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Climacteric . Women and COVID-19: severity and mortality in hospitalized middle-aged and older patients

tetano

Editor, Senior Moderator
Climacteric


. 2021 Jan 29;1-6.
doi: 10.1080/13697137.2020.1868424. Online ahead of print.
Women and COVID-19: severity and mortality in hospitalized middle-aged and older patients


L Balc?zar-Hern?ndez[SUP] 1 2 3 [/SUP], C Mart?nez-Murillo[SUP] 1 [/SUP], C Ramos-Pe?afiel[SUP] 1 4 5 [/SUP], K Pell?n Tellez[SUP] 1 [/SUP], B Li[SUP] 1 [/SUP], L Manuel-Apolinar[SUP] 2 [/SUP], L Basurto[SUP] 2 [/SUP]



Affiliations

Abstract

Objective: The aim of the study was to evaluate the clinical features, severity, and mortality of coronavirus disease-2019 (COVID-19) in hospitalized middle-aged and older women, and the risk factors associated with severity and mortality in women.
Methods: A retrospective study was conducted in hospitalized patients with COVID-19. The clinical features, severity, and mortality of COVID-19 in middle-aged and older women (age 45 years and older) were compared to those of younger women (age <45 years).
Results: A higher frequency of hypertension, invasive mechanical ventilation (IMV) requirement, and mortality was evidenced in middle-aged and older women. Age ≥45 years (odds ratio 2.7; 95% confidence interval 1.21-6.27; p = 0.01) and IMV requirement (odds ratio 3.0; 95% confidence interval 1.34-6.76; p = 0.004) predicted mortality.
Conclusions: Severity and mortality are higher in middle-aged and older women with COVID-19 compared to younger women.

Keywords: COVID-19; mortality; severity; women.
 
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