China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://news.xinhuanet.com/english/2008-05/20/content_8213204.htm

Kindergartens in worst-hit China city of viral outbreak to reopen
www.chinaview.cn 2008-05-20 12:09:08

HEFEI, May 20 (Xinhua) -- Kindergartens in Fuyang City, the worst-hit Chinese city of hand-foot-mouth disease (HFMD), will resume classes on the coming Children's Day on June 1, as the authorities considered the situation has been brought under control.

The viral epidemic mainly caused by intestinal viruses of EV71 and the Coxsackievirus (Cox A16) takes toll on children. Most kindergartens suspended classes after the city, with a population of 9.3 million reported the country's initial HFMD outbreak in April.

As of May 18, 1,116 HFMD patients remained in hospitals in Fuyang, two of whom were still in critical condition, and 17 others are under intensive care, said sources with the city's health bureau.

However, no fatalities of the viral epidemic have been reported for the eighth consecutive day in the city in east China's Anhui Province, as of Tuesday.

The incidence of HFMD in Fuyang was on decline, with discharged patients outnumbering those checking in to hospitals for the first time on May 9.

The government sources said that 72 new infection cases were reported on May 18, and 88 HFMD patients were discharged on the same day.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://www.shanghaidaily.com/sp/article/2008/200805/20080521/article_360306.htm
Slight increase in virus cases
By Cai Wenjun 2008-5-21

SHANGHAI reported 2,138 cases of hand, foot and mouth disease from last Monday to Sunday, a small increase over the previous week, the Shanghai Health Bureau said yesterday. There were no fatalities.

Most of the cases were children between one and six years old. Those living on the outskirts had a higher incidence than children in downtown areas and more migrant children suffered the disease than local children.

The city had three minor outbreaks of the disease at local kindergartens last week and each outbreak involved about 10 cases, officials said.

The Shanghai Center for Disease Control and Prevention conducted checks on 81 HFMD cases detected last week, confirming 27 patients infected with Enterovirus 71, or EV71, and 10 patients with Cox Asckievirus A16, another main intestinal virus leading to HFMD. None of the 37 cases had serious symptoms.

"The city will further enhance control and prevention of HFMD and focus on disease prevention at kindergartens, which are ordered to conduct effective daily checkup and disinfection," said Song Guofan, a health bureau official. "We are concerned that a growing number of children staying at home suffer HFMD, so we will carry out more education in communities. Educating adults is also important, since adults can spread the virus to children."

Local medical experts have been in Anhui Province's Fuyang, the city with the highest number of HFMD cases and largest mortality rate.

Nine pediatricians set up a 50-bed unit at Fuyang No. 2 People's Hospital on May 1.

"They saved seven dying children," Song said.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://www.flutrackers.com/forum/newreply.php?do=newreply&noquote=1&p=158263

Tibet reports two suspected HFMD cases
www.chinaview.cn 2008-05-20 23:55:02

LHASA, May 20 (Xinhua) -- Two children in Lhasa were thought to have contracted hand-foot-mouth disease (HFMD), said a spokesman of the regional disease prevention and control center.

Symptoms of the contagious disease were displayed by a 5-year-old boy in a kindergarten in Lhasa on Sunday, said Rao Ruodeng, director of the regional disease prevention and control center on Tuesday.

The only information about the other case was the location, in Zhoulin County.

The children were receiving treatment in isolation wards and were both in stable condition.

"The health bureau has sent blood samples to the state disease prevention and control center for diagnosis," Rao said.

The kindergarten, where the 5-year-old had studied, had its classrooms and facilities sterilized to prevent further infection.

On May 16, a 22-month-old girl from Ganzhou, a city in the eastern Jiangxi Province, died of HFMD in a hospital, pushing up the national toll from HFMD to 43.

According to the Ministry of Health, HFMD, an epidemic disease that mainly affects children, can be caused by a host of intestinal viruses, but EV71 and the Coxsackievirus (Cox A16) were the most common.

HFMD usually starts with a slight fever followed by blisters and ulcers in the mouth and rashes on the hands and feet. Those with EV71 often show serious symptoms. It can also lead to meningitis, encephalitis, pulmonary edema and paralysis in some children. There is no vaccine.

 

[Giuseppe]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

[WHO Document - May 21, 2008]
Executive Summary

In late March 2008, a hospital clinician was alarmed by the occurrence of 3 consecutive deaths of pre-school children presented with severe pneumonia and rapid deterioration in Fuyang City, Anhui Province.

