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Clin Infect Dis. Effectiveness of non-adjuvanted monovalent A(H1N1)pdm09 vaccines for preventing RT-PCR-confirmed pandemic influenza hospitalizations:

Giuseppe

Emeritus
[Source: Clinical Infectious Diseases Journal, full page: (LINK). Abstract, edited.]


Effectiveness of non-adjuvanted monovalent A(H1N1)pdm09 vaccines for preventing RT-PCR-confirmed pandemic influenza hospitalizations: Case-control study of children and adults at ten U.S. Influenza Surveillance Network sites


Mark Thompson 1,*, Leslie Z. Sokolow 1,2,**, Olivia Almendares 3,4, Kyle Openo 3,4, Monica M. Farley 3,5, James Meek 6, Julie Ray 6, Pamala Daily Kirley 7, Arthur Reingold 8, Deborah Aragon 9, Emily Hancock 10, Joan Baumbach 10, William Schaffner 11,12, Ruth Lynfield 15, Pat Ryan 14, Maya Monroe 14, Po-Yung Cheng 1,2, Alicia Fry 1, and David K. Shay 1

Author Affiliations: <SUP>1</SUP>Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia <SUP>2</SUP>Battelle Memorial Institute, Atlanta, Georgia <SUP>3</SUP>Atlanta VA Medical Center, Atlanta, Georgia <SUP>4</SUP>Atlanta Research and Education Foundation, Atlanta, Georgia <SUP>5</SUP>Emory University School of Medicine <SUP>6</SUP>Connecticut Emerging Infections Program, New Haven, Connecticut <SUP>7</SUP>California Emerging Infections Program, Oakland, California <SUP>8</SUP>Department of Epidemiology, School of Public Health, University of California, Berkeley, California <SUP>9</SUP>Colorado Department of Public Health and Environment, Denver, Colorado <SUP>10</SUP>New Mexico Emerging Infections Program, Santa Fe, New Mexico <SUP>11</SUP>Tennessee Department of Health, Nashville, Tennessee <SUP>12</SUP>Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee <SUP>14</SUP>Maryland Department of Health and Mental Hygiene, Baltimore, Maryland <SUP>15</SUP>Minnesota Department of Health, St. Paul, Minnesota

*Primary corresponding author: Influenza Division, MS-A32, 1600 Clifton Rd., Atlanta GA 30333; telephone: (404) 583-5737; email: isq8@cdc.gov.

** Secondary corresponding author: Same address; telephone: (404) 639-1720; email: bkk5@cdc.gov.


Abstract

During 2009-2010, we examined 217 cases hospitalized with laboratory-confirmed pandemic influenza in nine FluSurv-NET sites and 413 age- and community-matched controls and found a single dose of monovalent non-adjuvanted influenza A(H1N1)pdm09 vaccine was 50% (95% CI=13%?71%) effective in preventing hospitalization associated with A(H1N1)pdm09 virus infection.


Received May 28, 2013. Accepted August 11, 2013.

Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2013.

<CITE><ABBR>Clin Infect Dis.</ABBR> (2013) doi: 10.1093/cid/cit551 </CITE>First published online: August 15, 2013


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