This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1a antibodies following Influenza A infection. The patient, a 47-year-old woman, contracted Influenza A three weeks before admission. She complained of double vision followed by areflexia, ataxia in the four extremities, and complete gaze palsy. She was treated with intravenous methylprednisolone pulse and intravenous immunoglobulin therapies. Her neurological symptoms were recovered after these immunotherapies.
Keywords: guillain-barre syndrome (gbs); influenza virus type a; intravenous immunoglobulins (ivig); methyl prednisolone; miller fisher syndrome (mfs).
. 2024 Mar 12;16(3):e56064.
doi: 10.7759/cureus.56064. eCollection 2024 Mar. Miller-Fisher Syndrome Following Influenza A Infection
Shiho Mitsuhashi[SUP] 1 [/SUP], Asuka Suzuki[SUP] 1 [/SUP], Koji Hayashi[SUP] 1 [/SUP], Mamiko Sato[SUP] 1 [/SUP], Yuka Nakaya[SUP] 1 [/SUP], Naoko Takaku[SUP] 1 [/SUP], Yasutaka Kobayashi[SUP] 2 [/SUP]
Affiliations
- PMID: 38618457
- PMCID: PMC11009552
- DOI: 10.7759/cureus.56064
Miller-Fisher syndrome (MFS), characterized by ophthalmoplegia, ataxia, and areflexia, is a Guillain-Barré syndrome (GBS) variant. It is well-known that the causative antibody for MFS is anti-GQ1b antibody. This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1a antibodies following Influenza A infection. The patient, a 47-year-old woman, contracted Influenza A three weeks before admission. She complained of double vision followed by areflexia, ataxia in the four extremities, and complete gaze palsy. She was treated with intravenous methylprednisolone pulse and intravenous immunoglobulin therapies. Her neurological symptoms were recovered after these immunotherapies.
Keywords: guillain-barre syndrome (gbs); influenza virus type a; intravenous immunoglobulins (ivig); methyl prednisolone; miller fisher syndrome (mfs).