tetano
Editor, Senior Moderator
J Infect. 2013 Jun 6. pii: S0163-4453(13)00131-X. doi: 10.1016/j.jinf.2013.05.006. [Epub ahead of print]
Community-acquired pneumonia during the first post-pandemic influenza season: A prospective, multicentre cohort (postp10-11) study from Spain.
Viasus D, Marinescu C, Villoslada A, Cordero E, G?lvez-Acebal J, Fari?as MC, Gracia-Ahufinger I, Fern?ndez-Navarro A, Niub? J, Ortega L, Mu?ez-Rubio E, Romero-G?mez MP, Carratal? J.
Source
Hospital Universitari de Bellvitge - IDIBELL, University of Barcelona, Feixa Llarga s/n, Postal code 08907, Barcelona, Spain. Electronic address: dfviasusp@unal.edu.co.
Abstract
OBJECTIVES:
To determine the aetiology, clinical features and prognosis of CAP during the first post-pandemic influenza season. We also assessed the factors associated with severe disease and tested the ability of a scoring system for identifying influenza A (H1N1)pdm09-related pneumonia.
METHODS:
Prospective cohort study carried out at 10 tertiary hospitals of Spain. All adults hospitalised with CAP from December 01, 2010 to March 31, 2011 were analysed.
RESULTS:
A total of 747 adults with CAP required hospitalisation. The aetiology was determined in 315 (42.2%) patients, in whom 154 (21.9%) were due to bacteria, 125 (16.7%) were due to viruses and 36 (4.8%) were mixed (due to viruses and bacteria). The most frequently isolated bacteria were Streptococccus pneumoniae. Among patients with viral pneumonia, the most common organism identified were influenza A (H1N1)pdm09. Independent factors associated with severe disease were impaired consciousness, septic shock, tachypnea, hyponatremia, hypoxemia, influenza B, and influenza A (H1N1)pdm09. The scoring system evaluated did not differentiate reliably between patients with influenza A (H1N1)pdm09-related pneumonia and those with other aetiologies.
CONCLUSIONS:
The frequency of bacterial and viral pneumonia during the first post-pandemic influenza season was similar. The main identified virus was influenza A (H1N1)pdm09, which was associated with severe disease. Although certain presenting clinical features may allow recognition of influenza A (H1N1)pdm09-related pneumonia, it is difficult to express them in a reliable scoring system.
Copyright ? 2013. Published by Elsevier Ltd.
PMID:
23747416
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23747416
Community-acquired pneumonia during the first post-pandemic influenza season: A prospective, multicentre cohort (postp10-11) study from Spain.
Viasus D, Marinescu C, Villoslada A, Cordero E, G?lvez-Acebal J, Fari?as MC, Gracia-Ahufinger I, Fern?ndez-Navarro A, Niub? J, Ortega L, Mu?ez-Rubio E, Romero-G?mez MP, Carratal? J.
Source
Hospital Universitari de Bellvitge - IDIBELL, University of Barcelona, Feixa Llarga s/n, Postal code 08907, Barcelona, Spain. Electronic address: dfviasusp@unal.edu.co.
Abstract
OBJECTIVES:
To determine the aetiology, clinical features and prognosis of CAP during the first post-pandemic influenza season. We also assessed the factors associated with severe disease and tested the ability of a scoring system for identifying influenza A (H1N1)pdm09-related pneumonia.
METHODS:
Prospective cohort study carried out at 10 tertiary hospitals of Spain. All adults hospitalised with CAP from December 01, 2010 to March 31, 2011 were analysed.
RESULTS:
A total of 747 adults with CAP required hospitalisation. The aetiology was determined in 315 (42.2%) patients, in whom 154 (21.9%) were due to bacteria, 125 (16.7%) were due to viruses and 36 (4.8%) were mixed (due to viruses and bacteria). The most frequently isolated bacteria were Streptococccus pneumoniae. Among patients with viral pneumonia, the most common organism identified were influenza A (H1N1)pdm09. Independent factors associated with severe disease were impaired consciousness, septic shock, tachypnea, hyponatremia, hypoxemia, influenza B, and influenza A (H1N1)pdm09. The scoring system evaluated did not differentiate reliably between patients with influenza A (H1N1)pdm09-related pneumonia and those with other aetiologies.
CONCLUSIONS:
The frequency of bacterial and viral pneumonia during the first post-pandemic influenza season was similar. The main identified virus was influenza A (H1N1)pdm09, which was associated with severe disease. Although certain presenting clinical features may allow recognition of influenza A (H1N1)pdm09-related pneumonia, it is difficult to express them in a reliable scoring system.
Copyright ? 2013. Published by Elsevier Ltd.
PMID:
23747416
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23747416