Gert van der Hoek
In Memoriam - Editor, Senior Moderator
Community-acquired multidrug-resistant Gram-negative bacterial infective endocarditis
Sowjanya Naha1, Kushal Naha1, Vasudev Acharya1, H Manjunath Hande1, G Vivek2
+ Author Affiliations
1Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India
2Department of Cardiology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
Correspondence to
Dr Ganapathiraman Vivek, vivekgraman@gmail.com
Accepted 21 July 2014
Published 5 August 2014
Summary
We describe two cases of bacterial endocarditis secondary to multidrug-resistant Gram-negative organisms. In both cases, the diagnosis was made in accordance with the modified Duke's criteria and confirmed by histopathological analysis.
Furthermore, in both instances there were no identifiable sources of bacteraemia and no history of contact with hospital or other medical services prior to the onset of symptoms.
The patients were managed in similar fashion with prolonged broad-spectrum antibiotic therapy and surgical intervention and made complete recoveries.
These cases highlight Gram-negative organisms as potential agents for endocarditis, as well as expose the dissemination of such multidrug-resistant bacteria into the community.
The application of an integrated medical and surgical approach and therapeutic dilemmas encountered in managing these cases are described.
BMJ
Endocarditis
thanks to David Evans
.
Sowjanya Naha1, Kushal Naha1, Vasudev Acharya1, H Manjunath Hande1, G Vivek2
+ Author Affiliations
1Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India
2Department of Cardiology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India
Correspondence to
Dr Ganapathiraman Vivek, vivekgraman@gmail.com
Accepted 21 July 2014
Published 5 August 2014
Summary
We describe two cases of bacterial endocarditis secondary to multidrug-resistant Gram-negative organisms. In both cases, the diagnosis was made in accordance with the modified Duke's criteria and confirmed by histopathological analysis.
Furthermore, in both instances there were no identifiable sources of bacteraemia and no history of contact with hospital or other medical services prior to the onset of symptoms.
The patients were managed in similar fashion with prolonged broad-spectrum antibiotic therapy and surgical intervention and made complete recoveries.
These cases highlight Gram-negative organisms as potential agents for endocarditis, as well as expose the dissemination of such multidrug-resistant bacteria into the community.
The application of an integrated medical and surgical approach and therapeutic dilemmas encountered in managing these cases are described.
BMJ
Endocarditis
thanks to David Evans
.