sharon sanders
Editor-in-Chief & President
Zhang Wenhong: The number of people infected in Shanghai is tens of millions, "I have been infected, and the symptoms are very mild"!
Daily Economic Newsat 08:00 on January 1, 2023
On December 30, "the demand for lung CT examination has increased sharply" appeared on the hot search. Many netizens said that there were long queues of patients waiting for CT lung examination in hospitals. 1 day or more.
A reporter from the health client of the People’s Daily called many hospitals in Beijing, Shanghai, and Guangzhou and learned that the demand for CT lung examinations in hospitals has risen sharply in the past week, and department staff are operating at full capacity. Many experts reminded that at present, most patients with new crown infection show upper respiratory tract symptoms and do not involve the lungs, so there is no need to blindly perform CT examinations.
According to the People's Daily, recently, Dr. Zhang Wenhong, the leader of the Shanghai New Crown Epidemic Prevention and Treatment Expert Group and director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, accepted an exclusive interview with Dajiangdong Studio. Zhang Wenhong said that Shanghai has reached the peak of infection since December 22. According to estimates, the current number of infections is in the tens of millions .
"In the past week, there has been no shortage of people in the CT room, especially in these two days. The number of patients waiting for registration is basically four to five hundred, which is several times higher than usual. We usually get off work at five o'clock in the afternoon, but It is now three o'clock in the afternoon, and there are more than 100 patients waiting in front of us, and there are still new registered patients, and the doctors and nurses are working overtime, and those who come late may not be able to do it." December 30, The staff of the Radiology Department of Beijing Chaoyang Integrated Traditional Chinese and Western Medicine Emergency Rescue Hospital introduced to the reporter of the People's Daily Health Client.
On December 29, Zhejiang Ningbo Radio and Television Network reported that Ningbo Beilun District Hospital of Traditional Chinese Medicine stated that the number of people who recently went to the hospital for lung CT has reached 6 times the usual number; It was announced that in order to cope with the surge in patient demand, two CTs in the hospital were running overnight, while one CT can usually meet the demand.
A number of people infected with the new crown who have undergone or successfully booked CT examinations told the People's Daily health client reporter that CT examinations are done to be prepared and for peace of mind. "I tested positive for the antigen last Friday, and it turned negative when I tested again the day before yesterday, but my cough has not stopped, especially at night, I can't sleep because of the cough. Recently, there have been a lot of discussions about 'white lung' on the Internet. I am worried. I also had inflammation in my lungs. I went to the hospital early yesterday to make an appointment and took a CT scan. The test results showed that there was a slight exudation in the lungs, which was a small infection. The doctor told me to drink more water. Let me go home ." Mr. Ma, a Beijing citizen, told the reporter of the People's Daily health client that although the final inspection result was fine, he couldn't feel relieved if he didn't do the inspection .
"In fact, the vast majority of patients with new crown infections we have seen clinically still have upper respiratory symptoms such as fever, fatigue, sore throat, nasal congestion, runny nose, etc., and do not involve lung inflammation. In fact, there is no need for CT examination." Sheng Jifang, director of the Infectious Diseases Department of the First Affiliated Hospital of Zhejiang University School of Medicine, said in an interview with a reporter from the People's Daily Health Client.
"At present, the number of patients admitted to our hospital is not small. There are only 120 patients sent by ambulances every day, and there are about 150 patients. It is true that some patients have persistent fever for many days, accompanied by dyspnea and severe cough. When there may be inflammation in the lungs, it is recommended to perform lung CT examination. Among these patients, the proportion of patients with exudative lesions (inflammation) in the lungs is not high, about 10%-20% In the meantime, although there are young people with lung involvement, it is mainly middle-aged and elderly people who have underlying diseases and have not been vaccinated." Sheng Jifang introduced.
A respiratory expert from a tertiary hospital in Beijing, who did not want to be named, told the People’s Daily health client reporter that the increase in the number of lung infections that netizens are worried about is actually caused by multiple factors. “Winter itself is a respiratory disease. In the high-incidence period, the number of patients admitted to outpatient clinics in this season in previous years will increase. Not only the new crown virus, but also many pathogens and bacteria such as respiratory syncytial virus and influenza virus will cause lung inflammation. With the increase in the number of new crown infections this year It has risen sharply, and it has affected the elderly and vulnerable groups with underlying diseases. Therefore, the absolute number of lung infections has increased significantly. However, in terms of the incidence and severity of severe pneumonia, it will definitely decrease compared to 2020 Understand."
