Shiloh
Editor, Senior Moderator
Source: http://www.cidrap.umn.edu/news-perspective/2019/08/stewardship-resistance-scan-aug-14-2019
Stewardship / Resistance Scan for Aug 14, 2019
Antibiotic resistance legislation; Urinary tract infection treatment
Filed Under:
Antimicrobial Stewardship
[h=3]Ohio senator reintroduces antibiotic resistance legislation[/h] US Sen. Sherrod Brown, D-Ohio, yesterday reintroduced legislation to strengthen the federal government's response to antibiotic resistance.
Brown's bill, the Strategies to Address Antibiotic Resistance (STAAR) Act, emphasizes enhanced data collection and increased federal investment in efforts to monitor, prevent, and control drug-resistant pathogens. It would reauthorize the Interagency Antimicrobial Resistance Task Force, codify sections of the National Action Plan for Combating Antibiotic-Resistant Bacteria, enact key Centers for Disease Control and Prevention (CDC) recommendations for bolstering federal surveillance, prevention, control, and research efforts, and allow the CDC to partner with state health departments to implement prevention collaboratives.
The legislation also calls for the federal government to authorize the use of grants to healthcare facilities to study the development and implementation of antimicrobial stewardship programs.
"Antibiotics do a world of good for Ohioans fighting infections and illness, but now antibiotics are becoming less effective, putting people at risk from dangerous infections that can't be cured," Brown said in a press release. "We should address this growing crisis head on, both to stop the spread of deadly superbugs and to preserve antibiotics as a tool to fight disease."
Aug 12 Sen. Brown press release
[h=3]British study finds opportunities to improve prescribing for UTIs[/h] A study of patients diagnosed with lower urinary tract infections (UTIs) in England has found that more than 85% receive antibiotics on the day they were diagnosed, and 83% had no record of a urine sample collection, researchers from the University of Leeds reported in EClinicalMedicine.
Using a large healthcare research database containing records from English primary care practices, the researchers examined data on patients diagnosed with a lower UTI from 2011 through 2015 at 390 practices. They looked specifically at UTI investigation, antibiotic treatment, and antibiotic re-prescription within 28 days according to guideline-defined patient groups, and assessed risk factors for re-prescription.
During the study period, a total of 494,675 lower UTI episodes were diagnosed in 300,354 patients, 83.3% of whom were women. Antibiotics were prescribed on the same day of diagnosis for 85.7% of UTIs, and only 17% of those who received antibiotics had a recorded urine test within 10 days of diagnosis. The most common antibiotics initially prescribed were trimethoprim (56.8%) and nitrofurantoin (23.9%).
The antibiotic re-prescription rate was low (4.1%), increasing slightly over time in men (from 5.2% in 2011 to 6.2% in 2015), and 21.1% of re-prescriptions were for the same antibiotic. The risk of antibiotic re-prescription increased with age, calendar year, recent antibiotic prescribing, and treatment with antibiotic other than trimethoprim or nitrofurantoin.
The authors of the study say the results?the high proportion of same-day antibiotic treatment, lack of microbiological investigation, lack of diversity in antibiotic treatment, and the proportion of re-prescriptions for the same antibiotic as was initially prescribed?present several opportunities to optimize antibiotic prescribing for UTIs that could potentially reduce the risk of antibiotic resistance.
Aug 12 EClinicalMedicine study
Stewardship / Resistance Scan for Aug 14, 2019
Antibiotic resistance legislation; Urinary tract infection treatment
Filed Under:
Antimicrobial Stewardship
[h=3]Ohio senator reintroduces antibiotic resistance legislation[/h] US Sen. Sherrod Brown, D-Ohio, yesterday reintroduced legislation to strengthen the federal government's response to antibiotic resistance.
Brown's bill, the Strategies to Address Antibiotic Resistance (STAAR) Act, emphasizes enhanced data collection and increased federal investment in efforts to monitor, prevent, and control drug-resistant pathogens. It would reauthorize the Interagency Antimicrobial Resistance Task Force, codify sections of the National Action Plan for Combating Antibiotic-Resistant Bacteria, enact key Centers for Disease Control and Prevention (CDC) recommendations for bolstering federal surveillance, prevention, control, and research efforts, and allow the CDC to partner with state health departments to implement prevention collaboratives.
The legislation also calls for the federal government to authorize the use of grants to healthcare facilities to study the development and implementation of antimicrobial stewardship programs.
"Antibiotics do a world of good for Ohioans fighting infections and illness, but now antibiotics are becoming less effective, putting people at risk from dangerous infections that can't be cured," Brown said in a press release. "We should address this growing crisis head on, both to stop the spread of deadly superbugs and to preserve antibiotics as a tool to fight disease."
Aug 12 Sen. Brown press release
[h=3]British study finds opportunities to improve prescribing for UTIs[/h] A study of patients diagnosed with lower urinary tract infections (UTIs) in England has found that more than 85% receive antibiotics on the day they were diagnosed, and 83% had no record of a urine sample collection, researchers from the University of Leeds reported in EClinicalMedicine.
Using a large healthcare research database containing records from English primary care practices, the researchers examined data on patients diagnosed with a lower UTI from 2011 through 2015 at 390 practices. They looked specifically at UTI investigation, antibiotic treatment, and antibiotic re-prescription within 28 days according to guideline-defined patient groups, and assessed risk factors for re-prescription.
During the study period, a total of 494,675 lower UTI episodes were diagnosed in 300,354 patients, 83.3% of whom were women. Antibiotics were prescribed on the same day of diagnosis for 85.7% of UTIs, and only 17% of those who received antibiotics had a recorded urine test within 10 days of diagnosis. The most common antibiotics initially prescribed were trimethoprim (56.8%) and nitrofurantoin (23.9%).
The antibiotic re-prescription rate was low (4.1%), increasing slightly over time in men (from 5.2% in 2011 to 6.2% in 2015), and 21.1% of re-prescriptions were for the same antibiotic. The risk of antibiotic re-prescription increased with age, calendar year, recent antibiotic prescribing, and treatment with antibiotic other than trimethoprim or nitrofurantoin.
The authors of the study say the results?the high proportion of same-day antibiotic treatment, lack of microbiological investigation, lack of diversity in antibiotic treatment, and the proportion of re-prescriptions for the same antibiotic as was initially prescribed?present several opportunities to optimize antibiotic prescribing for UTIs that could potentially reduce the risk of antibiotic resistance.
Aug 12 EClinicalMedicine study