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Circulation of Antibodies Against Influenza Virus Hemagglutinins in the 2014/2015 Epidemic Season in Poland

tetano

Editor, Senior Moderator
Adv Exp Med Biol. 2017 Feb 9. doi: 10.1007/5584_2016_191. [Epub ahead of print]
[h=1]Circulation of Antibodies Against Influenza Virus Hemagglutinins in the 2014/2015 Epidemic Season in Poland.[/h] Kowalczyk D[SUP]1[/SUP], Szymański K[SUP]2[/SUP], Cieślak K[SUP]2[/SUP], Brydak LB[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] The aim of this study was to determine the level of anti-hemagglutinin antibodies in the serum of people in different age-groups during the 2014/2015 epidemic influenza season in Poland. A total of 1050 sera were tested. The level of anti-hemagglutinin antibodies was determined using the hemagglutinin inhibition test. The results provided information on the incidence of circulating A/California/7/2009(H1N1)pdm09, A/Texas/50/2012(H3N2), and B/Massachusetts/2/2012 viruses. The level of antibodies against influenza differed between age-groups. The protection rate was the highest for the antigen B/Massachusetts/2/2012, with the decreasing order of values in the following age-groups: ≥65 years (76.7 %), 15-25 years (72.7 %), and 0-4 years (62.0 %). The average values of the protection rate in other age-groups were as follows: 43.3 % in 22-64 years, 40% in 5-9 years, and 39.3 % in 45-64 years of age, while the lowest value of 22.7 % was in 10-14 years old subjects. In the 2014/2015 epidemic season in Poland only were 3.6 % of the population vaccinated. That is why the presented results could be interpreted as a response of the immune system of patients after infection caused by influenza virus.


[h=4]KEYWORDS:[/h] Age; Antibodies; Hemagglutinin inhibition test; Influenza; Protection rate; Vaccination

PMID: 28181197 DOI: 10.1007/5584_2016_191
[PubMed - as supplied by publisher]
 
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