tetano
Editor, Senior Moderator
Clin Med Insights Case Rep
. 2023 Jun 19;16:11795476231181560.
doi: 10.1177/11795476231181560. eCollection 2023. Subacute Thyroiditis Complicating COVID-19 Infection
Katrin Henke[SUP] 1 [/SUP], Jonas Odermatt[SUP] 1 [/SUP], Mairi Ziaka[SUP] 1 [/SUP], Natalia Rudovich[SUP] 1 2 [/SUP]
Affiliations
Subacute thyroiditis (SAT) is a self-limited inflammatory disease and a rare cause of thyrotoxicosis. Although the exact etiology of SAT is not sufficiently understood, it is generally associated to viral infections. Current evidence highlights that SAT may be a potentially uncommon manifestation of ongoing Coronavirus disease 2019 (COVID-19) infection or a post-viral complication of the disease. Despite that SAT is a rare manifestation associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease both in ongoing and resolved COVID-19 infection, the ever-increasing numbers of COVID-19 patients strengthens the possibility that this particular disease entity will be of more immediate concern in the future. The current work aims to summarize the approach of SARS-CoV-2-associated SAT, present its pathophysiology, outline current research evidence found in the literature, and discuss potential differential diagnoses and diagnostic dilemmas through an illustrative case.
Keywords: COVID-19; endocrinology; hyperthyroidism; subacute thyroiditis; thyroid disease.
. 2023 Jun 19;16:11795476231181560.
doi: 10.1177/11795476231181560. eCollection 2023. Subacute Thyroiditis Complicating COVID-19 Infection
Katrin Henke[SUP] 1 [/SUP], Jonas Odermatt[SUP] 1 [/SUP], Mairi Ziaka[SUP] 1 [/SUP], Natalia Rudovich[SUP] 1 2 [/SUP]
Affiliations
- PMID: 37351465
- PMCID: PMC10280117
- DOI: 10.1177/11795476231181560
Subacute thyroiditis (SAT) is a self-limited inflammatory disease and a rare cause of thyrotoxicosis. Although the exact etiology of SAT is not sufficiently understood, it is generally associated to viral infections. Current evidence highlights that SAT may be a potentially uncommon manifestation of ongoing Coronavirus disease 2019 (COVID-19) infection or a post-viral complication of the disease. Despite that SAT is a rare manifestation associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease both in ongoing and resolved COVID-19 infection, the ever-increasing numbers of COVID-19 patients strengthens the possibility that this particular disease entity will be of more immediate concern in the future. The current work aims to summarize the approach of SARS-CoV-2-associated SAT, present its pathophysiology, outline current research evidence found in the literature, and discuss potential differential diagnoses and diagnostic dilemmas through an illustrative case.
Keywords: COVID-19; endocrinology; hyperthyroidism; subacute thyroiditis; thyroid disease.