tetano
Editor, Senior Moderator
Clin Imaging
. 2020 May 16.
doi: 10.1016/j.clinimag.2020.05.016. Online ahead of print.
CT Imaging Features of 34 Patients Infected With COVID-19
Litao Zhang[SUP] 1 [/SUP], Xue Kong[SUP] 2 [/SUP], Xiujuan Li[SUP] 1 [/SUP], Jianzhong Zhu[SUP] 3 [/SUP], Shanping Liu[SUP] 4 [/SUP], Weiwei Li[SUP] 5 [/SUP], Chunlin Xu[SUP] 6 [/SUP], Huanwang Du[SUP] 7 [/SUP], Hui Jing[SUP] 8 [/SUP], Jiahuan Xu[SUP] 1 [/SUP], Tongtong Shi[SUP] 1 [/SUP], Yuanzhong Xie[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: To retrospectively analyze the CT findings in patients infected with Coronavirus disease 2019 (COVID-19).
Materials and methods: The thirty-four cases, 15 females and 19 males, with an age ranging from 7 to 88 years old, confirmed by real-time reverse-transcriptase-polymerase chain reaction (RT-PCR), were used for our study. All thin-section CT scans of the lungs were performed in all of patients. The clinical, laboratory and CT imaging were available to evaluate in all patients.
Results: The patients present with fever (85.29%, n = 29), cough (67.65%, n = 23), fatigue or myalgia (26.47%, n = 9), and pharyngalgia (8.82%, n = 3). The 4 patients (11.76%) with no symptoms were identified during screening for close contacts, who had typical CT findings. On initial CT scans, the bilateral lung involved was shown in 24 cases (70.59%), while 29 (82.35%) cases were distributed in peripheral. The pure ground glass opacity (GGO) was shown in 18 cases (52.94%), the GGO with consolidation was in 12 cases (35.29%), and full consolidation only in 3 cases. The lesion with air bronchogram was seen in 14 (41.18%) cases, with enlarged blood vessel in 17 (50.00%) cases, with crazy-paving pattern in 8 (23.53%) cases, with fine reticular pattern in 4 (11.77%) cases, and with intralesional vacuole sign in 6 (17.65%) cases. The pleural effusion was seen in one patient. Follow-up imaging in 19 patients during the study time window demonstrated mild, moderate or severe progression of disease, as manifested by increasing extent and density of lung opacities.
Conclusions: The bilateral GGO with air bronchogram, enlarged blood vessel, fine reticular pattern, and peripheral distribution are the early CT findings of COVID-19. The crazy-paving pattern and intralesional vacuole sign are the features of progressive stage.
Keywords: COVID-19; CT; Consolidation; Crazy-paving pattern; Ground glass opacity.
. 2020 May 16.
doi: 10.1016/j.clinimag.2020.05.016. Online ahead of print.
CT Imaging Features of 34 Patients Infected With COVID-19
Litao Zhang[SUP] 1 [/SUP], Xue Kong[SUP] 2 [/SUP], Xiujuan Li[SUP] 1 [/SUP], Jianzhong Zhu[SUP] 3 [/SUP], Shanping Liu[SUP] 4 [/SUP], Weiwei Li[SUP] 5 [/SUP], Chunlin Xu[SUP] 6 [/SUP], Huanwang Du[SUP] 7 [/SUP], Hui Jing[SUP] 8 [/SUP], Jiahuan Xu[SUP] 1 [/SUP], Tongtong Shi[SUP] 1 [/SUP], Yuanzhong Xie[SUP] 1 [/SUP]
Affiliations
- PMID: 32425337
- PMCID: PMC7229931
- DOI: 10.1016/j.clinimag.2020.05.016
Abstract
Objective: To retrospectively analyze the CT findings in patients infected with Coronavirus disease 2019 (COVID-19).
Materials and methods: The thirty-four cases, 15 females and 19 males, with an age ranging from 7 to 88 years old, confirmed by real-time reverse-transcriptase-polymerase chain reaction (RT-PCR), were used for our study. All thin-section CT scans of the lungs were performed in all of patients. The clinical, laboratory and CT imaging were available to evaluate in all patients.
Results: The patients present with fever (85.29%, n = 29), cough (67.65%, n = 23), fatigue or myalgia (26.47%, n = 9), and pharyngalgia (8.82%, n = 3). The 4 patients (11.76%) with no symptoms were identified during screening for close contacts, who had typical CT findings. On initial CT scans, the bilateral lung involved was shown in 24 cases (70.59%), while 29 (82.35%) cases were distributed in peripheral. The pure ground glass opacity (GGO) was shown in 18 cases (52.94%), the GGO with consolidation was in 12 cases (35.29%), and full consolidation only in 3 cases. The lesion with air bronchogram was seen in 14 (41.18%) cases, with enlarged blood vessel in 17 (50.00%) cases, with crazy-paving pattern in 8 (23.53%) cases, with fine reticular pattern in 4 (11.77%) cases, and with intralesional vacuole sign in 6 (17.65%) cases. The pleural effusion was seen in one patient. Follow-up imaging in 19 patients during the study time window demonstrated mild, moderate or severe progression of disease, as manifested by increasing extent and density of lung opacities.
Conclusions: The bilateral GGO with air bronchogram, enlarged blood vessel, fine reticular pattern, and peripheral distribution are the early CT findings of COVID-19. The crazy-paving pattern and intralesional vacuole sign are the features of progressive stage.
Keywords: COVID-19; CT; Consolidation; Crazy-paving pattern; Ground glass opacity.