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China - New H7N9 Cases Confirmed and Suspected for April 4, 2013 - 3 new cases (total=14), 2 new deaths (total=6)

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Re: China - 14 confirmed cases of human infection with H7N9 avian influenza - Five fatalities March 31 +

Re: China - 14 confirmed cases of human infection with H7N9 avian influenza - Five fatalities March 31 +

Source: http://big5.xinhuanet.com/gate/big5/news.xinhuanet.com/english/china/2013-04/04/c_132285178.htm


China reports 5th death from H7N9 bird flu
English.news.cn 2013-04-04 23:00:20

SHANGHAI, April 4 (Xinhua) -- Authorities in Shanghai said Thursday night that another person has died from H7N9 bird flu, bringing the death toll from the new deadly strain to five around the country.

The city has reported six infections to date, and four have died, said the Shanghai Municipal Health and Family Planning Commission.

Of the rest two, there was a four-year-old, the agency said. The baby was recovering from mild illness, it added.

The person died at Huashan Hospital on Wednesday and was confirmed infected with the H7N9 strain on Thursday. The commission gave no further information on the latest case.

Also on Thursday, the commission reported the city's third death from the H7N9 bird flu.

The case involved a 48-year-old man surnamed Chu, a poultry transporter from Rugao in neighboring Jiangsu Province.

He developed symptoms of cough on March 28. After having a fever on Monday, he went to a private clinic for treatment. The man then sought help in the Tongji Hospital in Shanghai in the early hours of Wednesday after his condition worsened.

Chu died three hours after being admitted to the hospital. He was confirmed infected with the H7N9 virus on Thursday. Eight people who had close contact with him have shown no abnormal symptoms.

So far, China has confirmed 14 H7N9 cases -- six in Shanghai, four in Jiangsu, three in Zhejiang and one in Anhui, in the first known human infections of the lesser-known strain. Of all, four died in Shanghai and one died in Zhejiang...
 
Re: H7N9, Shanghai: New case of human infection; 11 cases overall in China (Ifeng/CCTV, April 4 2013)

Re: H7N9, Shanghai: New case of human infection; 11 cases overall in China (Ifeng/CCTV, April 4 2013)

[Source: Centre for Health Protection, Hong Kong PRC SAR, full text: (LINK).]

Notification of three more human cases of H7N9 in Shanghai


The Centre for Health Protection (CHP) of the Department of Health received notification from the National Health and Family Planning Commission (the Commission) tonight (April 4) concerning three more confirmed human cases of influenza A (H7N9).

A CHP spokesman said the three cases involved a 67-year-old woman, who is in critical condition; a 4-year-old boy, who is in satisfactory condition; and a 52-year-old female patient who passed away yesterday (April 3).

Laboratory tests on the three patients' specimens by the Mainland health authorities yielded a positive result for H7N9.

According to the Commission, no epidemiological link between the three cases was identified.

So far, except a close contact of the 52-year-old female patient developed fever and runny nose, no abnormality was detected among the other 51 close contacts of three cases.

The spokesman said that influenza A (H7) is a statutorily notifiable infectious disease in Hong Kong. The CHP is maintaining close liaison with the Mainland health authorities to obtain more information on the cases.

"We will heighten our vigilance and continue to maintain stringent port health measures in connection with this development," the spokesman said.

The spokesman also advised travellers especially those returning from Shanghai, Anhui, Jiangsu and Zhejiang with respiratory symptoms to wear facial masks and seek medical attention and reveal their travel histories to doctors. Health-care professionals should also pay special attention to those travellers who might have contact with birds or poultry in the four places.

The spokesman reminded members of the public to remain vigilant against avian influenza infection and to observe the following measures:
  • Avoid direct contact with poultry and birds or their droppings; if contacts have been made, they should wash hands thoroughly with soap and water;
  • Poultry and eggs should be thoroughly cooked before eating;
  • Wash hands frequently;
  • Cover nose and mouth while sneezing or coughing, hold the spit with tissue and put it into covered dustbins;
  • Avoid crowded places and contact with sick people with fever;
  • Wear a mask when you have respiratory symptoms or need to take care of patients with fever; and
  • When you have fever and influenza-like illnesses during a trip or when coming back to Hong Kong, you should consult doctors promptly and reveal your travel history.
For further information on avian influenza, please visit the CHP's website (www.chp.gov.hk).


Ends/Thursday, April 4, 2013
Issued at HKT 23:51
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China - New H7N9 Cases Confirmed and Suspected for April 4, 2013

China - New H7N9 Cases Confirmed and Suspected for April 4, 2013

Xinhua, Shanghai, April 4 (Xinhua Chou Yi Li Rong) reporter learned from the Shanghai Municipal Health and Family Planning Commission, ended at 11 p.m. on the 4th Shanghai were found in six cases of human infection with the H7N9avian influenza confirmed cases, 4 deaths, 2 cases are where the six cases had no relevance. Close contacts of a death case, a fever, runny nose, itchy throat, and other symptoms, has been treated in isolation.

