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Clin Infect Dis . Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2

tetano

Editor, Senior Moderator
Clin Infect Dis


. 2022 Jul 5;ciac553.
doi: 10.1093/cid/ciac553. Online ahead of print.
Lower Risk of Multisystem Inflammatory Syndrome in Children (MIS-C) with the Delta and Omicron variants of SARS-CoV-2


Jonathan M Cohen[SUP] 1 2 [/SUP], Michael J Carter[SUP] 3 4 [/SUP], C Ronny Cheung[SUP] 5 6 [/SUP], Shamez Ladhani[SUP] 7 8 [/SUP], Evelina PIMS-TS Study Group



Affiliations

Abstract

Little is known about the MIS-C risk with different SARS-CoV-2 variants. In Southeast England, MIS-C rates per confirmed SARS-CoV-2 infections in 0-16 years-olds were 56% lower (rate ratio, 0.34; 95%CI, 0.23-0.50) during pre-vaccine Delta, 66% lower (0.44; 0.28-0.69) during post-vaccine Delta and 95% lower (0.05; 0.02-0.10) during the Omicron period.

Keywords: COVID-19; MIS-C; PIMS-TS; SARS-CoV-2; coronavirus.
 
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