tetano
Editor, Senior Moderator
Cureus
. 2022 Jun 20;14(6):e26111.
doi: 10.7759/cureus.26111. eCollection 2022 Jun.
Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Renal Vasculitis After COVID-19 Infection: A Case Report
Saurabh Kataria[SUP] 1 2 3 [/SUP], Sylvette Rogers[SUP] 4 [/SUP], Haleema Sadia[SUP] 5 [/SUP], Tooba Ali[SUP] 6 [/SUP], Hasham M Qureshi[SUP] 7 [/SUP], Shehar Bano[SUP] 8 [/SUP], Chinyere L Anigbo[SUP] 9 [/SUP], Romil Singh[SUP] 10 [/SUP]
Affiliations
Abstract
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a class of autoimmune diseases that can cause kidney failure because of mononuclear cell infiltration and the destruction of small and medium-sized blood vessels. Coronavirus disease 2019 (COVID-19) may trigger or exacerbate autoimmune diseases. We present a case of ANCA-associated vasculitis in a patient with rheumatoid arthritis after a COVID-19 infection, who presented with intermittent hemoptysis and dyspnea and was diagnosed with COVID-19 pneumonia three weeks ago. Her clinical, radiological, and serological picture was concerned with pulmonary-renal syndrome. Her serum was positive for antinuclear antibody and ANCAs, and renal biopsy showed pauci-immune crescentic glomerulonephritis. She was diagnosed clinicopathologically with pauci-immune glomerulonephritis in the setting of rheumatoid arthritis (RA) after a COVID-19 infection. Her condition improved after she was treated with rituximab and pulse dose methylprednisolone.
Keywords: anca associated vasculitis; antineutrophil cytoplasmic antibody (anca); coronavirus disease; covid-19; rheumatoid arthritis.
. 2022 Jun 20;14(6):e26111.
doi: 10.7759/cureus.26111. eCollection 2022 Jun.
Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Renal Vasculitis After COVID-19 Infection: A Case Report
Saurabh Kataria[SUP] 1 2 3 [/SUP], Sylvette Rogers[SUP] 4 [/SUP], Haleema Sadia[SUP] 5 [/SUP], Tooba Ali[SUP] 6 [/SUP], Hasham M Qureshi[SUP] 7 [/SUP], Shehar Bano[SUP] 8 [/SUP], Chinyere L Anigbo[SUP] 9 [/SUP], Romil Singh[SUP] 10 [/SUP]
Affiliations
- PMID: 35875289
- PMCID: PMC9298682
- DOI: 10.7759/cureus.26111
Abstract
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a class of autoimmune diseases that can cause kidney failure because of mononuclear cell infiltration and the destruction of small and medium-sized blood vessels. Coronavirus disease 2019 (COVID-19) may trigger or exacerbate autoimmune diseases. We present a case of ANCA-associated vasculitis in a patient with rheumatoid arthritis after a COVID-19 infection, who presented with intermittent hemoptysis and dyspnea and was diagnosed with COVID-19 pneumonia three weeks ago. Her clinical, radiological, and serological picture was concerned with pulmonary-renal syndrome. Her serum was positive for antinuclear antibody and ANCAs, and renal biopsy showed pauci-immune crescentic glomerulonephritis. She was diagnosed clinicopathologically with pauci-immune glomerulonephritis in the setting of rheumatoid arthritis (RA) after a COVID-19 infection. Her condition improved after she was treated with rituximab and pulse dose methylprednisolone.
Keywords: anca associated vasculitis; antineutrophil cytoplasmic antibody (anca); coronavirus disease; covid-19; rheumatoid arthritis.