Clin.Infect.Dis. Fetal Infection by Zika Virus in the Third Trimester: Report of 2 Cases

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[h=1]Fetal Infection by Zika Virus in the Third Trimester: Report of 2 Cases[/h]

• Antonio Soares de Souza1,2,
• Cristiane Moraes Dias2,
• Fernanda Del Campo Braojos Braga2,
• Ana Carolina Bernardes Terzian3,
• C?ssia Fernanda Estofolete3,
• Antonio H?lio Oliani4,
• Gustavo Henrique Oliveira2,
• Cinara C?ssia Brand?o de Mattos5,
• Luiz Carlos de Mattos5,
• Maur?cio Lacerda Nogueira3, and
• Denise Cristina M?s Vaz-Oliani2,4

+ Author Affiliations

• [SUP]1[/SUP]Department of Radiology, Faculdade de Medicina de S?o Jos? do Rio Preto (FAMERP)
• [SUP]2[/SUP]Hospital da Crian?a e Maternidade
• [SUP]3[/SUP]Laboratory of Virology, Department of Infectious and Dermatological Disease
• [SUP]4[/SUP]Department of Obstetrics and Gynecology
• [SUP]5[/SUP]Immunogenetics Laboratory, Department of Molecular Biology, FAMERP, S?o Jos? do Rio Preto, S?o Paulo, Brazil

• Correspondence: M. L. Nogueira, Laboratory of Virology, Faculdade de Medicina de S?o Jos? do Rio Preto, Avenida Brigadeiro Faria Lima, 5416, 15090-000 ? S?o Jos? do Rio Preto, SP, Brazil (mnogueira@famerp.br).

[h=2]Abstract[/h] Zika virus (ZIKV) infection acquired during pregnancy is associated with congenital microcephaly. We describe 2 cases of ZIKV infection in women in their 36th week of pregnancy whose fetuses had preserved head circumference at birth and findings of subependymal cysts and lenticulostriate vasculopathy in postnatal imaging. These represent the first signs of congenital brain injury acquired due to ZIKV in the third trimester.

http://cid.oxfordjournals.org/content/early/2016/10/02/cid.ciw613.abstract