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Comparison of the epidemiology of laboratory-confirmed influenza A and influenza B cases in Manitoba, Canada

tetano

Editor, Senior Moderator
BMC Public Health. 2015 Jan 30;15(1):35. [Epub ahead of print]
[h=1]Comparison of the epidemiology of laboratory-confirmed influenza A and influenza B cases in Manitoba, Canada.[/h] Hinds AM, Bozat-Emre S, Van Caeseele P, Mahmud SM.
[h=3]Abstract[/h] BackgroundDespite the public health significance of annual influenza outbreaks, the literature comparing the epidemiology of influenza A and B infections is limited and dated and may not reflect recent trends. In Canada, the relative contribution of influenza A and B to the burden of morbidity is not well understood. We examined rates of laboratory-confirmed cases of influenza A and B (LCI-A and LCI-B) in the Canadian province of Manitoba between 1993 and 2008 and compared cases of the two types in terms of socio-demographic and clinical characteristics.MethodsLaboratory-confirmed cases of influenza A and B in Manitoba between 1993 and 2008 were identified from the Cadham Provincial Laboratory (CPL) Database and linked to de-identified provincial administrative health records. Crude and age-adjusted incidence rates of LCI-A and LCI-B were calculated. Demographic characteristics, health status, health service use, and vaccination history were compared by influenza type.ResultsOver the study period, 1,404 of LCI-A and 445 cases of LCI-B were diagnosed, corresponding to an annual age-standardized rate of 7.2 (95% CI: 6.5-7.9) for LCI-A and 2.2 (CI: 1.5 ? 3.0) per 100,000 person-years for LCI-B. Annual rates fluctuated widely but there was less variation in the LCI-B rates. For LCI-A, but not LCI-B, incidence was inversely related to household income. Older age, urban residence and past hospitalization were associated with increased detection of LCI-A whereas receipt of the influenza vaccine was associated with decreased LCI-A detection. Once socio-demographic variables were controlled, having a pre-existing chronic disease or immune suppression was not related to influenza type.ConclusionInfluenza A and B affected different segments of the population. Older age was associated with increased LCI-A detection, but not pre-existing chronic diseases. This information may be useful to public health professionals in planning and evaluating new and existing seasonal influenza vaccines.


PMID: 25633280 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25633280
 
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