tetano
Editor, Senior Moderator
Clin Infect Dis. 2020 Apr 2. pii: ciaa375. doi: 10.1093/cid/ciaa375. [Epub ahead of print]
SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection.
Qiu L[SUP]1[/SUP], Liu X[SUP]1[/SUP], Xiao M[SUP]2[/SUP], Xie J[SUP]3[/SUP], Cao W[SUP]3[/SUP], Liu Z[SUP]3[/SUP], Morse A[SUP]4[/SUP], Xie Y[SUP]5[/SUP], Li T[SUP]3[/SUP], Zhu L[SUP]1[/SUP].
Author information
Abstract
BACKGROUND:
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is mainly spread through respiratory droplets or direct contact. But the infection condition of genital system is still unknown. This study aimed to evaluate whether or not SARS-CoV-2 is found in the vaginal fluid of women with COVID-19 illness.
METHODS:
10 women with confirmed severe COVID-19 pneumonia admitted to in Tongji Zhongfa Hospital Intensive care union(ICU) ward from Feb 4, 2020 to Feb 24, 2020 were included. Clinical records, laboratory results, and computer tomography(CT)-scan examination were retrospectively reviewed. The evidence of genital infection potential was accessed by testing for the presence of SARS-CoV-2 in vaginal fluids obtained from vaginal swab samples. Reverse transcriptase polymerase chain reaction(RT-PCR) was used to confirm the SARS-CoV-2 infection in vaginal fluids.
RESULTS:
The clinical characteristics of these ten women were similar to those reported severe COVID-19 patients. All ten patients were tested for SARS-CoV-2 in vaginal fluid, and all samples tested negative for the virus.
CONCLUSION:
Findings from this small group of cases suggest that no SARS-CoV-2 virus existing in the vaginal fluids of severe COVID-19 patients.
? The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
KEYWORDS:
COVID-19 pneumonia; SARS-CoV-2; clinical features; vaginal fluid
PMID:32241022DOI:10.1093/cid/ciaa375
SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection.
Qiu L[SUP]1[/SUP], Liu X[SUP]1[/SUP], Xiao M[SUP]2[/SUP], Xie J[SUP]3[/SUP], Cao W[SUP]3[/SUP], Liu Z[SUP]3[/SUP], Morse A[SUP]4[/SUP], Xie Y[SUP]5[/SUP], Li T[SUP]3[/SUP], Zhu L[SUP]1[/SUP].
Author information
Abstract
BACKGROUND:
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is mainly spread through respiratory droplets or direct contact. But the infection condition of genital system is still unknown. This study aimed to evaluate whether or not SARS-CoV-2 is found in the vaginal fluid of women with COVID-19 illness.
METHODS:
10 women with confirmed severe COVID-19 pneumonia admitted to in Tongji Zhongfa Hospital Intensive care union(ICU) ward from Feb 4, 2020 to Feb 24, 2020 were included. Clinical records, laboratory results, and computer tomography(CT)-scan examination were retrospectively reviewed. The evidence of genital infection potential was accessed by testing for the presence of SARS-CoV-2 in vaginal fluids obtained from vaginal swab samples. Reverse transcriptase polymerase chain reaction(RT-PCR) was used to confirm the SARS-CoV-2 infection in vaginal fluids.
RESULTS:
The clinical characteristics of these ten women were similar to those reported severe COVID-19 patients. All ten patients were tested for SARS-CoV-2 in vaginal fluid, and all samples tested negative for the virus.
CONCLUSION:
Findings from this small group of cases suggest that no SARS-CoV-2 virus existing in the vaginal fluids of severe COVID-19 patients.
? The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
KEYWORDS:
COVID-19 pneumonia; SARS-CoV-2; clinical features; vaginal fluid
PMID:32241022DOI:10.1093/cid/ciaa375