Even if there is inflammation in the lungs, not all of them are critically ill. "There are several cases of lung effusion observed on chest X -ray. For patients with only a small amount of effusion in the lungs, we will prescribe small doses of hormones or antiviral drugs for the patient to take at home. Generally, this situation lasts for 3-5 days. It recovered . We recommend hospitalization for patients with more than 1/3 of the lung exudation area. Taking my department as an example, the average hospitalization time of patients is only about one week, and they can get better without tracheal intubation. Controllable." Sheng Jifang pointed out that the so-called 'white lung' (severe pneumonia) refers to the area of lung exudation reaching about 70%-80%. panic.
The Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology (referred to as "Wuhan Union Hospital"), located in Wuhan, Hubei Province, disclosed the hospital's recent admissions and treatment of patients with new crown infections.
According to a report from Hubei Daily on the evening of December 29, since December 7, Wuhan Union Medical College Hospital has mobilized all forces, opened up all departments of the hospital, and went all out to carry out the treatment of new coronavirus infection. A total of 16,358 patients were admitted, including severe and The number of critically ill patients was 5,414, accounting for 33.1% of the total.
"The current window is the fever clinic and emergency department, especially the emergency department." Xia Jiahong, deputy director of Wuhan Union Medical College Hospital, said that emergency patients are showing a rapid growth trend. More than 100 personnel were added to the strength of the emergency department. At the same time, all the resources of the hospital have been dredged, the boundaries of respiratory, infection, internal medicine, surgery, obstetrics and gynecology have been opened up, and critically ill patients have been treated with all their strength. It is required that each ward must have the function and conditions of tracheal intubation, and do everything possible to rescue critically ill patients. After the ward is remodeled, the number of critically ill patients should reach 8%.
According to reports, after this period of operation, the hospital has maintained a good operating situation. As of press time, Wuhan Union Medical College Hospital admits 1,500 to 1,800 patients every day, and 500 to 800 patients are discharged. The total number of patients in the hospital is about 7,400, of which new crown infections account for about 40%.
According to the "Changjiang Daily" report, Wuhan Union Medical College Hospital has also become the medical institution that has treated the most critically ill patients with new crown infection in Hubei Province since December 7.
According to hospital statistics, the success rate of critically ill patients is about 97%, and the prognosis is good .
According to CCTV's "News 1+1", Kang Yan, professor of critical care medicine at West China Hospital of Sichuan University and president of West China Tianfu Hospital, said that West China Tianfu Hospital of Sichuan University currently has 800 beds open . The number of patients going to fever clinics and emergency departments has increased significantly .
In the last week or so, we had nearly 450 emergency and fever clinic visits every day, and about 10% of them, 40 to 50, had some changes in lung inflammation and required hospitalization . Among the nearly 2,500 patients who visited the doctor this week, we probably received more than 50 patients (about 2%) in the ICU .
Generally speaking, the severe characteristics of these patients are still very typical. First of all, they are elderly and have underlying diseases. The average age of our inpatients is 69.7 years old, and the average age of ICU patients is 69.9 years old, and the elderly are all 92 to 98 years old. Aged, and often accompanied by underlying diseases, including high blood pressure, diabetes, or chronic renal insufficiency and so on. In addition to the conventional symptoms of new crown infection, their main symptoms are often accompanied by acute hypoxia, so this is basically the same as the overall performance and clinical features of the severe new crown patients we have seen before.
According to the People's Daily, recently, Dr. Zhang Wenhong, the leader of the Shanghai New Crown Epidemic Prevention and Treatment Expert Group and director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, accepted an exclusive interview with Dajiangdong Studio.
