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Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Kore

tetano

Editor, Senior Moderator
J Korean Med Sci. 2017 Mar;32(3):407-414. doi: 10.3346/jkms.2017.32.3.407.
[h=1]Clinical Features of Influenza and Acute Respiratory Illness in Older Adults at Least 50 Years of Age in an Outpatient Setting in the Republic of Korea: a Prospective, Observational, Cohort Study.[/h] Kim WJ[SUP]1[/SUP], Lee JS[SUP]2[/SUP], Lee CK[SUP]3[/SUP], Cheong HJ[SUP]4[/SUP], Kim M[SUP]4[/SUP], Monegal JS[SUP]5[/SUP], Carneiro R[SUP]5[/SUP], Kyaw MH[SUP]5[/SUP], Haguinet F[SUP]5[/SUP], Ray R[SUP]5[/SUP], Matias G[SUP]5[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Two prospective, multi-centre, observational studies (GlaxoSmithKline [GSK] identifier No. 110938 and 112519) were performed over 2 influenza seasons (2007-2008 and 2008-2009) in the Republic of Korea (ROK) with the aim to evaluate the burden of laboratory-confirmed influenza (LCI) in patients ≥ 50 years of age seeking medical attention for acute respiratory illness (ARI). The median participant age was 58 years in the 2007-2008 season and 60 years in the 2008-2009 season. LCI was observed in 101/346 (29.2%) of ARI patients in the 2007-2008 season and in 166/443 (37.5%) of ARI patients in the 2008-2009 season. Compared to patients with non-influenza ARI, those with LCI had higher rates of decreased daily activities (60.4% vs. 32.9% in 2007-2008 and 46.4% vs. 25.8% in 2008-2009), work absenteeism (51.1% vs. 25.6% and 14.4% vs. 7.7%), and longer duration of illness. These results indicated that influenza is an important cause of ARI in adults aged 50 and older causing more severe illness than non-influenza related ARI.


[h=4]KEYWORDS:[/h] Acute Respiratory Illness; Adult; Epidemiology; Influenza; Republic of Korea

PMID: 28145642 DOI: 10.3346/jkms.2017.32.3.407
[PubMed - in process] Free full text
 
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