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China - The number of children with respiratory syncytial virus has increased in many places including, Henan, Hunan, Sichuan provinces - April 27, 20

sharon sanders

Editor-in-Chief & President
The number of children with respiratory syncytial virus infection has increased in many places, and there is currently no antiviral drug

2023-04-27 14:08BeijingPeople's Daily Health Client
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( People's Daily Health Client Reporter Liu Jingyi ) Recently, hospitals in Zhoukou City, Henan Province, Maternal and Child Health Hospital, Sansanyi Hospital, Zhuzhou City, Hunan Province and many other hospitals issued documents stating that the recent high incidence of respiratory syncytial virus in hospitals, and the number of children with respiratory syncytial virus infection admitted to the hospital rise.
The "Technical Guidelines for Clinical Trials of Respiratory Syncytial Virus Infection Drugs" issued by the Center for Drug Evaluation of the State Food and Drug Administration pointed out that at present, there is no RSV vaccine and proven effective antiviral drugs for the treatment of RSV . Lin Xiaoliang, deputy chief physician of the Respiratory Department of Xiamen Hospital (Xiamen Children's Hospital), Children's Hospital Affiliated to Fudan University, told the People's Daily Health client reporter that this is mainly due to insufficient research on the structural characteristics of RSV and the mechanism of RSV infection and immunity Thoroughly related.
Multi-site syncytial virus infection on the rise
The Zhoukou City Maternal and Child Health Hospital issued a document on April 21 stating, "The number of children in our hospital's pediatric outpatient clinic and ward is increasing day by day, mainly children with fever, cough, runny nose, and wheezing. The number of daily visits can reach 500-600. After inspection, it was found that most of them were caused by syncytial virus infection, and a few could be combined with rhinovirus."
Sichuan Online reported on April 24 that the number of children infected with respiratory syncytial virus in Sichuan Province has also increased recently. Pang Ying, chief physician of the Pediatric Respiratory Medicine Department of Sichuan Maternal and Child Health Hospital, said, "Now 80% of the children with pneumonia in our inpatient department are It is caused by respiratory syncytial virus infection. In the outpatient clinic, I see nearly a hundred children every day, and about 20% of the children are infected with the virus."
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Lin Xiaoliang, deputy chief physician of the Respiratory Department of Xiamen Hospital (Xiamen Children's Hospital), Children's Hospital Affiliated to Fudan University, told the People's Daily Health client reporter that respiratory syncytial virus is a single-stranded RNA virus, which usually enters the body of susceptible children through air droplets or direct contact. Respiratory tract, which first proliferates in the mucosa of the nasopharynx, usually causing upper respiratory tract infection. "Infection is more common in infants and young children, and more than half of them are infants under 1 year old. The incubation period after infection is about 4-5 days. In the early stage, symptoms of upper respiratory tract infection such as cough, nasal congestion, and runny nose may appear; it may be accompanied by fever; if Respiratory syncytial virus infection involves the lower respiratory tract, and severe coughing, wheezing, and even wheezing, shortness of breath and other symptoms may occur; in severe cases, respiratory failure such as hypoxia and cyanosis may occur."
Infants under the age of 2 are susceptible
According to the "Technical Guidelines for Clinical Trials of Respiratory Syncytial Virus Infection Drugs" issued by the Drug Evaluation Center of the State Food and Drug Administration, respiratory syncytial virus is the most common viral pathogen that causes acute lower respiratory tract infections in children under 5 years of age worldwide Leading cause of hospitalization for viral respiratory infection in young children. The data show that acute lower respiratory tract infection in children caused by respiratory syncytial virus infection accounts for 28% of all acute lower respiratory tract infections in children, among which children who die in hospital due to respiratory syncytial virus account for 13%-22% of the deaths caused by acute lower respiratory tract infection in children .
The guiding principle points out that the respiratory syncytial virus epidemic season in northern China usually starts from mid-October to mid-May of the following year, and it occurs more frequently in winter and spring in southern China, which is closely related to temperature and may last up to 8 months. Respiratory syncytial virus has only one serotype, which is divided into two subtypes, A and B, and there is an alternating epidemic trend in northern my country.
"Respiratory syncytial virus infection is distributed throughout the year, and its high-incidence season varies with regions and climates. Its prevalence is mainly affected by comprehensive factors such as geographical location, temperature, humidity, and population density." Lin Xiaoliang accepted People's Daily Health The client reporter said in an interview.
" An effective preventive measure for respiratory syncytial virus infection is to protect the susceptible population. This disease occurs in infants under 2 years old, mainly related to the immature immune system of infants and young children. During the virus epidemic season, infants and young children need to strengthen protection and avoid Infection: Pay attention to changing clothes according to the weather, avoid getting cold and overheating, and avoid excessive excitement or fatigue. These may lead to a decrease in the child's resistance; at the same time, avoid going to crowded places and try to avoid contact with respiratory infections. If a child develops symptoms such as fever, cough, and wheezing, they should be sent to the doctor in time." Lin Xiaoliang reminded.


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