Zhang Wenhong said that Shanghai has reached the peak of infection since December 22. According to estimates, the current number of infections is in the tens of millions . Assuming that 0.5% of the 10 million infected people in Shanghai need to be hospitalized, it means that 50,000 people will need to be hospitalized in the next few weeks. All major hospitals will admit thousands of people without exception, and those who are particularly critical will need respiratory support. Therefore, although the proportion of severe cases among the infected population is low, the base number is large, and the absolute number of people is still large . This is the characteristic of this wave of Omicron infection—we are facing the severe situation that all countries have experienced at the beginning of the epidemic. challenge.
Zhang Wenhong emphasized that this time, it is a full-scale power showdown between us and Omicron . There is no opportunity to make things happen. It is not that the tertiary hospitals can open a few more intensive care units to solve the problem of treatment. It is necessary to mobilize effectively from the grassroots to the center. Every family must also know how to protect the vulnerable population and under what circumstances to go to the hospital for treatment; Every community health center can also expand the treatment force as much as possible... Struggling to hold on to the threshold of infection of vulnerable groups, we can grit our teeth and pass through this pandemic.
He said that the current main virus strains are all widely circulated abroad, and some scholars have done virulence comparisons. The severe disease rate and mortality rate of BA.5 and BF.7 are very close to those of the first generation Omicron . After infection, many people feel severe symptoms such as fever and muscle aches, and they have given fancy names, such as "blade strain" and "dry rice strain", but such people are still mild . Severe cases are clearly defined in medicine: dyspnea, oxygen saturation below 93%; CT scans show extensive infiltration of the lungs, large shadows or even white lungs. If oxygen inhalation is useless, and tracheotomy and mechanical ventilation are required, it is a critical illness. We have carried out continuous monitoring of the virus genome, and no new special strains have been found so far. Shanghai is currently mainly BA.5 and BF.7, and the proportion of them causing severe illness is clear.
Zhang Wenhong said that he had also been infected with Omicron . " My symptoms were very mild . On the first day, I rested at home and held six or seven online meetings; on the second day, I went to the positive ward for rounds. No one around thought I had been infected, because I was in the ward every day, Work. I had my fourth shot and my own experience has made me more supportive of vaccinations," he said.
He emphasized that nutrition is the basis for the treatment of new crown infection. Nourishment leads to resistance[/COLOR] . The importance of nutrition cannot be overemphasized. I hope that during this period of time, all infected people or elderly people who are observing at home must pay special attention to increasing nutrition, including a diverse and balanced intake of vegetables, carbohydrates, etc., and the intake of high-quality protein is the most important thing.[/COLOR]
When the reporter asked, at the beginning of 2022, you said that you studied the medical images of Omicron-infected people, not the "big flu", and thought that this mutant strain "will bite people". What did you see on the image? Now look, where does it mainly "bite"?
Zhang Wenhong said that at that time, many people believed that Omicron only invaded the upper respiratory tract, and its virulence decreased. Compared with the Delta strain, the virulence of Omicron was indeed significantly reduced. At the beginning of 2022, Shanghai will assume the function of the main entry point for international flights, and imported cases will continue. I watched the film and saw that the overall incidence of severe cases of Omicron is decreasing, but there are still pneumonia manifestations in vulnerable groups. The actual clinical situation tells us that it cannot be said that Omicron will not affect everyone. Dangerous , will not invade the lungs.
Influenza has been circulating in the world for more than 100 years, and we have also established a certain degree of cross immunity. The new crown is a new virus, and if the infection spreads widely, the risk will be magnified rapidly. More recently, we've been able to see more clearly that Omicron does "bite,"with vulnerable populations developing symptoms of pneumonia, and some even requ
We are now in the stage of the first wave of impact of Omicron, which is particularly rapid after the opening, and it is particularly difficult. It is necessary to gather the strength of the whole society, expand medical resources, protect vulnerable groups, and strive to withstand the impact of Omicron, get out of this wave of epidemics, and win the final victory.
According to Jiemian News, recently, on social media, citizens in many places are asking for intravenous human immunoglobulin .
Among the drug buyers, most of them express the situation as: their family members are hospitalized, their condition is relatively critical, and they need this drug. In the help text, there are many words such as "critically ill", "severe illness", "life-saving medicine" and "lung infection". In terms of territories, it has occurred in Hubei, Sichuan, Hebei, Shaanxi, Jilin and other places.
