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Clinical Characteristics and Viral RNA Detection in Children With Coronavirus Disease 2019 in the Republic of Korea

Mary Wilson

Well-known member
August 28, 2020

Mi Seon Han, MD, PhD[SUP]1[/SUP]; Eun Hwa Choi, MD, PhD[SUP]2[/SUP]; Sung Hee Chang, MD[SUP]3[/SUP]; et al

JAMA Pediatr. Published online August 28, 2020. doi:10.1001/jamapediatrics.2020.3988

Question How long is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA detected in children, and are children with coronavirus disease 2019 (COVID-19) identifiable by symptoms?

Findings In this case series of 91 children with COVID-19 in Korea, 22.0% were asymptomatic. Only 8.5% of symptomatic cases were diagnosed at the time of symptom onset, while 66.2% had unrecognized symptoms before diagnosis and 25.4% developed symptoms after diagnosis; SARS-CoV-2 RNA was detected for a mean of 17.6 days overall and 14.1 days in asymptomatic cases.

Meaning Symptom screening fails to identify most COVID-19 cases in children, and SARS-CoV-2 RNA in children is detected for an unexpectedly long time.

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2770150
 
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