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COVID-19: 'Real-world' analysis of coronavirus vaccine in Israel raises questions about UK strategy

Gert van der Hoek

In Memoriam - Editor, Senior Moderator
Scientists in Israel have been studying preliminary data from 200,000 vaccinated people.

The first real-world analysis of the Pfizer/BioNTech coronavirus vaccine suggests it is matching its performance in clinical trials, but raises serious questions about the UK's decision to delay the second dose.

Scientists in Israel - which is leading the COVID-19 vaccination race - have told Sky News that they are "very hopeful" having studied preliminary data from 200,000 vaccinated people.

But crucially they say their results do not show efficacy at a level close to that used by the UK to justify delaying the second dose of the Pfizer/BioNtech jab.

Professor Ran Balicer is a physician, epidemiologist and chief innovation officer for Clalit, the largest health care provider in Israel. He is also an adviser to the World Health Organisation.

"We compared 200,000 people above the age of 60 that were vaccinated. We took a comparison group of 200,000 people, same age, not vaccinated, that were matched to this group on various variables..." Prof Balicer said.

"Then we looked to see what is the daily positivity rate... And we saw that there was no difference between vaccinated and unvaccinated until day 14 post-vaccination.
 
"We compared 200,000 people above the age of 60 that were vaccinated. We took a comparison group of 200,000 people, same age, not vaccinated, that were matched to this group on various variables..." Prof Balicer said.

"Then we looked to see what is the daily positivity rate... And we saw that there was no difference between vaccinated and unvaccinated until day 14 post-vaccination.
This does not make much sense. He seems to be saying that you do not get protection for the first 2 weeks after the first injection but that is exactly what you would expect.
 
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