In addition, on social media, remarks such as "relying on this to continue life after being positive" and "improving immunity is a good thing" have also appeared regarding the intravenous injection of human immunoglobulin.
In fact, intravenous human immunoglobulin (PH4) is not a new product. It is also called "static C", "globulin" and "globulin". It belongs to blood products and is an immunoglobulin extracted from the plasma of healthy people. The "intravenous" in its name means intravenous injection. Generally speaking, the most common usage scenario of intravenous human immunoglobulin is to neutralize pathogens (microbes that can cause diseases in the human body, such as viruses, bacteria, etc.) when various severe infections occur, and achieve anti-infection effects.
At present, intravenous human immunoglobulin is mainly used in hospitals for patients with severe new crown infection, which has no preventive effect, and it is not necessary for ordinary infected patients
On December 30, a pharmacist at a tertiary hospital in Shanghai explained in an interview with a reporter from Jiemian News, “It’s not that the word “immune” in the drug can improve immunity. Ordinary people and patients with mild symptoms don’t need to use it . Preventing infection cannot prevent severe illness .” He reminded that such products are medicines that are usually in short supply in hospitals . people in need.
The aforementioned person said that one of the indications for intravenous human immunoglobulin is severe infection, and it is more often used in ICU wards. The so-called "severe infection" is common in infections caused by various bacteria and fungi, or mixed infections. In bacterial infection, because there will be various drug-resistant bacteria in the bacteria, which will make the antibiotics ineffective, which will cause the patient's extremely serious infection and life-threatening clinical manifestations, so the doctor will decide to use human immunoglobulin. In terms of patient groups, cancer patients who develop into late stages are prone to severe infections and will use this product. And, patients with idiopathic thrombocytopenic purpura or Kawasaki disease in Children's Hospital will also use this product.
He believes that in the current treatment of new crowns, it is expected that patients with pneumonia combined with basic diseases, chronic diseases or other diseases, especially elderly patients, will be prone to severe infections caused by other bacterial infections once their diseases worsen and become severe. Under such circumstances, intravenous injection of human immunoglobulin can be tried, but for ordinary people and new crowns, "it will not be used at all, and patients with light and ordinary new crowns do not need to use it."
In fact, as early as the beginning of 2020, intravenous injection of human immunoglobulin has been used as a treatment for severe patients with new crowns. In March 2020, Li Taisheng, an infection physician at Peking Union Medical College Hospital, said in an interview with Health Daily that improving the immune function of patients and reducing the storm of inflammatory factors are two key links in the treatment of severe patients with new crowns. Treatment options with immunoglobulin combined with other drugs.
According to Li Taisheng, the recommended dose of intravenous human immunoglobulin is 0.3-0.5g/(kg.d), and the course of treatment is about 5 days. Effectively reduce the fatality rate of critically ill patients.
In addition, since the half-life of immunoglobulin in the human body (the time it takes for the drug's blood concentration to decrease by half) is only about 2 weeks, multiple injections of low doses are usually required depending on the disease state. Based on the unit price of this product is generally in the range of 500 to 600 yuan per piece, the overall use price is not cheap. In terms of transportation, this product is different from medicines that can be stored at normal room temperature, and its transportation must meet low temperature conditions.
According to the section "Antiviral Therapy" in the "Diagnosis and Treatment Program for Novel Coronavirus Pneumonia (Trial Ninth Edition)", it can be used in patients with high-risk factors, high viral load, and rapid disease progression early in the course of the disease. Inject the new crown-specific immunoglobulin (COVID-19 human immunoglobulin), the dosage is 100mg/kg for light type, 200mg/kg for common type, and 400mg/kg for heavy type; according to the improvement of the patient's condition, it can be infused again the next day. No more than 5 times.
zhttps://news.sina.com.cn/s/2023-01-01/doc-imxyrtrq9144713.shtml?cre=tianyi&mod=pcpager_china &loc=35&r=0&rfunc=89&tj=cxvertical_pc_pager_spt &tr =181#/
Daily Economic Newsat 08:00 on January 1, 2023
On December 30, "the demand for lung CT examination has increased sharply" appeared on the hot search. Many netizens said that there were long queues of patients waiting for CT lung examination in hospitals. 1 day or more.
