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Clin Imaging . Brain MRI findings in COVID-19 patients with PRES: A systematic review

tetano

Editor, Senior Moderator
Clin Imaging


. 2021 Oct 16;81:107-113.
doi: 10.1016/j.clinimag.2021.10.003. Online ahead of print.
Brain MRI findings in COVID-19 patients with PRES: A systematic review


Rubaya Yeahia[SUP] 1 [/SUP], Javin Schefflein[SUP] 2 [/SUP], Patrick Chiarolanzio[SUP] 3 [/SUP], Anna Rozenstein[SUP] 4 [/SUP], William Gomes[SUP] 2 [/SUP], Sana Ali[SUP] 2 [/SUP], Hasit Mehta[SUP] 2 [/SUP], Fawaz Al-Mufti[SUP] 5 [/SUP], Andrew McClelland[SUP] 6 [/SUP], Edwin Gulko[SUP] 7 [/SUP]



Affiliations

Abstract

Background: Numerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES).
Purpose: We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES.
Methods: PubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES.
Results: Twenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively.
Conclusions: PRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.

Keywords: COVID-19; MRI brain; PRES.
 
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