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CIDRAP- NEWS BRIEFS October 23, 2025

Lance

MPH, CSP & CIT Retired, CHMM Emeritus
https://www.cidrap.umn.edu/all-news

Quick takes: Disappointing CMV vaccine data, vaccine recs for upcoming climate meeting, Rift Valley fever in Senegal



News brief

Today at 3:42 p.m.
Stephanie Soucheray, MA
Topics

Rift Valley Fever

Yellow Fever

Measles

Viral Hemorrhagic Fever
  • Moderna said its cytomegalovirus (CMV) vaccine candidate, mRNA-1647, failed to meet the outcomes of preventing CMV infections in seronegative women of childbearing age in a phase 3 study. "Today's announcement is disappointing for families and healthcare professionals who have been eagerly awaiting a CMV vaccine to prevent congenital CMV, a leading infectious cause of birth defects," said Moderna CEO Stephane Bancel, MBA, MEng, in a company press release. The company will discontinue its congenital CMV clinical development program.
  • The Pan American Health Organization (PAHO) is urging attendees of the upcoming United Nations Climate Change Conference (COP30) in Brazil to get vaccinated or check their vaccination status for both measles and yellow fever. More than 60,000 expected attendees from 198 countries will travel to Belem, Para state, Brazil, for the conference , which runs from November 10 through 21. While Belem has not seen measles or yellow fever activity so far this year, high activity of both diseases in the Americas puts attendees at risk, PAHO said.
  • Rift Valley fever activity continues in Senegal, per today's weekly briefing from the Africa Centres for Disease Control and Prevention. So far there have been 277 confirmed cases and 22 deaths, for a case-fatality rate of 7.9% in this outbreak. RVF is a viral hemorrhagic fever that mainly affects livestock but can also infect people.
 
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