A reporter from the health client of the People’s Daily called many hospitals in Beijing, Shanghai, and Guangzhou and learned that the demand for CT lung examinations in hospitals has risen sharply in the past week, and department staff are operating at full capacity. Many experts reminded that at present, most patients with new crown infection show upper respiratory tract symptoms and do not involve the lungs, so there is no need to blindly perform CT examinations.
According to the People's Daily, recently, Dr. Zhang Wenhong, the leader of the Shanghai New Crown Epidemic Prevention and Treatment Expert Group and director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, accepted an exclusive interview with Dajiangdong Studio. Zhang Wenhong said that Shanghai has reached the peak of infection since December 22. According to estimates, the current number of infections is in the tens of millions .
The hospital is full of CT appointments
Citizens: Don’t worry if you don’t check
"In the past week, there has been no shortage of people in the CT room, especially in these two days. The number of patients waiting for registration is basically four to five hundred, which is several times higher than usual. We usually get off work at five o'clock in the afternoon, but It is now three o'clock in the afternoon, and there are more than 100 patients waiting in front of us, and there are still new registered patients, and the doctors and nurses are working overtime, and those who come late may not be able to do it." December 30, The staff of the Radiology Department of Beijing Chaoyang Integrated Traditional Chinese and Western Medicine Emergency Rescue Hospital introduced to the reporter of the People's Daily Health Client.
On December 29, Zhejiang Ningbo Radio and Television Network reported that Ningbo Beilun District Hospital of Traditional Chinese Medicine stated that the number of people who recently went to the hospital for lung CT has reached 6 times the usual number; It was announced that in order to cope with the surge in patient demand, two CTs in the hospital were running overnight, while one CT can usually meet the demand.
A number of people infected with the new crown who have undergone or successfully booked CT examinations told the People's Daily health client reporter that CT examinations are done to be prepared and for peace of mind. "I tested positive for the antigen last Friday, and it turned negative when I tested again the day before yesterday, but my cough has not stopped, especially at night, I can't sleep because of the cough. Recently, there have been a lot of discussions about 'white lung' on the Internet. I am worried. I also had inflammation in my lungs. I went to the hospital early yesterday to make an appointment and took a CT scan. The test results showed that there was a slight exudation in the lungs, which was a small infection. The doctor told me to drink more water. Let me go home ." Mr. Ma, a Beijing citizen, told the reporter of the People's Daily health client that although the final inspection result was fine, he couldn't feel relieved if he didn't do the inspection .
"In fact, the vast majority of patients with new crown infections we have seen clinically still have upper respiratory symptoms such as fever, fatigue, sore throat, nasal congestion, runny nose, etc., and do not involve lung inflammation. In fact, there is no need for CT examination." Sheng Jifang, director of the Infectious Diseases Department of the First Affiliated Hospital of Zhejiang University School of Medicine, said in an interview with a reporter from the People's Daily Health Client.
"At present, the number of patients admitted to our hospital is not small. There are only 120 patients sent by ambulances every day, and there are about 150 patients. It is true that some patients have persistent fever for many days, accompanied by dyspnea and severe cough. When there may be inflammation in the lungs, it is recommended to perform lung CT examination. Among these patients, the proportion of patients with exudative lesions (inflammation) in the lungs is not high, about 10%-20% In the meantime, although there are young people with lung involvement, it is mainly middle-aged and elderly people who have underlying diseases and have not been vaccinated." Sheng Jifang introduced.
A respiratory expert from a tertiary hospital in Beijing, who did not want to be named, told the People’s Daily health client reporter that the increase in the number of lung infections that netizens are worried about is actually caused by multiple factors. “Winter itself is a respiratory disease. In the high-incidence period, the number of patients admitted to outpatient clinics in this season in previous years will increase. Not only the new crown virus, but also many pathogens and bacteria such as respiratory syncytial virus and influenza virus will cause lung inflammation. With the increase in the number of new crown infections this year It has risen sharply, and it has affected the elderly and vulnerable groups with underlying diseases. Therefore, the absolute number of lung infections has increased significantly. However, in terms of the incidence and severity of severe pneumonia, it will definitely decrease compared to 2020 Understand."
