tetano
Editor, Senior Moderator
Clin Obstet Gynecol
. 2022 Mar 1;65(1):195-202.
doi: 10.1097/GRF.0000000000000667.
Vertical Transmission and Neonatal Outcomes Following Maternal SARS-CoV-2 Infection During Pregnancy
Margaret H Kyle[SUP] 1 [/SUP], Maha Hussain[SUP] 1 [/SUP], Victoria Saltz[SUP] 2 [/SUP], Isabelle Mollicone[SUP] 1 [/SUP], Mary Bence[SUP] 1 [/SUP], Dani Dumitriu[SUP] 1 3 4 [/SUP]
Affiliations
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 200 million people worldwide and has likely exposed millions of neonates to SARS-CoV-2 in utero. A large body of literature has examined the possibility of vertical transmission from pregnant women infected with SARS-CoV-2 to their neonates. In this chapter, we review mechanisms of-and evidence for-vertical transmission of SARS-CoV-2, including transplacental, through other biospecimens and breastfeeding, and discuss neonatal outcomes following in utero exposure. Based on the available literature, we conclude vertical transmission of SARS-CoV-2 is rare, and exposed neonates generally show favorable health outcomes.
. 2022 Mar 1;65(1):195-202.
doi: 10.1097/GRF.0000000000000667.
Vertical Transmission and Neonatal Outcomes Following Maternal SARS-CoV-2 Infection During Pregnancy
Margaret H Kyle[SUP] 1 [/SUP], Maha Hussain[SUP] 1 [/SUP], Victoria Saltz[SUP] 2 [/SUP], Isabelle Mollicone[SUP] 1 [/SUP], Mary Bence[SUP] 1 [/SUP], Dani Dumitriu[SUP] 1 3 4 [/SUP]
Affiliations
- PMID: 35045041
- DOI: 10.1097/GRF.0000000000000667
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 200 million people worldwide and has likely exposed millions of neonates to SARS-CoV-2 in utero. A large body of literature has examined the possibility of vertical transmission from pregnant women infected with SARS-CoV-2 to their neonates. In this chapter, we review mechanisms of-and evidence for-vertical transmission of SARS-CoV-2, including transplacental, through other biospecimens and breastfeeding, and discuss neonatal outcomes following in utero exposure. Based on the available literature, we conclude vertical transmission of SARS-CoV-2 is rare, and exposed neonates generally show favorable health outcomes.