tetano
Editor, Senior Moderator
Clin Liver Dis
. 2023 Feb;27(1):27-45.
doi: 10.1016/j.cld.2022.08.003. Epub 2022 Aug 18.
Coronavirus Disease-2019 and Implications on the Liver
Patrick T Campbell[SUP] 1 [/SUP], Oren K Fix[SUP] 2 [/SUP]
Affiliations
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has had a large impact on patients with chronic liver disease (CLD) and liver transplantation (LT) recipients. Patients with advanced CLD are at a significantly increased risk of poor outcomes in the setting of severe acute respiratory syndrome coronavirus 2 infection. The pandemic has also considerably altered the management and care that is provided to patients with CLD, pre-LT patients, and LT recipients. Vaccination against COVID-19 protects patients with CLD and LT recipients from adverse outcomes and is safe in these patients; however, vaccine efficacy may be reduced in LT recipients and other immunosuppressed patients.
Keywords: Cirrhosis; Immunosuppression; SARS-CoV-2; Transplant; Vaccination.
. 2023 Feb;27(1):27-45.
doi: 10.1016/j.cld.2022.08.003. Epub 2022 Aug 18.
Coronavirus Disease-2019 and Implications on the Liver
Patrick T Campbell[SUP] 1 [/SUP], Oren K Fix[SUP] 2 [/SUP]
Affiliations
- PMID: 36400465
- PMCID: PMC9385729
- DOI: 10.1016/j.cld.2022.08.003
Abstract
The coronavirus disease-2019 (COVID-19) pandemic has had a large impact on patients with chronic liver disease (CLD) and liver transplantation (LT) recipients. Patients with advanced CLD are at a significantly increased risk of poor outcomes in the setting of severe acute respiratory syndrome coronavirus 2 infection. The pandemic has also considerably altered the management and care that is provided to patients with CLD, pre-LT patients, and LT recipients. Vaccination against COVID-19 protects patients with CLD and LT recipients from adverse outcomes and is safe in these patients; however, vaccine efficacy may be reduced in LT recipients and other immunosuppressed patients.
Keywords: Cirrhosis; Immunosuppression; SARS-CoV-2; Transplant; Vaccination.