Even if there is inflammation in the lungs, not all of them are critically ill. "There are several cases of lung effusion observed on chest X -ray. For patients with only a small amount of effusion in the lungs, we will prescribe small doses of hormones or antiviral drugs for the patient to take at home. Generally, this situation lasts for 3-5 days. It recovered . We recommend hospitalization for patients with more than 1/3 of the lung exudation area. Taking my department as an example, the average hospitalization time of patients is only about one week, and they can get better without tracheal intubation. Controllable." Sheng Jifang pointed out that the so-called 'white lung' (severe pneumonia) refers to the area of lung exudation reaching about 70%-80%. panic.
Wuhan Xiehe: 33% of patients admitted to the hospital are critically ill
Sichuan Huaxi: ICU patients account for about 2%
The Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology (referred to as "Wuhan Union Hospital"), located in Wuhan, Hubei Province, disclosed the hospital's recent admissions and treatment of patients with new crown infections.
According to a report from Hubei Daily on the evening of December 29, since December 7, Wuhan Union Medical College Hospital has mobilized all forces, opened up all departments of the hospital, and went all out to carry out the treatment of new coronavirus infection. A total of 16,358 patients were admitted, including severe and The number of critically ill patients was 5,414, accounting for 33.1% of the total.
"The current window is the fever clinic and emergency department, especially the emergency department." Xia Jiahong, deputy director of Wuhan Union Medical College Hospital, said that emergency patients are showing a rapid growth trend. More than 100 personnel were added to the strength of the emergency department. At the same time, all the resources of the hospital have been dredged, the boundaries of respiratory, infection, internal medicine, surgery, obstetrics and gynecology have been opened up, and critically ill patients have been treated with all their strength. It is required that each ward must have the function and conditions of tracheal intubation, and do everything possible to rescue critically ill patients. After the ward is remodeled, the number of critically ill patients should reach 8%.
According to reports, after this period of operation, the hospital has maintained a good operating situation. As of press time, Wuhan Union Medical College Hospital admits 1,500 to 1,800 patients every day, and 500 to 800 patients are discharged. The total number of patients in the hospital is about 7,400, of which new crown infections account for about 40%.
According to the "Changjiang Daily" report, Wuhan Union Medical College Hospital has also become the medical institution that has treated the most critically ill patients with new crown infection in Hubei Province since December 7.
According to hospital statistics, the success rate of critically ill patients is about 97%, and the prognosis is good .
According to CCTV's "News 1+1", Kang Yan, professor of critical care medicine at West China Hospital of Sichuan University and president of West China Tianfu Hospital, said that West China Tianfu Hospital of Sichuan University currently has 800 beds open . The number of patients going to fever clinics and emergency departments has increased significantly .
In the last week or so, we had nearly 450 emergency and fever clinic visits every day, and about 10% of them, 40 to 50, had some changes in lung inflammation and required hospitalization . Among the nearly 2,500 patients who visited the doctor this week, we probably received more than 50 patients (about 2%) in the ICU .
Generally speaking, the severe characteristics of these patients are still very typical. First of all, they are elderly and have underlying diseases. The average age of our inpatients is 69.7 years old, and the average age of ICU patients is 69.9 years old, and the elderly are all 92 to 98 years old. Aged, and often accompanied by underlying diseases, including high blood pressure, diabetes, or chronic renal insufficiency and so on. In addition to the conventional symptoms of new crown infection, their main symptoms are often accompanied by acute hypoxia, so this is basically the same as the overall performance and clinical features of the severe new crown patients we have seen before.
Zhang Wenhong: Shanghai has reached its peak
The number of infected people is in the tens of millions
According to the People's Daily, recently, Dr. Zhang Wenhong, the leader of the Shanghai New Crown Epidemic Prevention and Treatment Expert Group and director of the Department of Infectious Diseases at Huashan Hospital affiliated to Fudan University, accepted an exclusive interview with Dajiangdong Studio.