Up until mid-April, 15 children have died of similar severe illness.

Through an investigation conducted by local and national experts, the disease was confirmed on April 23 as hand, foot and mouth disease (HFMD) caused by enterovirus 71 (EV71) based on epidemiological, clinical, laboratory and pathological evidence.

Retrospective case investigation revealed that a simultaneous outbreak had occurred in the same area with children presenting skin rashes and blisters over hand, foot, and mouth.

Anhui is an inland province located in the central part of Southeastern China.

Fuyang City is located in the Northwest region of Anhui Province and has a total population of 9.76 million.

The city covers a total area of 9,700 km2 with one of the highest population densities in Mainland China (1,000 per square km).

In Fuyang City, from March 1 to May 9, there have been 6,049 reported cases of HFMD of which 353 were severe and 22 were fatal (case fatality rate 0.4%).

Retrospective case-finding identified 302 cases that occurred between March 1 and April 22, and revealed that the first case occurred as early as March 10.

The number of cases according to date of onset began to increase in early April, and peaked on April 28.

The number of reported HFMD cases in Fuyang City decreased after
May 5.

Among the 6,049 reported cases in Fuyang City the gender ratio was 1.9:1. The age range varied between 28 days to 18 years of age, with 78% of the cases being 3 years of age or younger.

All districts/counties in Fuyang City reported HFMD cases, with more than half the cases concentrated in 3 districts (Yingzhou, Yingdong and Yingquan).

Epidemiological investigation revealed no contact between the 22 fatal cases, but environmental investigation of the cases' households revealed poor hygienic and sanitary conditions among these families.

The clinical symptoms of the mild HFMD cases are those typical for the disease: rashes on hands and feet, mouth and buttocks, fever and general malaise.

All fatal cases presented an acute onset of fever and influenza-like-illness without catarrhal syndrome.

The cases' condition rapidly deteriorated, developing tachypnea, cyanosis, and some presented seizures.

All fatal cases died of serious complications such as neurogenic pulmonary oedema due to EV-71 infection.

Testing initial cases for a variety of diseases, including seasonal and avian influenza A/H5N1 and SARS did not reveal any conclusive results.

Subsequently, additional testing by Chinese Center for Disease Control and Prevention (CDC) was performed and several expert consultations were conducted.

On April 23, a variety of specimens such as pharyngeal swabs, lung puncture fluid, lung tissues, and blood from 5 out of 12 fatal cases (42%), tested EV71 nucleic acid positive by RT-PCR. EV71 genotype C4 viruses were isolated from specimens of both mild and fatal cases.

These sequences from mild and fatal cases exhibited high homogeneity.

Isolated EV71 virus strain gene sequences were uploaded to GenBank on May 7.

From January 1 to May 9, 2008, 61,459 HFMD cases and 36 deaths were reported through the disease reporting system in Mainland China.

The number of reported cases increased sharply after the disease became notifiable on May 2, and with cases being reported from nearly all provinces.

The 5 provinces with the highest number of reported cases are Guangdong (11,374), Anhui (9,235), Zhejiang (6,134), Shandong (4,566) and Henan
(3,230).

Because of the change in reporting policy and increased awareness of the general public about the disease, it is expected that there will be an increase in the number of reported HFMD cases in the upcoming weeks and months from Anhui Province and the rest of China.

Non-polio enteroviruses are common and exist worldwide.

Although infection often has no symptoms and goes unnoticed, these viruses are also associated with occasional outbreaks in which a larger-than-usual number of patients develop clinical disease, sometimes with
fatal consequences.

The initial high case fatality rate of the Fuyang City outbreak, 2.9% (18/610) from March 1 to April 23, was likely attributed to the following factors: rapid disease progression, late clinical presentation, and limited local medical capacities.

Although there is no specific treatment for enterovirus infections and a vaccine is not currently available, once the aetiology of the disease was known and early treatment was provided to the severe patients, the case fatality rate decreased considerably to 0.07% (4/5439) from April 24 to May 9, due to enhanced surveillance and implementation of prevention and control measures.

There have been a number of outbreaks of EV71 HFMD in the Asia-Pacific region since 1997.

In China, outbreaks have been reported in Taiwan Province in 1998 (>100,000 cases and 78 deaths) and in Shandong Province in 2007 (38,606 cases and 14 deaths).

