tetano
Editor, Senior Moderator
Chronic Dis Transl Med. 2020 Apr 28. doi: 10.1016/j.cdtm.2020.04.002. [Epub ahead of print]
Expert recommendations on blood purification treatment protocol for patients with severe COVID-19: Recommendation and consensus.
Yang XH[SUP]1[/SUP], Sun RH[SUP]1[/SUP], Zhao MY[SUP]2[/SUP], Chen EZ[SUP]3[/SUP], Liu J[SUP]4[/SUP], Wang HL[SUP]5[/SUP], Yang RL[SUP]6[/SUP], Chen DC[SUP]3[/SUP].
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Abstract
Coronavirus disease (COVID-19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID-19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID-19 patients have severe disease. In addition to impairment of the respiratory system, acute kidney injury (AKI) is a major complication. Immune damage mediated by cytokine storms and concomitant AKI is a key factor for poor prognosis. Based on previous experience of blood purification for patients with severe acute respiratory syndrome and Middle East respiratory syndrome combined with clinical front-line practice, we developed a blood purification protocol for patients with severe COVID-19. This protocol is divided into four major steps. The first step is to assess whether patients with severe COVID-19 require blood purification. The second step is to prescribe a blood purification treatment for patients with COVID-19. The third step is to monitor and adjust parameters of blood purification. The fourth step is to evaluate the timing of discontinuation of blood purification. It is expected that blood purification will play a key role in effectively reducing the mortality of patients with severe COVID-19 through the standardized implementation of the present protocol.
? 2020 Chinese Medical Association. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
KEYWORDS:
Blood purification treatment; COVID-19; SARS-CoV-2
PMID:32346492PMCID:PMC7186198DOI:10.1016/j.cdtm.2020.04.002
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Expert recommendations on blood purification treatment protocol for patients with severe COVID-19: Recommendation and consensus.
Yang XH[SUP]1[/SUP], Sun RH[SUP]1[/SUP], Zhao MY[SUP]2[/SUP], Chen EZ[SUP]3[/SUP], Liu J[SUP]4[/SUP], Wang HL[SUP]5[/SUP], Yang RL[SUP]6[/SUP], Chen DC[SUP]3[/SUP].
Author information
Abstract
Coronavirus disease (COVID-19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID-19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID-19 patients have severe disease. In addition to impairment of the respiratory system, acute kidney injury (AKI) is a major complication. Immune damage mediated by cytokine storms and concomitant AKI is a key factor for poor prognosis. Based on previous experience of blood purification for patients with severe acute respiratory syndrome and Middle East respiratory syndrome combined with clinical front-line practice, we developed a blood purification protocol for patients with severe COVID-19. This protocol is divided into four major steps. The first step is to assess whether patients with severe COVID-19 require blood purification. The second step is to prescribe a blood purification treatment for patients with COVID-19. The third step is to monitor and adjust parameters of blood purification. The fourth step is to evaluate the timing of discontinuation of blood purification. It is expected that blood purification will play a key role in effectively reducing the mortality of patients with severe COVID-19 through the standardized implementation of the present protocol.
? 2020 Chinese Medical Association. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.
KEYWORDS:
Blood purification treatment; COVID-19; SARS-CoV-2
PMID:32346492PMCID:PMC7186198DOI:10.1016/j.cdtm.2020.04.002
Free full text