Clin Infect Dis . Waning vaccine effectiveness against influenza-associated hospitalizations among adults, 2015-2016 to 2018-2019, US Hospitalized A

[tetano]

Clin Infect Dis


. 2021 Jan 19;ciab045.
doi: 10.1093/cid/ciab045. Online ahead of print.
Waning vaccine effectiveness against influenza-associated hospitalizations among adults, 2015-2016 to 2018-2019, US Hospitalized Adult Influenza Vaccine Effectiveness Network


Jill M Ferdinands[SUP] 1 [/SUP], Manjusha Gaglani[SUP] 2 [/SUP], Emily T Martin[SUP] 3 [/SUP], Arnold S Monto[SUP] 3 [/SUP], Donald Middleton[SUP] 4 [/SUP], Fernanda Silveira[SUP] 4 [/SUP], H Keipp Talbot[SUP] 5 [/SUP], Richard Zimmerman[SUP] 4 [/SUP], Manish Patel[SUP] 1 [/SUP]



Affiliations

• PMID: 33462610
• DOI: 10.1093/cid/ciab045

Abstract

We observed decreased effectiveness of influenza vaccine with increasing time since vaccination for prevention of influenza A(H3N2), influenza A(H1N1)pdm09, and influenza B(Yamagata)-associated hospitalizations among adults. Maximum VE was observed shortly after vaccination, followed by an absolute decline in VE of about 8 to 9% per month post-vaccination.

Keywords: adults; hospitalization; influenza; vaccine effectiveness; waning.