tetano
Editor, Senior Moderator
Pediatr Infect Dis J. 2011 Dec 14. [Epub ahead of print]
Clinical Features of Infants Hospitalized for 2009 Pandemic Influenza A (H1N1) in Japan: Analysis Using a National Hospital Discharge Database.
Takeuchi M, Yasunaga H, Horiguchi H, Matsuda S.
Source
*Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan ?Department of Health Management and Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan ?Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Fukuoka, Japan.
Abstract
BACKGROUND:
Earlier studies reported that infants <12 months of age were at high risk of hospitalization for 2009 pandemic influenza A H1N1 virus (2009 H1N1) infection, but there was little information about the clinical courses in these patients.
METHODS:
A retrospective study was performed using the nationwide inpatient Diagnosis Procedure Combination Database in Japan. We searched hospitalizations between July and December 2009, of infants (<12 months) and children 12 to <24 months of age with influenza. We examined their demographic data and hospitalization details including treatment, complications and outcomes.
RESULTS:
During the study period, 1,023 infants were hospitalized for influenza; 98.1% of them were previously healthy. Complications attributed to influenza were found in 181 (17.7%) infants, including 3 critical illnesses and 1 death. Oseltamivir was prescribed to 535 (53.3%) infants. We found no evidence that oseltamivir was associated with either complications or length of hospital stay. During the same period, 579 children 1 year of age were admitted for 2009 H1N1, and 56.5% of them had influenza-related complications.
CONCLUSIONS:
In Japan, infants with 2009 H1N1 were twice as likely to be hospitalized as children 1 year of age and older. However, the clinical course of the hospitalized infants was generally uncomplicated.
PMID:
22173135
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22173135
Clinical Features of Infants Hospitalized for 2009 Pandemic Influenza A (H1N1) in Japan: Analysis Using a National Hospital Discharge Database.
Takeuchi M, Yasunaga H, Horiguchi H, Matsuda S.
Source
*Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan ?Department of Health Management and Policy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan ?Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Fukuoka, Japan.
Abstract
BACKGROUND:
Earlier studies reported that infants <12 months of age were at high risk of hospitalization for 2009 pandemic influenza A H1N1 virus (2009 H1N1) infection, but there was little information about the clinical courses in these patients.
METHODS:
A retrospective study was performed using the nationwide inpatient Diagnosis Procedure Combination Database in Japan. We searched hospitalizations between July and December 2009, of infants (<12 months) and children 12 to <24 months of age with influenza. We examined their demographic data and hospitalization details including treatment, complications and outcomes.
RESULTS:
During the study period, 1,023 infants were hospitalized for influenza; 98.1% of them were previously healthy. Complications attributed to influenza were found in 181 (17.7%) infants, including 3 critical illnesses and 1 death. Oseltamivir was prescribed to 535 (53.3%) infants. We found no evidence that oseltamivir was associated with either complications or length of hospital stay. During the same period, 579 children 1 year of age were admitted for 2009 H1N1, and 56.5% of them had influenza-related complications.
CONCLUSIONS:
In Japan, infants with 2009 H1N1 were twice as likely to be hospitalized as children 1 year of age and older. However, the clinical course of the hospitalized infants was generally uncomplicated.
PMID:
22173135
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22173135