tetano
Editor, Senior Moderator
Clin Infect Dis
. 2022 Jun 23;ciac487.
doi: 10.1093/cid/ciac487. Online ahead of print.
SARS-CoV-2 co-detection with influenza A and other respiratory viruses among school-aged children and their household members- March 12, 2020, to February 22, 2022, Dane County, Wisconsin
Jonathan L Temte[SUP] 1 [/SUP], Shari Barlow[SUP] 1 [/SUP], Emily Temte[SUP] 1 [/SUP], Maureen Goss[SUP] 1 [/SUP], Allen Bateman[SUP] 2 [/SUP], Kelsey Florek[SUP] 2 [/SUP], Amra Uzicanin[SUP] 3 [/SUP]
Affiliations
Abstract
Background: Concurrent detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and another respiratory virus in individuals can document contemporaneous circulation. We used an ongoing, community-based study of school-aged children and their households to evaluate SARS-CoV-2 co-detections with other respiratory viruses in a non-medically attended population over a two-year period.
Methods: Household enrollment was predicated on an acute respiratory illness in a child residing in that household who was also a kindergarten through 12th grade student in the participating school district. Demographic, symptom and household composition data, and self-collected nasal specimens were obtained on the recruitment day, and 7 and 14 days later, from the index child and all other household members. All specimens were tested for SARS-CoV-2/influenza A/B by RT-PCR. Day 0 specimens from the index children were simultaneously tested for 17 viruses using a commercial respiratory pathogen panel (RPP). To assess viral co-detections involving SARS-CoV-2, all household specimens were tested via RPP if the index child's Day 0 specimen tested positive to any of the 17 viral targets in RPP and any household member tested positive for SARS-CoV-2.
Results: Of 2,109 participants (497 index children in 497 households with 1,612 additional household members), two (0.1%) were positive for both SARS-CoV-2 and influenza A; an additional 11 (0.5%) were positive for SARS-CoV-2 and another RPP-covered respiratory virus. Co-detections predominantly affected school-aged children (12 out of 13 total) and were noted in 11 of 497 households.
Conclusions: SARS-CoV-2 co-detections with other respiratory viruses were uncommon and predominated in school-aged children.
Keywords: SARS-CoV-2; children; co-detection; households; respiratory viruses.
. 2022 Jun 23;ciac487.
doi: 10.1093/cid/ciac487. Online ahead of print.
SARS-CoV-2 co-detection with influenza A and other respiratory viruses among school-aged children and their household members- March 12, 2020, to February 22, 2022, Dane County, Wisconsin
Jonathan L Temte[SUP] 1 [/SUP], Shari Barlow[SUP] 1 [/SUP], Emily Temte[SUP] 1 [/SUP], Maureen Goss[SUP] 1 [/SUP], Allen Bateman[SUP] 2 [/SUP], Kelsey Florek[SUP] 2 [/SUP], Amra Uzicanin[SUP] 3 [/SUP]
Affiliations
- PMID: 35737942
- DOI: 10.1093/cid/ciac487
Abstract
Background: Concurrent detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and another respiratory virus in individuals can document contemporaneous circulation. We used an ongoing, community-based study of school-aged children and their households to evaluate SARS-CoV-2 co-detections with other respiratory viruses in a non-medically attended population over a two-year period.
Methods: Household enrollment was predicated on an acute respiratory illness in a child residing in that household who was also a kindergarten through 12th grade student in the participating school district. Demographic, symptom and household composition data, and self-collected nasal specimens were obtained on the recruitment day, and 7 and 14 days later, from the index child and all other household members. All specimens were tested for SARS-CoV-2/influenza A/B by RT-PCR. Day 0 specimens from the index children were simultaneously tested for 17 viruses using a commercial respiratory pathogen panel (RPP). To assess viral co-detections involving SARS-CoV-2, all household specimens were tested via RPP if the index child's Day 0 specimen tested positive to any of the 17 viral targets in RPP and any household member tested positive for SARS-CoV-2.
Results: Of 2,109 participants (497 index children in 497 households with 1,612 additional household members), two (0.1%) were positive for both SARS-CoV-2 and influenza A; an additional 11 (0.5%) were positive for SARS-CoV-2 and another RPP-covered respiratory virus. Co-detections predominantly affected school-aged children (12 out of 13 total) and were noted in 11 of 497 households.
Conclusions: SARS-CoV-2 co-detections with other respiratory viruses were uncommon and predominated in school-aged children.
Keywords: SARS-CoV-2; children; co-detection; households; respiratory viruses.