Cochrane: Does oseltamivir really reduce complications of influenza?

[tetano]

Clin Infect Dis. 2011 Dec;53(12):1302-3.
Does oseltamivir really reduce complications of influenza?
Cochrane Neuraminidase Inhibitors Review Team.

PMID:
22080124
[PubMed - in process]


http://www.ncbi.nlm.nih.gov/pubmed/22080124

 

[Giuseppe]

Re: Cochrane: Does oseltamivir really reduce complications of influenza?

It seems well acknowledged that early initiation of oseltamivir treatment of patients with severe influenza A infection reduces the mortality rate, for example in Vietnam and Indonesia, where A(H5N1) clinical course was thoroughly studied.

See for example: http://www.ncbi.nlm.nih.gov/pubmed/19435433

And the other works of Jeremy Farrar: http://www.ncbi.nlm.nih.gov/pubmed?term="Farrar J"[Author]

 

[gsgs]

Re: Cochrane: Does oseltamivir really reduce complications of influenza?

http://www.ncbi.nlm.nih.gov/pubmed/21677258


http://www.cidrap.umn.edu/cidrap/content/influenza/general/news/jan1912cochrane.html

drug shortens the time to alleviation of symptoms by an average of about 21 hours,
from the average of 160 hours of symptoms in placebo-group patients.
But from seven studies that examined the question, they found no effect
on the rate of hospitalizations.


http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008965.pub3/abstract