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Clin Infect Dis . Specific re-distribution of SARS-CoV-2 variants in the respiratory system and intestinal tract

tetano

Editor, Senior Moderator
Clin Infect Dis


. 2020 Oct 22;ciaa1617.
doi: 10.1093/cid/ciaa1617. Online ahead of print.
Specific re-distribution of SARS-CoV-2 variants in the respiratory system and intestinal tract


Pengcheng Du[SUP] 1 2 [/SUP], Chuan Song[SUP] 1 2 [/SUP], Rui Li[SUP] 1 2 [/SUP], Yangzi Song[SUP] 1 2 [/SUP], Jiarui Li[SUP] 1 2 [/SUP], Nan Ding[SUP] 1 2 [/SUP], Ju Zhang[SUP] 1 2 [/SUP], Rui Song[SUP] 3 [/SUP], Junyan Han[SUP] 1 2 [/SUP], Guiju Gao[SUP] 3 [/SUP], Jinglin Yue[SUP] 1 2 [/SUP], Ang Duan[SUP] 1 2 [/SUP], Yanyi Huang[SUP] 4 [/SUP], Jing An[SUP] 5 [/SUP], Jianbin Wang[SUP] 6 [/SUP], Fujie Zhang[SUP] 3 [/SUP], Chen Chen[SUP] 1 2 [/SUP], Hui Zeng[SUP] 1 2 [/SUP]



Affiliations

Abstract

Intra-host analysis of SARS-CoV-2 genomic sequences identified two viral haplotypes that comprised of three genetically linked mutations from the respiratory and intestinal tracts of a patient with COVID-19. Spatiotemporal data suggest that this patient initially had dual-infection of two SARS-CoV-2 variants, which subsequently re-distributed into the two systems.

Keywords: Severe acute respiratory syndrome coronavirus 2; dual-infection; organ specific re-distribution.
 
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