tetano
Editor, Senior Moderator
Clin Infect Dis
. 2022 Nov 3;ciac868.
doi: 10.1093/cid/ciac868. Online ahead of print.
Successful treatment of prolonged, severe COVID-19 lower respiratory tract disease in a B-cell ALL patient with an extended course of remdesivir and nirmatrelvir/ritonavir
Emily S Ford[SUP] 1 2 [/SUP], William Simmons[SUP] 1 [/SUP], Ellora N Karmarkar[SUP] 1 [/SUP], Leah H Yoke[SUP] 1 2 [/SUP], Ayodale B Braimah[SUP] 3 [/SUP], Johnnie J Orozco[SUP] 4 5 [/SUP], Cristina M Ghiuzeli[SUP] 4 6 [/SUP], Serena Barnhill[SUP] 7 [/SUP], Coralynn L Sack[SUP] 7 [/SUP], Joshua O Benditt[SUP] 7 [/SUP], Pavitra Roychoudhury[SUP] 2 8 [/SUP], Alexander L Greninger[SUP] 2 8 [/SUP], Adrienne E Shapiro[SUP] 1 2 9 [/SUP], Jennifer L Hammond[SUP] 10 [/SUP], James M Rusnak[SUP] 10 [/SUP], Mikael Dolsten[SUP] 10 [/SUP], Michael Boeckh[SUP] 1 2 4 [/SUP], Catherine Liu[SUP] 1 2 4 [/SUP], Guang-Shing Cheng[SUP] 2 4 7 [/SUP], Lawrence Corey[SUP] 1 2 4 8 [/SUP]
Affiliations
Abstract
A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, IV remdesivir and prolonged oral steroids. Twenty days of nirmatrelvir/ritonavir and 10 days of IV remdesivir led to full recovery.
. 2022 Nov 3;ciac868.
doi: 10.1093/cid/ciac868. Online ahead of print.
Successful treatment of prolonged, severe COVID-19 lower respiratory tract disease in a B-cell ALL patient with an extended course of remdesivir and nirmatrelvir/ritonavir
Emily S Ford[SUP] 1 2 [/SUP], William Simmons[SUP] 1 [/SUP], Ellora N Karmarkar[SUP] 1 [/SUP], Leah H Yoke[SUP] 1 2 [/SUP], Ayodale B Braimah[SUP] 3 [/SUP], Johnnie J Orozco[SUP] 4 5 [/SUP], Cristina M Ghiuzeli[SUP] 4 6 [/SUP], Serena Barnhill[SUP] 7 [/SUP], Coralynn L Sack[SUP] 7 [/SUP], Joshua O Benditt[SUP] 7 [/SUP], Pavitra Roychoudhury[SUP] 2 8 [/SUP], Alexander L Greninger[SUP] 2 8 [/SUP], Adrienne E Shapiro[SUP] 1 2 9 [/SUP], Jennifer L Hammond[SUP] 10 [/SUP], James M Rusnak[SUP] 10 [/SUP], Mikael Dolsten[SUP] 10 [/SUP], Michael Boeckh[SUP] 1 2 4 [/SUP], Catherine Liu[SUP] 1 2 4 [/SUP], Guang-Shing Cheng[SUP] 2 4 7 [/SUP], Lawrence Corey[SUP] 1 2 4 8 [/SUP]
Affiliations
- PMID: 36326680
- DOI: 10.1093/cid/ciac868
Abstract
A patient with B-cell acute lymphoblastic leukemia (ALL) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had persistent, progressive pneumonia with viremia after 5 months of infection despite monoclonal antibodies, IV remdesivir and prolonged oral steroids. Twenty days of nirmatrelvir/ritonavir and 10 days of IV remdesivir led to full recovery.