tetano
Editor, Senior Moderator
Circ J
. 2021 May 13.
doi: 10.1253/circj.CJ-21-0243. Online ahead of print.
Multisystem Inflammatory Syndrome in Children - A New Syndrome Complicated With Acute Heart Failure Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
Momoko Uchida[SUP] 1 [/SUP], Yuichiro Kashima[SUP] 1 [/SUP], Katsunori Mochizuki[SUP] 1 [/SUP], Hiroto Sakamoto[SUP] 1 [/SUP], Kotaro Mori[SUP] 1 [/SUP], Soichiro Ebisawa[SUP] 2 [/SUP], Kanako Takeshige[SUP] 1 [/SUP], Kenichi Nitta[SUP] 1 [/SUP], Koichiro Kuwahara[SUP] 2 [/SUP], Hiroshi Imamura[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Multisystem inflammatory syndrome in children (MIS-C) is a rare syndrome temporally related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MIS-C shares similarities with Kawasaki disease, but left ventricular dysfunction is more common in MIS-C.Methods and Results:This study reports the case of a 16-year-old Japanese male patient with MIS-C. Although the initial presentation was severe with circulatory and respiratory failure, the patient recovered completely. Endomyocardial biopsy showed active myocarditis with fibrosis. Immunoglobulin treatment was useful for recovery.
Conclusions: This is the first reported case of MIS-C in Japan. Cardiologists should be aware of MIS-C, a new disease, occurring during the global SARS-CoV-2 pandemic.
Keywords: Multisystem inflammatory syndrome in children (MIS-C); Myocarditis; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
. 2021 May 13.
doi: 10.1253/circj.CJ-21-0243. Online ahead of print.
Multisystem Inflammatory Syndrome in Children - A New Syndrome Complicated With Acute Heart Failure Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
Momoko Uchida[SUP] 1 [/SUP], Yuichiro Kashima[SUP] 1 [/SUP], Katsunori Mochizuki[SUP] 1 [/SUP], Hiroto Sakamoto[SUP] 1 [/SUP], Kotaro Mori[SUP] 1 [/SUP], Soichiro Ebisawa[SUP] 2 [/SUP], Kanako Takeshige[SUP] 1 [/SUP], Kenichi Nitta[SUP] 1 [/SUP], Koichiro Kuwahara[SUP] 2 [/SUP], Hiroshi Imamura[SUP] 1 [/SUP]
Affiliations
- PMID: 33980782
- DOI: 10.1253/circj.CJ-21-0243
Abstract
Background: Multisystem inflammatory syndrome in children (MIS-C) is a rare syndrome temporally related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). MIS-C shares similarities with Kawasaki disease, but left ventricular dysfunction is more common in MIS-C.Methods and Results:This study reports the case of a 16-year-old Japanese male patient with MIS-C. Although the initial presentation was severe with circulatory and respiratory failure, the patient recovered completely. Endomyocardial biopsy showed active myocarditis with fibrosis. Immunoglobulin treatment was useful for recovery.
Conclusions: This is the first reported case of MIS-C in Japan. Cardiologists should be aware of MIS-C, a new disease, occurring during the global SARS-CoV-2 pandemic.
Keywords: Multisystem inflammatory syndrome in children (MIS-C); Myocarditis; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).