Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Mi

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Genome Announc. 2015 Jul 30;3(4). pii: e00676-15. doi: 10.1128/genomeA.00676-15.
[h=1]Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014.[/h] Mishel P[SUP]1[/SUP], Ojala T[SUP]2[/SUP], Benner C[SUP]1[/SUP], Lakspere T[SUP]1[/SUP], Bychkov D[SUP]1[/SUP], Jalovaara P[SUP]1[/SUP], Kakkola L[SUP]3[/SUP], Kallio-Kokko H[SUP]4[/SUP], Kantele A[SUP]5[/SUP], Kankainen M[SUP]1[/SUP], Ikonen N[SUP]6[/SUP], Ripatti S[SUP]7[/SUP], Julkunen I[SUP]3[/SUP], Kainov DE[SUP]8[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Here, we report 40 new whole-genome sequences of influenza A(H1N1)pdm09 viruses isolated from Finnish patients during 2009 to 2014. A preliminary analysis of these and 186 other whole genomes of influenza A(H1N1)pdm09 viruses isolated from hospitalized and nonhospitalized patients during 2009 to 2014 in Finland revealed several viral mutations that might be associated with patient hospitalizations.
Copyright ? 2015 Mishel et al.


PMID: 26227588 [PubMed] PMCID: PMC4520887 Free PMC Article