Patients with certain she died on April 3, 4 pm, Shanghai Municipal Center for Disease Control and Prevention report laboratory test results for the H7N9 avian influenza virus nucleic acid positive. After investigation, a total of 31 close contacts of the case, so far, a fever, runny nose, itchy throat and other symptoms, at 18:53 on the 4th isolation and treatment have been transferred to the Shanghai Public Health Clinical Center, the other close contact were not found to have a fever or respiratory symptoms.

The date of the National Avian Influenza Reference Laboratory from ShanghaiMunicipal censorship, Songjiang District, Shanghai Huai agricultural and sideline products wholesale markets dove samples detected the H7N9 avian influenza virus. Shanghai Municipal Agricultural Commission has been the day of the urgent deployment of avian flu prevention and control measures, immediately turn off the live poultry trading of agricultural and sideline products wholesale market in Shanghai Huai, culling the trading of all birds in the region.

According to the Shanghai Municipal Agricultural Commission said the emergency notification requirements in accordance with the General Office of the Ministry of Agriculture to prevent and control the spread of the H7N9 avian flu virus has animal infected with the H7N9 bird flu virus as an animal disease management, immediately start contingency plans. Shanghai will pause this time the detected H7 avian influenza virus Minhang Jingchuang grocer, Feng Chuang market trading of live poultry, and do a good job of on-site:tiphat:http://news.xinhuanet.com/2013-04/05/c_124541805.htm
 
Re: A close contact with H7N9 infected with the fever and other symptoms

Re: A close contact with H7N9 infected with the fever and other symptoms

[Source: Centre for Health Protection, Hong Kong PRC SAR, full text: (LINK).]


Notification of three more human cases of H7N9 in Shanghai


The Centre for Health Protection (CHP) of the Department of Health received notification from the National Health and Family Planning Commission (the Commission) tonight (April 4) concerning three more confirmed human cases of influenza A (H7N9).

A CHP spokesman said the three cases involved a 67-year-old woman, who is in critical condition; a 4-year-old boy, who is in satisfactory condition; and a 52-year-old female patient who passed away yesterday (April 3).

Laboratory tests on the three patients' specimens by the Mainland health authorities yielded a positive result for H7N9.

According to the Commission, no epidemiological link between the three cases was identified.

So far, except a close contact of the 52-year-old female patient developed fever and runny nose, no abnormality was detected among the other 51 close contacts of three cases.
Click to expand...

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Re: China - New H7N9 Cases Confirmed and Suspected for April 4, 2013 - 3 new cases (total=14), 3 new deaths (total=6)

Re: China - New H7N9 Cases Confirmed and Suspected for April 4, 2013 - 3 new cases (total=14), 3 new deaths (total=6)

hat tip Diane Morin

Case #10 died today :(

Notification of two human cases of H7N9 in Zhejiang and Shanghai
April 4, 2013

Hong Kong (HKSAR) - The Centre for Health Protection (CHP) of the Department of Health received notification from the National Health and Family Planning Commission (the Commission) today (April 4) concerning two confirmed human cases of influenza A (H7N9).

A CHP spokesman said the case in Zhejiang was a 64-year-old man, who passed away today. As regards the case in Shanghai, the 48-year-old male patient died yesterday (April 3).

more...

http://7thspace.com/headlines/43538...n_cases_of_h7n9_in_zhejiang_and_shanghai.html
 
Re: China - New H7N9 Cases Confirmed and Suspected for April 4, 2013 - 3 new cases (total=14), 2 new deaths (total=6)

We are grateful to the samplers, the depositing labs and the GISAID consortium for making the small batch of evaluation material available on 2013-03-31 during this zoonotic epidemic emergence of H7N9 that has the very unfortunate combination of a High Case Fatality Rate and Low clinical intervention effectiveness [GISAID Citations].

The H7N9 human cases show clinically and experimentally-confirmed Gain of Function traits on a minimum of 3 gene segments:

  • Hemagglutinin 226L
  • Neuraminidase aa69-73 stalk deletion (15 base)
  • Polymerase Basic 2 627K
The H7N9 sequences are related at the polymorphism level to widely circulating human virus patterns including pH1N1, sH3N2 and to fatal human H5N1. Each component of the H7N9 human cases carries sub-segment genetics that have seen mammalian adaptation, including the external proteins, Hemagglutinin and Neuraminidase.

An up-to-date and comprehensive follow-up evaluation for each HA polymorphism found on the 3 human H7N9 sequences was provided Wednesday, 2013-04-03, demonstrating the Cross Serotype Homology details. The preliminary H7N9 Novelty Evaluation and Relationship Potential to pH1N1 with detailed Hemagglutinin amino-level polymorphism surfacing was made available for preview on 2013-03-31, formalised at midnight and is now being versioned.

Genetic specifics concerning animal origins and human / mammal adaption are under analysis. The full text of those intermediate reports are currently in pre-publication viewing status and are available at the following links. These compilations will be updated as labs release new sequences.


Additional sequences from early emergence fatal and recovered cases are critical to understanding the immune dynamics required for establishing a bulkhead toward the protection of public health.
 
