tetano
Editor, Senior Moderator
Comp Immunol Microbiol Infect Dis
. 2020 Oct 14;73:101562.
doi: 10.1016/j.cimid.2020.101562. Online ahead of print.
Serological evidence of avian influenza virus subtype H5 and H9 in live bird market, Myanmar
Thant Nyi Lin[SUP] 1 [/SUP], Napawan Bunpapong[SUP] 2 [/SUP], Supanat Boonyapisitsopa[SUP] 3 [/SUP], Supassama Chaiyawong[SUP] 4 [/SUP], Taveesak Janetanakit[SUP] 5 [/SUP], Khin Thu Rain[SUP] 6 [/SUP], Pont Pont Mon[SUP] 7 [/SUP], Sandi Myint Oo[SUP] 8 [/SUP], Aunyaratana Thontiravong[SUP] 9 [/SUP], Alongkorn Amonsin[SUP] 10 [/SUP]
Affiliations
Abstract
Avian Influenza (AI), caused by Alphainfluenzaviruses (AIVs), is a contagious respiratory disease in birds and mammals. AIVs have been reported in poultry worldwide and the impact of AIVs on human health is immense. In this study, a serological survey of AIV subtype H5 and H9 was conducted in a live bird market (LBM) in Yangon, Myanmar during February 2016 to September 2016. A total of 621 serum samples were collected from chickens (n = 489) and ducks (n = 132) from 48 vendors in the LBM. The samples were examined for antibodies against influenza viruses by using NP-ELISA and specific antibodies against AIV-H5N1 (Clade 2.3.4) and AIV-H9N2 (Clade 9.4.2) by using Hemagglutination Inhibition (HI) assay. The result of NP-ELISA assay showed that 12.88 % (80/621) of poultry in LBM was positive for AIV antibodies. In detail, 38.06 % (51/134) of layers, 7.08 % (8/113) of backyard chicken, 2.07 % (5/242) of broilers and 12.12 % (16/132) of ducks were AIV positive. The HI test for specific antibodies against AIV-H5N1 and AIV-H9N2 were 1.77 % (11/621) and 4.51 % (28/621), respectively. Our findings revealed the evidence of AIV-H5N1 and AIV-H9N2 exposure in both chicken and ducks in the LBM in Yangon, Myanmar. Risks of influenza infections and transmission among poultry and humans in the LBMs could not be ignored.
Keywords: Avian influenza; Live bird market; Myanmar; Serology; Survey.
. 2020 Oct 14;73:101562.
doi: 10.1016/j.cimid.2020.101562. Online ahead of print.
Serological evidence of avian influenza virus subtype H5 and H9 in live bird market, Myanmar
Thant Nyi Lin[SUP] 1 [/SUP], Napawan Bunpapong[SUP] 2 [/SUP], Supanat Boonyapisitsopa[SUP] 3 [/SUP], Supassama Chaiyawong[SUP] 4 [/SUP], Taveesak Janetanakit[SUP] 5 [/SUP], Khin Thu Rain[SUP] 6 [/SUP], Pont Pont Mon[SUP] 7 [/SUP], Sandi Myint Oo[SUP] 8 [/SUP], Aunyaratana Thontiravong[SUP] 9 [/SUP], Alongkorn Amonsin[SUP] 10 [/SUP]
Affiliations
- PMID: 33091862
- DOI: 10.1016/j.cimid.2020.101562
Abstract
Avian Influenza (AI), caused by Alphainfluenzaviruses (AIVs), is a contagious respiratory disease in birds and mammals. AIVs have been reported in poultry worldwide and the impact of AIVs on human health is immense. In this study, a serological survey of AIV subtype H5 and H9 was conducted in a live bird market (LBM) in Yangon, Myanmar during February 2016 to September 2016. A total of 621 serum samples were collected from chickens (n = 489) and ducks (n = 132) from 48 vendors in the LBM. The samples were examined for antibodies against influenza viruses by using NP-ELISA and specific antibodies against AIV-H5N1 (Clade 2.3.4) and AIV-H9N2 (Clade 9.4.2) by using Hemagglutination Inhibition (HI) assay. The result of NP-ELISA assay showed that 12.88 % (80/621) of poultry in LBM was positive for AIV antibodies. In detail, 38.06 % (51/134) of layers, 7.08 % (8/113) of backyard chicken, 2.07 % (5/242) of broilers and 12.12 % (16/132) of ducks were AIV positive. The HI test for specific antibodies against AIV-H5N1 and AIV-H9N2 were 1.77 % (11/621) and 4.51 % (28/621), respectively. Our findings revealed the evidence of AIV-H5N1 and AIV-H9N2 exposure in both chicken and ducks in the LBM in Yangon, Myanmar. Risks of influenza infections and transmission among poultry and humans in the LBMs could not be ignored.
Keywords: Avian influenza; Live bird market; Myanmar; Serology; Survey.