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Cureus . A Case of Coombs-Negative Hemolytic Anemia Prompting Diagnosis of SARS-CoV-2

tetano

tetano

Editor, Senior Moderator
Cureus


. 2021 Nov 30;13(11):e20034.
doi: 10.7759/cureus.20034. eCollection 2021 Nov.
A Case of Coombs-Negative Hemolytic Anemia Prompting Diagnosis of SARS-CoV-2


Thanuja Neerukonda[SUP] 1 [/SUP], Walid Moughabel[SUP] 1 [/SUP], Justin Chen[SUP] 1 [/SUP], Devansh Patel[SUP] 1 [/SUP], Faiza Manji[SUP] 2 [/SUP]



Affiliations

Abstract

Case reports have discussed coronavirus disease of 2019 (COVID-19) patients presenting with hemolytic anemia, specifically with a positive direct antiglobulin test. However, Coombs-negative hemolytic anemia in COVID-19 patients has been rarely reported. We present an unusual case of Coombs-negative hemolytic anemia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which responded with evidence-based COVID-19 treatments. We demonstrate the importance of considering SARS-CoV-2 as a cause of Coombs-negative hemolytic anemia, and we illustrate how treatment of the underlying COVID-19 illness, even if it is just supportive care, will help resolve the associated hemolysis.

Keywords: - hematology; coombs' negative; coronavirus disease 2019 (covid-19); hemolytic anaemia; sars-cov-2.
 
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