Re: China - New H7N9 Cases Confirmed and Suspected for April 4, 2013 - 3 new cases (total=14), 2 new deaths (total=6)

machine translated, detail of yesterday's cases in Shanghai.

Shanghai new confirmed cases of human infection with the H7N9 avian flu in four cases


Time :2013 -04-05

As of today (4) 21, the city also confirmed four cases of human infection with the H7N9 avian influenza. Up to now, Shanghai has found six cases of human infection of H7N9 avian influenza confirmed cases, including 4 deaths in the other two cases is where One example is a child, minor illness, is recovering. There was no correlation between the six cases.
Additional two cases of deaths as follows:
patients with a reservoir, male, 48 years old, Jiangsu Rugao person, mainly engaged in chickens and ducks transported. Patients with symptoms such as cough, sputum, March 28 to April 1 fever and went to a private clinic. After exacerbations, and went to the emergency department of Tongji Hospital on the morning of April 3 4:55. Rescue by experts, the end result of his condition deteriorated sharply, rescue invalid death On the morning of 7 53. At 10:30 on April 4, the Shanghai Center for Disease Control reports the results of laboratory tests for the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the afternoon of April 4, the Shanghai Municipal Health and Family Planning Commission organized municipal clinical expert group to discuss the deaths of experts based on the clinical performance of laboratory testing and epidemiological data to diagnose the cases human infection of H7N9 avian influenza. After investigation, the close contacts of the cases to a total of eight people, with fever or respiratory symptoms were not found until now.
Patients with a particular female, 52 years old, the people of Shanghai, retirement. Patients with low fever on March 27 and March 29 to Changning District Central Hospital emergency room treatment, due to sicker to the Huashan hospital on April 1, April 2 again to Huashan hospital, admitted into the Emergency Room, April 3 after she died. In the afternoon of April 4, the Shanghai Center for Disease Control reports the results of laboratory tests for the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the municipal clinical expert group to discuss the deaths, the diagnosis of the cases of human infection of H7N9 avian influenza. After investigation, a total of 31 close contacts of the case, until now, only a fever, runny nose, itchy throat, and other symptoms, isolation and treatment have been transferred to the Shanghai Public Health Clinical Center at 6:53 p.m. on April 4, other close contacts were not found to have a fever or respiratory symptoms.
Another two cases are the cases where the situation is as follows:
patients with Jo, female, 67 years old, the people of Shanghai, retirement. Patients March 22, a sore throat, cough, sputum, fever, chills symptoms, March 24 to Dongfang Hospital for treatment, March 25, 26, 27 for three consecutive days to Yan Chai Hospital for treatment, March 27 went Ruijin Hospital emergency department, admitted into the Department of Respiratory ICU, is currently in critical condition. At 6:40 on April 2, Huangpu District CDC detection of influenza virus universal primer nucleic acid positive, Shanghai Municipal Center for Disease Control will soon specimen to CDC for further testing. In the afternoon of April 4, the Shanghai Municipal Center for Disease Control reports the results of laboratory testing for the H7N9 avian influenza virus nucleic acid positive. In accordance with the relevant requirements, the municipal clinical expert discussion of the cases, the diagnosis of the cases of human infection of H7N9 avian influenza confirmed cases. After preliminary investigation, the close contacts of the cases a total of three people with fever or respiratory symptoms, were not found until now.
Patients Lee, male, 4 years old, the people of Shanghai, the kindergarten children. Children on March 31 fever 39 ℃, runny nose symptoms, go to the city and six hospitals Jinshan Branch on April 1 treatment. April 3, six hospitals Jinshan Branch of the children go to the pediatric hospital isolation and treatment of children generally in good condition, the body temperature of 36 ? C. In the evening of April 2, the Shanghai Center for Disease Control reports the results of laboratory tests for the H7N9 avian flu virus nucleic acid positive, about to the specimen to CDC for further testing to confirm. In accordance with the relevant requirements, the afternoon of April 4, the municipal clinical expert group of the cases discussed diagnosis of the cases of human infection of H7N9 avian influenza. After investigation, the close contacts of the cases a total of 18 people have a fever or respiratory symptoms were not found until now.
According to the National Health and Family Planning Commission recently issued a "human infection with the H7N9 avian flu clinic program (1) in 2013," and "on the strengthening of human infection with the H7N9 avian flu prevention and control of notice" from April 3 people infected with the H7N9 avian influenza cases combined municipal clinical expert epidemiological history, clinical symptoms and signs, laboratory test results and other information consultation to determine. The national CDC issued the H7N9 avian influenza virus detection reagents to clear samples by City CDC detection.
Once the symptoms of fever, cough, acute respiratory infections, especially high fever, breathing difficulties, should be approaching the hospital for treatment, be sure to tell the doctor whether contact with sick poultry, etc., prior to the onset and treatment and medication under the guidance of a doctor.

(Source: Shanghai Municipal Health Bureau website)
http://www.chinacdc.cn/jkzt/crb/rgrgzbxqlg_5295/rgrqlgyp/201304/t20130405_79490.htm
 
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