tetano
Editor, Senior Moderator
Cureus
. 2022 Apr 10;14(4):e24017.
doi: 10.7759/cureus.24017. eCollection 2022 Apr.
Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
Younus Al-Midfai[SUP] 1 2 [/SUP], Winy Kujundzic[SUP] 1 2 [/SUP], Simrun Uppal[SUP] 3 [/SUP], Darby Oakes[SUP] 3 [/SUP], Sardinas Giezy[SUP] 1 [/SUP]
Affiliations
Abstract
Multiple sclerosis (MS) is a neurologic disease caused by a chronic autoimmune process resulting in the demyelination of axons within the central nervous system. MS occurs through combined genetic susceptibility and environmental triggers. MS relapses (MSR) are characterized by acute inflammatory reactions and symptoms. Here we present a novel case of MSR following the second dose of the Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccine (Johnson & Johnson, New Brunswick, New Jersey, United States), presenting with paresthesias and left foot deficit. Additional research and studies are necessary to explore the relationship of COVID-19 vaccinations with MSR.
Keywords: allergy and anaphylaxis; covid 19; covid-19 vaccination; infectious disease control; johnson & johnson; multiple sclerosis flare-ups; multiple sclerosis relapse.
. 2022 Apr 10;14(4):e24017.
doi: 10.7759/cureus.24017. eCollection 2022 Apr.
Acute Multiple Sclerosis Exacerbation After Vaccination With the Johnson & Johnson COVID-19 Vaccine: Novel Presentation and First Documented Case Report
Younus Al-Midfai[SUP] 1 2 [/SUP], Winy Kujundzic[SUP] 1 2 [/SUP], Simrun Uppal[SUP] 3 [/SUP], Darby Oakes[SUP] 3 [/SUP], Sardinas Giezy[SUP] 1 [/SUP]
Affiliations
- PMID: 35547449
- PMCID: PMC9090220
- DOI: 10.7759/cureus.24017
Abstract
Multiple sclerosis (MS) is a neurologic disease caused by a chronic autoimmune process resulting in the demyelination of axons within the central nervous system. MS occurs through combined genetic susceptibility and environmental triggers. MS relapses (MSR) are characterized by acute inflammatory reactions and symptoms. Here we present a novel case of MSR following the second dose of the Johnson & Johnson coronavirus disease 2019 (COVID-19) vaccine (Johnson & Johnson, New Brunswick, New Jersey, United States), presenting with paresthesias and left foot deficit. Additional research and studies are necessary to explore the relationship of COVID-19 vaccinations with MSR.
Keywords: allergy and anaphylaxis; covid 19; covid-19 vaccination; infectious disease control; johnson & johnson; multiple sclerosis flare-ups; multiple sclerosis relapse.