tetano
Editor, Senior Moderator
Clin Exp Hypertens
. 2022 May 8;1-8.
doi: 10.1080/10641963.2022.2071914. Online ahead of print.
Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis
Zhe Qian[SUP] 1 [/SUP], Zhuohong Li[SUP] 1 [/SUP], Jie Peng[SUP] 1 [/SUP], Qiqing Gao[SUP] 1 [/SUP], Shaohang Cai[SUP] 1 [/SUP], Xuwen Xu[SUP] 1 [/SUP]
Affiliations
Abstract
Background: To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia.
Methods: We implemented a systematic search of PubMed for articles that assessed clinical outcomes of hypertensive patients infected with SARS-CoV-2. The primary outcomes evaluated included: in-hospital mortality, ICU admission, and the use of invasive ventilation.
Results: A total of 18 studies were included, involving 13,293 patients and covering from January 25, 2020, to April 20, 2020. The relationship between hypertension and prognosis in COVID-19 patients was evaluated. Results showed that hypertension was a risk factor for in-hospital mortality in COVID-19 patients (RR: 2.20, 95% CI, 1.83-2.65, P < .001). Moreover, patients with hypertension were more likely to be admitted to ICU (RR: 1.86, 95% CI, 1.13-3.07, P = .001) and to use invasive ventilation (RR: 2.99, 95% CI, 1.73-5.17, P < .001).
Conclusions: Among COVID-19 patients, those combined with hypertension had a significantly higher risk of in-hospital deaths, admission to ICU, and need for invasive ventilation.
Keywords: COVID-19; epidemiology; hypertension; respiratory infections; virology.
. 2022 May 8;1-8.
doi: 10.1080/10641963.2022.2071914. Online ahead of print.
Association between hypertension and prognosis of patients with COVID-19: A systematic review and meta-analysis
Zhe Qian[SUP] 1 [/SUP], Zhuohong Li[SUP] 1 [/SUP], Jie Peng[SUP] 1 [/SUP], Qiqing Gao[SUP] 1 [/SUP], Shaohang Cai[SUP] 1 [/SUP], Xuwen Xu[SUP] 1 [/SUP]
Affiliations
- PMID: 35531646
- DOI: 10.1080/10641963.2022.2071914
Abstract
Background: To investigate the association between hypertension and clinical outcomes, including in-hospital mortality, intensive care unit (ICU) admission, and invasive ventilation in patients with coronavirus disease 2019 (COVID-19) pneumonia.
Methods: We implemented a systematic search of PubMed for articles that assessed clinical outcomes of hypertensive patients infected with SARS-CoV-2. The primary outcomes evaluated included: in-hospital mortality, ICU admission, and the use of invasive ventilation.
Results: A total of 18 studies were included, involving 13,293 patients and covering from January 25, 2020, to April 20, 2020. The relationship between hypertension and prognosis in COVID-19 patients was evaluated. Results showed that hypertension was a risk factor for in-hospital mortality in COVID-19 patients (RR: 2.20, 95% CI, 1.83-2.65, P < .001). Moreover, patients with hypertension were more likely to be admitted to ICU (RR: 1.86, 95% CI, 1.13-3.07, P = .001) and to use invasive ventilation (RR: 2.99, 95% CI, 1.73-5.17, P < .001).
Conclusions: Among COVID-19 patients, those combined with hypertension had a significantly higher risk of in-hospital deaths, admission to ICU, and need for invasive ventilation.
Keywords: COVID-19; epidemiology; hypertension; respiratory infections; virology.
