tetano
Editor, Senior Moderator
Diagn Microbiol Infect Dis. 2016 Nov 27. pii: S0732-8893(16)30398-4. doi: 10.1016/j.diagmicrobio.2016.11.015. [Epub ahead of print]
[h=1]Contribution of a rapid influenza diagnostic test to manage hospitalized patients with suspected influenza.[/h] Busson L[SUP]1[/SUP], Mahadeb B[SUP]2[/SUP], De Foor M[SUP]2[/SUP], Vandenberg O[SUP]3[/SUP], Hallin M[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]AIM:[/h] To evaluate the performances of the Alere i influenza A&B test and to appraise its contribution to patient management.
[h=4]METHODS:[/h] In total, 267 samples were tested. Influenza A and B PCR was performed as the reference. For each positive result, the supervising physician was contacted to collect data regarding patient management.
[h=4]FINDINGS:[/h] The overall sensitivity and specificity of the Alere i were 91.4% and 97.6% for influenza A and 54.5% and 98.8% for influenza B, respectively. More specifically, when used in the emergency room (ER), the test helped avoid 10.7% of hospitalizations, 46.4% of antibiotic prescriptions and 42.9% of additional investigations for positive patients. The test was also helpful in instituting the prescription of oseltamivir and patient isolation.
[h=4]CONCLUSION:[/h] Alere i influenza A&B is a rapid, sensitive and specific diagnostic test for influenza A. Sensitivity for influenza B was poor. Its usefulness was more important when patients were still in the ER.
Copyright ? 2016. Published by Elsevier Inc.
[h=4]KEYWORDS:[/h] Alere i; Clinical contribution; Diagnosis; Influenza; Sofia
PMID: 27939284 DOI: 10.1016/j.diagmicrobio.2016.11.015
[PubMed - as supplied by publisher]
[h=1]Contribution of a rapid influenza diagnostic test to manage hospitalized patients with suspected influenza.[/h] Busson L[SUP]1[/SUP], Mahadeb B[SUP]2[/SUP], De Foor M[SUP]2[/SUP], Vandenberg O[SUP]3[/SUP], Hallin M[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]AIM:[/h] To evaluate the performances of the Alere i influenza A&B test and to appraise its contribution to patient management.
[h=4]METHODS:[/h] In total, 267 samples were tested. Influenza A and B PCR was performed as the reference. For each positive result, the supervising physician was contacted to collect data regarding patient management.
[h=4]FINDINGS:[/h] The overall sensitivity and specificity of the Alere i were 91.4% and 97.6% for influenza A and 54.5% and 98.8% for influenza B, respectively. More specifically, when used in the emergency room (ER), the test helped avoid 10.7% of hospitalizations, 46.4% of antibiotic prescriptions and 42.9% of additional investigations for positive patients. The test was also helpful in instituting the prescription of oseltamivir and patient isolation.
[h=4]CONCLUSION:[/h] Alere i influenza A&B is a rapid, sensitive and specific diagnostic test for influenza A. Sensitivity for influenza B was poor. Its usefulness was more important when patients were still in the ER.
Copyright ? 2016. Published by Elsevier Inc.
[h=4]KEYWORDS:[/h] Alere i; Clinical contribution; Diagnosis; Influenza; Sofia
PMID: 27939284 DOI: 10.1016/j.diagmicrobio.2016.11.015
[PubMed - as supplied by publisher]