Covid: Australian vaccine abandoned over false HIV response

[Mary Wilson]

Published: 1 hour ago

A promising Australian candidate for a coronavirus vaccine has been abandoned after trial participants returned false HIV positive results.

Australia had previously agreed to buy 51 million doses of the vaccine being developed by Australian firm CSL and the University of Queensland (UQ).

The government said orders of other vaccines would now fill the shortfall.

CSL and UQ stressed that the positive results were false - meaning trial participants' health was not at risk.

... The vaccine had been in stage one of trials, and proving to be effective in making antibodies.

But it also generated HIV antibodies in some recipients - which meant it showed false positives for HIV. Further testing proved the HIV wasn't there.

CSL and UQ said fixing the flaw would take about a year, prompting a decision to abandon the trial.

https://www.bbc.com/news/world-aust...11EB-8F9B-6BB44744363C&at_custom1=[post+type]

 

[sharon sanders]

bump this

 

[Emily]

Amazing, Mary. Maybe they can use it as an HIV vaccine.

https://www.dailymotion.com/video/x7y0fkr

Scientist claims he warned Govt about abandoned vaccine
ABC NEWS (Australia)
Vaccine scientist Professor Nikolai Petrovesky says he shared his concerns with the federal Health Department. His company, Vaxine, is developing its own coronavirus vaccine

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672035/

The Molecular Clamp is a trimerization motif of 80aa in length (~9.2 kDa) derived from N- and C-terminal heptad repeat (HR) regions of HIV-1 gp41 which self-assemble into a stable six-helical bundle structure that is critical for driving membrane fusion and cell entry of HIV-1