Emily
Editor, Senior Moderator
https://www.medrxiv.org/content/10.1101/2022.12.17.22283625v1.full
Effectiveness of the Coronavirus Disease 2019 (COVID-19) Bivalent Vaccine
Nabin K. Shrestha, Patrick C. Burke, Amy S. Nowacki, James F. Simon, Amanda Hagen, Steven M. Gordon
medRxiv 2022.12.17.22283625; doi: https://doi.org/10.1101/2022.12.17.22283625 This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
Risk of COVID-19 based on prior infection and vaccination history
The risk of COVID-19 varied by the phase of the epidemic in which the subject’s last prior COVID-19 episode occurred. In decreasing order of risk of COVID-19 were those never previously infected, those last infected during the pre-Delta or Delta phase, those last infected during the Omicron BA.1/BA.2 phase, and those last infected during the Omicron BA.4/BA.5 phase (Figure 1).
The risk of COVID-19 also varied by the number of COVID-19 vaccine doses previously received. The higher the number of vaccines previously received, the higher the risk of contracting COVID-19 (Figure 2).
...
The multivariable analyses also found that, the more recent the last prior COVID-19 episode was the lower the risk of COVID-19, and that the greater the number of vaccine doses previously received the higher the risk of COVID-19...
Effectiveness of the Coronavirus Disease 2019 (COVID-19) Bivalent Vaccine
Nabin K. Shrestha, Patrick C. Burke, Amy S. Nowacki, James F. Simon, Amanda Hagen, Steven M. Gordon
medRxiv 2022.12.17.22283625; doi: https://doi.org/10.1101/2022.12.17.22283625 This article is a preprint and has not been peer-reviewed [what does this mean?]. It reports new medical research that has yet to be evaluated and so should not be used to guide clinical practice.
Risk of COVID-19 based on prior infection and vaccination history
The risk of COVID-19 varied by the phase of the epidemic in which the subject’s last prior COVID-19 episode occurred. In decreasing order of risk of COVID-19 were those never previously infected, those last infected during the pre-Delta or Delta phase, those last infected during the Omicron BA.1/BA.2 phase, and those last infected during the Omicron BA.4/BA.5 phase (Figure 1).
The risk of COVID-19 also varied by the number of COVID-19 vaccine doses previously received. The higher the number of vaccines previously received, the higher the risk of contracting COVID-19 (Figure 2).
...
The multivariable analyses also found that, the more recent the last prior COVID-19 episode was the lower the risk of COVID-19, and that the greater the number of vaccine doses previously received the higher the risk of COVID-19...