Chinese National Influenza Center Week 48 2025

[Commonground]

Download：China flu report 2548.pdf

​Summary​

·Influenza activity in the southern and northern provinces increased. There were 1541 ILI outbreaks reported in this week.

·Among influenza viruses antigenically characterized by CNIC since March 31, 2025, 1054(98.0%) influenza A(H1N1)pdm09 viruses were characterized as A/Victoria/4897/2022-like; 415(49.9%) influenza A(H3N2) viruses were characterized as A/Croatia/10136RV/2023(egg)-like, 689(82.8%) influenza A(H3N2)viruses were characterized as A/District of Columbia/27/2023(cell)-like; 313(97.5%) influenza B/Victoria viruses were characterized as B/Austria/1359417/2021-like.

·Among the influenza viruses tested by CNIC for antiviral resistance analysis since March 31, 2025, all but 31 influenza A(H1N1)pdm09 were sensitive to neuraminidase inhibitors, all A(H3N2) and B viruses were sensitive to neuraminidase inhibitors; all A(H1N1)pdm09, A(H3N2) and B viruses were sensitive to influenza polymerase inhibitors.

Surveillance of outpatient or emergency visits for Influenza-like Illness (ILI)

During week 48, the percentage of outpatient or emergency visits for ILI (ILI%)

at national sentinel hospitals in southern provinces was 10.3%, higher than the last

week (7.8%), higher than the same week of 2022, 2023 and 2024 (3.2%, 8.7% and

3.5%). (Figure 1)


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National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention
Add: No. 155, Changbai Road, Changping District, Beijing, China(102206)
京公网安备 11011402013012号　 京ICP备11024750号​

https://ivdc.chinacdc.cn/cnic/en/Surveillance/WeeklyReport/202512/t20251203_313843.htm

 

[sharon sanders]

Please see:

China: National Influenza Center Reporting Increased Oseltamivir Resistance in Seasonal H1N1​

 

[sharon sanders]

More than 4,000 influenza-like illness outbreaks were reported nationwide in November. Has oseltamivir become resistant?

December 4, 2025, 13:46



​snip


　　According to statistics compiled by CBN reporters, from November 3, 2025 to November 30, a total of 4,351 outbreaks of influenza-like illness have been reported nationwide, of which 3,313 are related to influenza A (H3N2), accounting for approximately 76.14%.


snip


　The National Influenza Center conducted drug resistance analysis on some influenza virus strains collected since March 31, 2025. The results showed that 3.9% (31/792) of the A(H1N1)pdm09 subtype influenza virus strains showed reduced or highly reduced sensitivity to neuraminidase inhibitors, while the remaining A(H1N1)pdm09 subtype influenza virus strains were sensitive to neuraminidase inhibitors;

all A(H3N2) and type B influenza virus strains were sensitive to neuraminidase inhibitors; and all A(H1N1)pdm09, A(H3N2), and type B influenza virus strains were sensitive to polymerase inhibitors.

　　In other words, oseltamivir remains effective in treating influenza A(H3N2) subtype.

　　Yin Genquan, deputy secretary of the Party Committee and executive president of Liuzhou Hospital of Guangzhou Women and Children's Medical Center, told Yicai that the two most commonly used anti-influenza drugs in clinical practice are oseltamivir and mabaloxavir. From a clinical perspective, the drug resistance problem is not very serious, and the drug effect is still good. Of course, early medication is necessary, the earlier the better.
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