Zhang Wenhong said that Shanghai has reached the peak of infection since December 22. According to estimates, the current number of infections is in the tens of millions . Assuming that 0.5% of the 10 million infected people in Shanghai need to be hospitalized, it means that 50,000 people will need to be hospitalized in the next few weeks. All major hospitals will admit thousands of people without exception, and those who are particularly critical will need respiratory support. Therefore, although the proportion of severe cases among the infected population is low, the base number is large, and the absolute number of people is still large . This is the characteristic of this wave of Omicron infection—we are facing the severe situation that all countries have experienced at the beginning of the epidemic. challenge.
Zhang Wenhong emphasized that this time, it is a full-scale power showdown between us and Omicron . There is no opportunity to make things happen. It is not that the tertiary hospitals can open a few more intensive care units to solve the problem of treatment. It is necessary to mobilize effectively from the grassroots to the center. Every family must also know how to protect the vulnerable population and under what circumstances to go to the hospital for treatment; Every community health center can also expand the treatment force as much as possible... Struggling to hold on to the threshold of infection of vulnerable groups, we can grit our teeth and pass through this pandemic.
He said that the current main virus strains are all widely circulated abroad, and some scholars have done virulence comparisons. The severe disease rate and mortality rate of BA.5 and BF.7 are very close to those of the first generation Omicron . After infection, many people feel severe symptoms such as fever and muscle aches, and they have given fancy names, such as "blade strain" and "dry rice strain", but such people are still mild . Severe cases are clearly defined in medicine: dyspnea, oxygen saturation below 93%; CT scans show extensive infiltration of the lungs, large shadows or even white lungs. If oxygen inhalation is useless, and tracheotomy and mechanical ventilation are required, it is a critical illness. We have carried out continuous monitoring of the virus genome, and no new special strains have been found so far. Shanghai is currently mainly BA.5 and BF.7, and the proportion of them causing severe illness is clear.
Zhang Wenhong said that he had also been infected with Omicron . " My symptoms were very mild . On the first day, I rested at home and held six or seven online meetings; on the second day, I went to the positive ward for rounds. No one around thought I had been infected, because I was in the ward every day, Work. I had my fourth shot and my own experience has made me more supportive of vaccinations," he said.
He emphasized that nutrition is the basis for the treatment of new crown infection. Nourishment leads to resistance[/COLOR] . The importance of nutrition cannot be overemphasized. I hope that during this period of time, all infected people or elderly people who are observing at home must pay special attention to increasing nutrition, including a diverse and balanced intake of vegetables, carbohydrates, etc., and the intake of high-quality protein is the most important thing.[/COLOR]
When the reporter asked, at the beginning of 2022, you said that you studied the medical images of Omicron-infected people, not the "big flu", and thought that this mutant strain "will bite people". What did you see on the image? Now look, where does it mainly "bite"?
Zhang Wenhong said that at that time, many people believed that Omicron only invaded the upper respiratory tract, and its virulence decreased. Compared with the Delta strain, the virulence of Omicron was indeed significantly reduced. At the beginning of 2022, Shanghai will assume the function of the main entry point for international flights, and imported cases will continue. I watched the film and saw that the overall incidence of severe cases of Omicron is decreasing, but there are still pneumonia manifestations in vulnerable groups. The actual clinical situation tells us that it cannot be said that Omicron will not affect everyone. Dangerous , will not invade the lungs.
Influenza has been circulating in the world for more than 100 years, and we have also established a certain degree of cross immunity. The new crown is a new virus, and if the infection spreads widely, the risk will be magnified rapidly. More recently, we've been able to see more clearly that Omicron does "bite,"with vulnerable populations developing symptoms of pneumonia, and some even requ
We are now in the stage of the first wave of impact of Omicron, which is particularly rapid after the opening, and it is particularly difficult. It is necessary to gather the strength of the whole society, expand medical resources, protect vulnerable groups, and strive to withstand the impact of Omicron, get out of this wave of epidemics, and win the final victory.
Many places rush to buy intravenous human immunoglobulin
Experts:
neither prevent infection nor severe illness
According to Jiemian News, recently, on social media, citizens in many places are asking for intravenous human immunoglobulin .
