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Cureus . Exploring the Correlation Between Influenza A Virus (H3N2) Infections and Neurological Manifestations: A Scoping Review

tetano

Editor, Senior Moderator
Cureus


. 2023 Mar 30;15(3):e36936.
doi: 10.7759/cureus.36936. eCollection 2023 Mar. Exploring the Correlation Between Influenza A Virus (H3N2) Infections and Neurological Manifestations: A Scoping Review

Mithun K Reddy[SUP] 1 [/SUP], Jayashankar Ca[SUP] 2 [/SUP], Venkataramana Kandi[SUP] 3 [/SUP], Pooja M Murthy[SUP] 1 [/SUP], Ganaraja V Harikrishna[SUP] 4 [/SUP], Snigdha Reddy[SUP] 5 [/SUP], Manish Gr[SUP] 5 [/SUP], Koshy Sam[SUP] 2 [/SUP], Sai Teja Challa[SUP] 5 [/SUP]



Affiliations
Free PMC article Abstract

Influenza A virus (IAV), particularly the H3N2 variant, is known to cause respiratory manifestations, but it can also lead to neurological complications ranging from mild symptoms like headache and dizziness to severe conditions such as encephalitis and acute necrotizing encephalopathy (ANE). In this article, the correlation between the H3N2 variant of the IAV and neurological manifestations is discussed. Additionally, prompt recognition and treatment of influenza-associated neurological manifestations are highlighted to prevent infection-related long-term complications. This review briefly discusses various neurological complications linked to IAV infections, such as encephalitis, febrile convulsions, and acute disseminated encephalomyelitis, and the potential mechanisms involved in the development of neurological complications.

Keywords: encephalitis; febrile convulsions; h3n2; influenza a virus; neurological manifestations.

 
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