tetano
Editor, Senior Moderator
Clin Transplant
. 2020 Nov 28;e14169.
doi: 10.1111/ctr.14169. Online ahead of print.
Favorable Outcome of COVID-19 among African American (AA) Renal Transplant Recipients in Detroit
Claudia D Jarrin Tejada[SUP] 1 [/SUP], Mareena Zachariah[SUP] 2 [/SUP], Angela Beatriz V Cruz[SUP] 1 [/SUP], Shakir Hussein[SUP] 3 [/SUP], Elizabeth Wipula[SUP] 4 [/SUP], Nicole Meeks[SUP] 5 [/SUP], Jeff Wolff[SUP] 4 [/SUP], Pranatharthi H Chandrasekar[SUP] 1 [/SUP]
Affiliations
Abstract
Transplant recipients are vulnerable to infections, including COVID-19, given their comorbidities and chronic immunosuppression. In this study, all hospitalized renal transplant recipients (RTR) with a positive nasal swab for Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV2) seen consecutively between 03/01/2020 and 05/01/2020 at the Detroit Medical Center were included. Data on demographics, clinical presentation, laboratory findings, management and outcomes were collected. Twenty-five patients, were included, all African American (AA) and deceased donor transplant recipients. The most common presenting symptom was dyspnea, followed by fever, cough and diarrhea. Multifocal opacities on initial chest x-ray were seen in 52% patients and 44% of patients had a presenting oxygen saturation of less than or equal to 94%. Four patients (16%) required transfer to the intensive care unit, one required intubation and one expired. COVID-19 infected RTR in this cohort had low mortality of 4% (n=1). Despite multiple co-morbidities and chronic immunosuppression, our cohort of African American RTR had favorable outcomes compared to other reports on COVID-19 in RTR.
. 2020 Nov 28;e14169.
doi: 10.1111/ctr.14169. Online ahead of print.
Favorable Outcome of COVID-19 among African American (AA) Renal Transplant Recipients in Detroit
Claudia D Jarrin Tejada[SUP] 1 [/SUP], Mareena Zachariah[SUP] 2 [/SUP], Angela Beatriz V Cruz[SUP] 1 [/SUP], Shakir Hussein[SUP] 3 [/SUP], Elizabeth Wipula[SUP] 4 [/SUP], Nicole Meeks[SUP] 5 [/SUP], Jeff Wolff[SUP] 4 [/SUP], Pranatharthi H Chandrasekar[SUP] 1 [/SUP]
Affiliations
- PMID: 33247978
- DOI: 10.1111/ctr.14169
Abstract
Transplant recipients are vulnerable to infections, including COVID-19, given their comorbidities and chronic immunosuppression. In this study, all hospitalized renal transplant recipients (RTR) with a positive nasal swab for Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV2) seen consecutively between 03/01/2020 and 05/01/2020 at the Detroit Medical Center were included. Data on demographics, clinical presentation, laboratory findings, management and outcomes were collected. Twenty-five patients, were included, all African American (AA) and deceased donor transplant recipients. The most common presenting symptom was dyspnea, followed by fever, cough and diarrhea. Multifocal opacities on initial chest x-ray were seen in 52% patients and 44% of patients had a presenting oxygen saturation of less than or equal to 94%. Four patients (16%) required transfer to the intensive care unit, one required intubation and one expired. COVID-19 infected RTR in this cohort had low mortality of 4% (n=1). Despite multiple co-morbidities and chronic immunosuppression, our cohort of African American RTR had favorable outcomes compared to other reports on COVID-19 in RTR.