Among the drug buyers, most of them express the situation as: their family members are hospitalized, their condition is relatively critical, and they need this drug. In the help text, there are many words such as "critically ill", "severe illness", "life-saving medicine" and "lung infection". In terms of territories, it has occurred in Hubei, Sichuan, Hebei, Shaanxi, Jilin and other places.
In addition, on social media, remarks such as "relying on this to continue life after being positive" and "improving immunity is a good thing" have also appeared regarding the intravenous injection of human immunoglobulin.
In fact, intravenous human immunoglobulin (PH4) is not a new product. It is also called "static C", "globulin" and "globulin". It belongs to blood products and is an immunoglobulin extracted from the plasma of healthy people. The "intravenous" in its name means intravenous injection. Generally speaking, the most common usage scenario of intravenous human immunoglobulin is to neutralize pathogens (microbes that can cause diseases in the human body, such as viruses, bacteria, etc.) when various severe infections occur, and achieve anti-infection effects.
At present, intravenous human immunoglobulin is mainly used in hospitals for patients with severe new crown infection, which has no preventive effect, and it is not necessary for ordinary infected patients
On December 30, a pharmacist at a tertiary hospital in Shanghai explained in an interview with a reporter from Jiemian News, “It’s not that the word “immune” in the drug can improve immunity. Ordinary people and patients with mild symptoms don’t need to use it . Preventing infection cannot prevent severe illness .” He reminded that such products are medicines that are usually in short supply in hospitals . people in need.
The aforementioned person said that one of the indications for intravenous human immunoglobulin is severe infection, and it is more often used in ICU wards. The so-called "severe infection" is common in infections caused by various bacteria and fungi, or mixed infections. In bacterial infection, because there will be various drug-resistant bacteria in the bacteria, which will make the antibiotics ineffective, which will cause the patient's extremely serious infection and life-threatening clinical manifestations, so the doctor will decide to use human immunoglobulin. In terms of patient groups, cancer patients who develop into late stages are prone to severe infections and will use this product. And, patients with idiopathic thrombocytopenic purpura or Kawasaki disease in Children's Hospital will also use this product.
He believes that in the current treatment of new crowns, it is expected that patients with pneumonia combined with basic diseases, chronic diseases or other diseases, especially elderly patients, will be prone to severe infections caused by other bacterial infections once their diseases worsen and become severe. Under such circumstances, intravenous injection of human immunoglobulin can be tried, but for ordinary people and new crowns, "it will not be used at all, and patients with light and ordinary new crowns do not need to use it."
In fact, as early as the beginning of 2020, intravenous injection of human immunoglobulin has been used as a treatment for severe patients with new crowns. In March 2020, Li Taisheng, an infection physician at Peking Union Medical College Hospital, said in an interview with Health Daily that improving the immune function of patients and reducing the storm of inflammatory factors are two key links in the treatment of severe patients with new crowns. Treatment options with immunoglobulin combined with other drugs.
According to Li Taisheng, the recommended dose of intravenous human immunoglobulin is 0.3-0.5g/(kg.d), and the course of treatment is about 5 days. Effectively reduce the fatality rate of critically ill patients.
In addition, since the half-life of immunoglobulin in the human body (the time it takes for the drug's blood concentration to decrease by half) is only about 2 weeks, multiple injections of low doses are usually required depending on the disease state. Based on the unit price of this product is generally in the range of 500 to 600 yuan per piece, the overall use price is not cheap. In terms of transportation, this product is different from medicines that can be stored at normal room temperature, and its transportation must meet low temperature conditions.
According to the section "Antiviral Therapy" in the "Diagnosis and Treatment Program for Novel Coronavirus Pneumonia (Trial Ninth Edition)", it can be used in patients with high-risk factors, high viral load, and rapid disease progression early in the course of the disease. Inject the new crown-specific immunoglobulin (COVID-19 human immunoglobulin), the dosage is 100mg/kg for light type, 200mg/kg for common type, and 400mg/kg for heavy type; according to the improvement of the patient's condition, it can be infused again the next day. No more than 5 times.
zhttps://news.sina.com.cn/s/2023-01-01/doc-imxyrtrq9144713.shtml?cre=tianyi&mod=pcpager_china &loc=35&r=0&rfunc=89&tj=cxvertical_pc_pager_spt &tr =181#/