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Chinese biotech company looks to help global monkeypox drug development

Mary Wilson

Well-known member
01/06/2022

BY JIM CORNALL

Shanghai Zelixir Biotech Company Ltd. has predicted more than 600 structures and added functional annotations of proteins from monkeypox virus proteomes, which is the complete set of proteins present at a given time in the cell.

The company hopes the predicted structures will help the global quest to develop monkeypox vaccines.

... The predicted protein structures are AI-generated, and based on the complete sequence of the genome of the epidemic strain in May 2022, the whole proteome of the 2018 West African virus strain, and the whole proteome of the 1996 Congo basin virus strain.

Using its own algorithm, Zelixir said it provides annotations for all the 600+ predicted structures and managed to label the small molecules binding regions with high confidence for the 3D structure of each protein. ...

https://www.labiotech.eu/trends-news/biotech-monkeypox/
 
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