tetano
Editor, Senior Moderator
Cureus
. 2023 Mar 13;15(3):e36093.
doi: 10.7759/cureus.36093. eCollection 2023 Mar.
Characteristics of Cardiac Abnormalities in Pediatric Patients With Acute COVID-19
Daniel Pasternack[SUP] 1 2 [/SUP], Rakesh K Singh[SUP] 1 2 [/SUP], Prashant K Minocha[SUP] 1 2 [/SUP], Jon S Farkas[SUP] 3 2 [/SUP], Prema Ramaswamy[SUP] 4 [/SUP], Donna Better[SUP] 5 6 [/SUP], Sourabh Verma[SUP] 7 2 [/SUP], Colin K Phoon[SUP] 1 2 [/SUP]
Affiliations
Abstract
Introduction Coronavirus disease 2019 (COVID-19) is known to cause cardiac abnormalities in adults. Cardiac abnormalities are well-described in multisystem inflammatory syndrome in children, but effects in children with acute COVID-19 are less understood. In this multicenter study, we assessed the cardiac effects of acute COVID-19 among hospitalized children (<21 years) admitted to three large healthcare systems in New York City. Methods We performed a retrospective observational study. We examined electrocardiograms, echocardiograms, troponin, or B-type natriuretic peptides. Results Of 317 admitted patients, 131 (41%) underwent cardiac testing with 56 (43%) demonstrating cardiac abnormalities. Electrocardiogram abnormalities were the most common (46/117 patients (39%)), including repolarization abnormalities and QT prolongation. Elevated troponin occurred in 14/77 (18%) patients and B-type natriuretic peptide in 8/39 (21%) patients. Ventricular dysfunction was identified in 5/27 (19%) patients with an echocardiogram, all of whom had elevated troponin. Ventricular dysfunction resolved by first outpatient follow-up. Conclusion Electrocardiogram and troponin can assist clinicians in identifying children at risk for cardiac injury in acute COVID-19.
Keywords: covid-19; electrocardiogram; myocarditis; pediatrics; ventricular dysfunction.
. 2023 Mar 13;15(3):e36093.
doi: 10.7759/cureus.36093. eCollection 2023 Mar.
Characteristics of Cardiac Abnormalities in Pediatric Patients With Acute COVID-19
Daniel Pasternack[SUP] 1 2 [/SUP], Rakesh K Singh[SUP] 1 2 [/SUP], Prashant K Minocha[SUP] 1 2 [/SUP], Jon S Farkas[SUP] 3 2 [/SUP], Prema Ramaswamy[SUP] 4 [/SUP], Donna Better[SUP] 5 6 [/SUP], Sourabh Verma[SUP] 7 2 [/SUP], Colin K Phoon[SUP] 1 2 [/SUP]
Affiliations
- PMID: 37065296
- PMCID: PMC10097430
- DOI: 10.7759/cureus.36093
Abstract
Introduction Coronavirus disease 2019 (COVID-19) is known to cause cardiac abnormalities in adults. Cardiac abnormalities are well-described in multisystem inflammatory syndrome in children, but effects in children with acute COVID-19 are less understood. In this multicenter study, we assessed the cardiac effects of acute COVID-19 among hospitalized children (<21 years) admitted to three large healthcare systems in New York City. Methods We performed a retrospective observational study. We examined electrocardiograms, echocardiograms, troponin, or B-type natriuretic peptides. Results Of 317 admitted patients, 131 (41%) underwent cardiac testing with 56 (43%) demonstrating cardiac abnormalities. Electrocardiogram abnormalities were the most common (46/117 patients (39%)), including repolarization abnormalities and QT prolongation. Elevated troponin occurred in 14/77 (18%) patients and B-type natriuretic peptide in 8/39 (21%) patients. Ventricular dysfunction was identified in 5/27 (19%) patients with an echocardiogram, all of whom had elevated troponin. Ventricular dysfunction resolved by first outpatient follow-up. Conclusion Electrocardiogram and troponin can assist clinicians in identifying children at risk for cardiac injury in acute COVID-19.
Keywords: covid-19; electrocardiogram; myocarditis; pediatrics; ventricular dysfunction.