tetano
Editor, Senior Moderator
Adv Exp Med Biol. 2013;788:89-96. doi: 10.1007/978-94-007-6627-3_14.
Clinical features and outcomes of influenza a and B infections in children.
Nitsch-Osuch A, Wozniak-Kosek A, Korzeniewski K, Zycinska K, Wardyn K, Brydak LB.
Source
Department of Family Medicine, Warsaw Medical University, 1A Banacha St., Bldg. F, 02-097, Warsaw, Poland, anitsch@amwaw.edu.pl.
Abstract
The aim of the study was to describe the course of influenza among children aged 0-59 months. A total of 150 children with influenza-like symptoms (ILI): cough, fever >37.8 ?C, and sore throat was included into the observation. All children were tested with both rapid influenza detection test (RIDT) BD Directigen? EZ Flu A+B? and RT-PCR. Sixty four cases of influenza were diagnosed (incidence rate 40 %): 19 (30 %) cases of influenza caused by type B virus and 45 (70 %) cases caused by type A virus. Children with influenza required more often follow up visits (p < 0.05, OR 1.99, 95 % CI 1.03-3.85) and less often were administrated antibiotic therapy (p < 0.05, OR 0.25, 95 % CI 0.04-0.97). The logistic regression analysis revealed that only positive result of rapid influenza detection test, not any of clinical symptoms, could be found as an independent predictor of influenza (OR 4.37, 95 % CI 2.03-9.43). Patients with influenza type A more often reported muscle ache (p < 0.05) and complications (p < 0.05; OR 6.06, 95 % CI 1.20-60.38). Otitis media occurred more often among patients with than without influenza (p < 0.01; OR 15.50, 95 % CI 2.10-688.5). We conclude that although influenza infections among children younger than 59 months were generally mild and self-limited, pediatric burden of the disease was significant.
PMID:
23835964
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23835964
Clinical features and outcomes of influenza a and B infections in children.
Nitsch-Osuch A, Wozniak-Kosek A, Korzeniewski K, Zycinska K, Wardyn K, Brydak LB.
Source
Department of Family Medicine, Warsaw Medical University, 1A Banacha St., Bldg. F, 02-097, Warsaw, Poland, anitsch@amwaw.edu.pl.
Abstract
The aim of the study was to describe the course of influenza among children aged 0-59 months. A total of 150 children with influenza-like symptoms (ILI): cough, fever >37.8 ?C, and sore throat was included into the observation. All children were tested with both rapid influenza detection test (RIDT) BD Directigen? EZ Flu A+B? and RT-PCR. Sixty four cases of influenza were diagnosed (incidence rate 40 %): 19 (30 %) cases of influenza caused by type B virus and 45 (70 %) cases caused by type A virus. Children with influenza required more often follow up visits (p < 0.05, OR 1.99, 95 % CI 1.03-3.85) and less often were administrated antibiotic therapy (p < 0.05, OR 0.25, 95 % CI 0.04-0.97). The logistic regression analysis revealed that only positive result of rapid influenza detection test, not any of clinical symptoms, could be found as an independent predictor of influenza (OR 4.37, 95 % CI 2.03-9.43). Patients with influenza type A more often reported muscle ache (p < 0.05) and complications (p < 0.05; OR 6.06, 95 % CI 1.20-60.38). Otitis media occurred more often among patients with than without influenza (p < 0.01; OR 15.50, 95 % CI 2.10-688.5). We conclude that although influenza infections among children younger than 59 months were generally mild and self-limited, pediatric burden of the disease was significant.
PMID:
23835964
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23835964