tetano
Editor, Senior Moderator
Circ Rep
. 2024 May 9;6(6):191-200.
doi: 10.1253/circrep.CR-24-0011. eCollection 2024 Jun 10. Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on the Severity and the Mortality of Acute Myocardial Infarction in Japan - Analysis From the JROAD-DPC Database
Mitsukuni Kimura[SUP] 1 [/SUP], Tetsuya Matoba[SUP] 1 [/SUP], Yasuhiro Nakano[SUP] 1 [/SUP], Shunsuke Katsuki[SUP] 1 [/SUP], Kazuo Sakamoto[SUP] 1 [/SUP], Masaaki Nishihara[SUP] 1 [/SUP], Takuya Nagata[SUP] 1 [/SUP], Yoshio Tahara[SUP] 2 [/SUP], Ken Nagao[SUP] 3 [/SUP], Hiroyuki Okura[SUP] 4 [/SUP], Takanori Ikeda[SUP] 5 [/SUP], Michikazu Nakai[SUP] 6 [/SUP], Hiroyuki Tsutsui[SUP] 1 [/SUP]
Affiliations
Background: Coronavirus disease 2019 (COVID-19) has impacted on cardiovascular disease. However, it remains unclear whether the COVID-19 pandemic has impacted on disease severity and patients' prognosis of acute myocardial infarction (AMI) in Japan. Methods and Results: We retrospectively accumulated data from the Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination (JROAD-DPC) study (April 2019 to March 2021). Patients were divided into a before COVID-19 pandemic group or a during COVID-19 pandemic group. The proportion of patients who presented with cardiogenic shock (Killip class IV) was compared between groups, in association with 30-day mortality as the primary outcome. Killip class IV AMI significantly increased in the during COVID-19 pandemic group (15.7% vs. 14.5% in the before pandemic group, P<0.0001). The 30-day mortality was higher in the during COVID-19 pandemic group (9.6% vs. 9.2% in the before COVID-19 pandemic group, P=0.049). However, there was no significant difference in the adjusted 30-day mortality in each Killip class between the before and during COVID-19 pandemic groups. Conclusions: During the early stage of the COVID-19 pandemic in Japan, 30-day mortality of AMI increased, mainly because of the increase of Killip class IV AMI patients. However, irrespective of the COVID-19 pandemic, the adjusted 30-day mortality of each Killip classification group was unchanged.
Keywords: Acute coronary syndrome; Acute myocardial infarction; Cardiovascular disease.
. 2024 May 9;6(6):191-200.
doi: 10.1253/circrep.CR-24-0011. eCollection 2024 Jun 10. Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on the Severity and the Mortality of Acute Myocardial Infarction in Japan - Analysis From the JROAD-DPC Database
Mitsukuni Kimura[SUP] 1 [/SUP], Tetsuya Matoba[SUP] 1 [/SUP], Yasuhiro Nakano[SUP] 1 [/SUP], Shunsuke Katsuki[SUP] 1 [/SUP], Kazuo Sakamoto[SUP] 1 [/SUP], Masaaki Nishihara[SUP] 1 [/SUP], Takuya Nagata[SUP] 1 [/SUP], Yoshio Tahara[SUP] 2 [/SUP], Ken Nagao[SUP] 3 [/SUP], Hiroyuki Okura[SUP] 4 [/SUP], Takanori Ikeda[SUP] 5 [/SUP], Michikazu Nakai[SUP] 6 [/SUP], Hiroyuki Tsutsui[SUP] 1 [/SUP]
Affiliations
- PMID: 38860181
- PMCID: PMC11162853
- DOI: 10.1253/circrep.CR-24-0011
Background: Coronavirus disease 2019 (COVID-19) has impacted on cardiovascular disease. However, it remains unclear whether the COVID-19 pandemic has impacted on disease severity and patients' prognosis of acute myocardial infarction (AMI) in Japan. Methods and Results: We retrospectively accumulated data from the Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination (JROAD-DPC) study (April 2019 to March 2021). Patients were divided into a before COVID-19 pandemic group or a during COVID-19 pandemic group. The proportion of patients who presented with cardiogenic shock (Killip class IV) was compared between groups, in association with 30-day mortality as the primary outcome. Killip class IV AMI significantly increased in the during COVID-19 pandemic group (15.7% vs. 14.5% in the before pandemic group, P<0.0001). The 30-day mortality was higher in the during COVID-19 pandemic group (9.6% vs. 9.2% in the before COVID-19 pandemic group, P=0.049). However, there was no significant difference in the adjusted 30-day mortality in each Killip class between the before and during COVID-19 pandemic groups. Conclusions: During the early stage of the COVID-19 pandemic in Japan, 30-day mortality of AMI increased, mainly because of the increase of Killip class IV AMI patients. However, irrespective of the COVID-19 pandemic, the adjusted 30-day mortality of each Killip classification group was unchanged.
Keywords: Acute coronary syndrome; Acute myocardial infarction; Cardiovascular disease.