CID: Ebola virus persistence in breast milk after no reported illness: a likely source of virus transmission from mother to child

[tetano]

[h=1]Ebola virus persistence in breast milk after no reported illness: a likely source of virus transmission from mother to child[/h]

• Daouda Sissoko[SUP]1[/SUP],[SUP]2[/SUP],
• Mory Ke?ta[SUP]3[/SUP],
• Boubacar Diallo[SUP]3[/SUP],
• Negar Aliabadi[SUP]4[/SUP],
• David L. Fitter[SUP]4[/SUP],
• Benjamin A. Dahl[SUP]4[/SUP],
• Joseph Akoi Bore[SUP]5[/SUP],[SUP]6[/SUP],
• Fara Raymond Koundouno[SUP]5[/SUP],[SUP]6[/SUP],
• Katrin Singethan[SUP]5[/SUP],[SUP]7[/SUP],
• Sarah Meisel[SUP]5[/SUP],[SUP]8[/SUP],
• Theresa Enkirch[SUP]5[/SUP],[SUP]9[/SUP],
• Antonio Mazzarelli[SUP]5[/SUP],[SUP]10[/SUP],
• Victoria Amburgey[SUP]11[/SUP],[SUP]12[/SUP],
• Ousmane Faye[SUP]13[/SUP],
• Amadou Alpha Sall[SUP]13[/SUP],
• N?Faly Magassouba[SUP]14[/SUP],
• Miles W. Carroll[SUP]5[/SUP],[SUP]15[/SUP],[SUP]16[/SUP],
• Xavier Anglaret[SUP]1[/SUP],[SUP]17[/SUP],
• Denis Malvy[SUP]1[/SUP],[SUP]2[/SUP],
• Pierre Formenty[SUP]18[/SUP],
• Raymond Bruce Aylward[SUP]18[/SUP],
• Sakoba Ke?ta[SUP]6[/SUP],
• Mamoudou Harouna Djingarey[SUP]3[/SUP],
• Nicholas J. Loman[SUP]19[/SUP],
• Stephan G?nther[SUP]5[/SUP],[SUP]8[/SUP], and
• Sophie Duraffour[SUP]5[/SUP],[SUP]8[/SUP],*

• [SUP]1[/SUP] INSERM U1219, Bordeaux University, Bordeaux, France
• [SUP]2[/SUP] Bordeaux University Hospital, Bordeaux, France
• [SUP]3[/SUP] World Health Organization, Conakry, Guinea
• [SUP]4[/SUP] Centers for Disease Control and Prevention, Atlanta, USA
• [SUP]5[/SUP] The European Mobile Laboratory Consortium, Hamburg, Germany
• [SUP]6[/SUP] Ministry of Health Guinea, Conakry, Guinea
• [SUP]7[/SUP] Institute of Virology, Technische Universit?t M?nchen / Helmholtz Zentrum M?nchen, Munich, Germany
• [SUP]8[/SUP] Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany
• [SUP]9[/SUP] Paul-Ehrlich-Institut, Division of Veterinary Medicine, Langen, Germany
• [SUP]10[/SUP] National Institute for Infectious Diseases L. Spallanzani, Rome, Italy
• [SUP]11[/SUP] Sandia National Laboratories, Albuquerque, New Mexico, USA
• [SUP]12[/SUP] Ratoma Ebola Diagnostic Center, Conakry, Guinea.
• [SUP]13[/SUP] Institut Pasteur Dakar, Dakar, Senegal
• [SUP]14[/SUP] Universit? Gamal Abdel Nasser de Conakry, Laboratoire des Fi?vres H?morragiques en Guin?e, Conakry, Guinea
• [SUP]15[/SUP] Public Health England, Porton Down, Salisbury, UK
• [SUP]16[/SUP] University of Southampton, South General Hospital, Southampton, UK
• [SUP]17[/SUP] PAC-CI, ANRS Research Site, Treichville University Hospital, Abidjan, C?te d?Ivoire
• [SUP]18[/SUP] World Health Organization, Geneva, Switzerland
• [SUP]19[/SUP] Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK

• ↵* Corresponding author: Sophie Duraffour, Bernhard-Nocht-Institute for Tropical Medicine, Bernhard-Nocht-Str. 74, 20359 Hamburg, Germany, Phone: +49 40 42818 940, Fax: +49 40 42818 931, e-mail: sophieduraffour{at}yahoo.fr

[h=2]Abstract[/h] A nine-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother?s breast milk and the father?s seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.

full article

https://cid.oxfordjournals.org/content/early/2016/12/10/cid.ciw793.full.pdf+html