The Government of China has shown its strong technical and political commitment to control the disease in Anhui and other provinces. In addition to enhanced surveillance, training was provided to clinicians and public health workers to improve the treatment success rate by increasing early identification and treatment of severe HFMD patients.

Guidelines were written to enable early admission of severe cases to the hospital, and critical cases to the paediatric ICU. After that, the case fatality rate has decreased substantially. In addition, to prevent HFMD, the Ministry of Health started a nationwide health campaign, stressing the need for personal hygiene, in particular hand washing practices.

In the future, China is devoted towards enhancing the above-mentioned measures for the prevention and control of HFMD in China. As part of the efforts to implement the International Health Regulations, IHR(2005), China will further strengthen the early warning system by immediate notification of clustering of clinically abnormal and severe cases, as well as increasing international collaboration and information exchange.
(...)
-
A. Laboratory testing of fatal cases
Between March 31 and April 16, the Anhui CDC tested 53 specimens (including whole blood, blood serum, pharyngeal swab and tissue samples), collected from fatal HFMD cases, and tested negative for the presence of seasonal influenza, avian influenza A/H5N1, Severe Acute Respiratory Syndrome (SARS) .

On April 18, the Institutes of Infectious Diseases and the Viral Diseases Prevention and Control of Chinese CDC received from Anhui CDC the previously collected specimens: pharyngeal swabs, lung puncture fluid, lung tissues, and blood. Laboratory testing for the presence of bacteria and virus was performed immediately on these samples.

Specimens from 5 out of 12 fatal cases (42%) tested EV71 nucleic acid positive by RT-PCR. Of these 5 EV71 positive fatal cases, the lung tissue specimen tested EV71 positive for 1 case, and for another case, the intestinal lymph nodes, cerebrospinal fluid, spleen, thymus, kidney, brain,
heart and lung specimens were EV71 positive.

For the other 3 cases, the pharyngeal swabs were EV71 positive.

Viral isolation was conducted on 6 different types of specimens (including lung tissue, mouth efflux, brain tissue and pharyngeal swab) collected from 3 fatal cases. For all 6 specimens, the nucleotide sequencing and neutral antibody tests revealed the presence of EV71 virus.

B. Autopsy findings
The autopsy on 3 fatal cases performed by the Medical School of Beijing University, found mainly changes in the brain, lung, heart and lymphatic system.

There were cases of
* severe brain oedema;
* lung congestion/pulmonary oedema, no significant lung inflammation, no significant bleeding;
* cardiac enlargement;
* hypertrophy of tonsils, thymus and lymph nodes;
* spleen enlargement; normal kidney, liver and gastrointestinal organs.

The autopsy findings were overall consistent with the clinical manifestations and disease progression and strongly suggest viral infection.
(...)
-

http://www.wpro.who.int/NR/rdonlyres/591D6A7B-FB15-4E94-A1E9-1D3381847D60/0/HFMDCCDC20080515ENG.pdf
-------

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://news.xinhuanet.com/english/2008-05/23/content_8237455.htm

Hand-foot-mouth disease declining in China's Anhui Province
www.chinaview.cn 2008-05-23 18:49:35

HEFEI, May 23 (Xinhua) -- The outbreak of hand-foot-mouth disease (HFMD) has ebbed in east China's Anhui Province, which was worst-hit by the viral epidemic since April, the provincial department of health said on Friday.

The number of cases reported everyday dropped from a peak of 1,160 on May 1 to 153 on May 21, and no further deaths had occurred over the past 12 days, the department said in a circular.

It said 734 people were still hospitalized in Anhui, including 10 in serious or critical condition.

Doctors successfully treated 10,696 HFMD patients in Anhui, although 26 died in the outbreak.

Kindergartens in Fuyang City, the worst-hit city, will resume classes on Children's Day -- June 1 -- as the authorities considered the situation was under control.

According to the Ministry of Health, HFMD can be caused by a host of intestinal viruses, but EV71 and the Coxsackievirus (Cox A16) were the most common.

HFMD usually starts with a slight fever followed by blisters and ulcers in the mouth and rashes on the hands and feet. Those with EV71 often show serious symptoms. It can also lead to meningitis, encephalitis, pulmonary edema and paralysis in some children. There is no vaccine.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://ap.google.com/article/ALeqM5jwzLn2zcamjQWx4x-pVFGvVFFtAAD90RHT380
Chinese officials: child virus outbreak eases


BEIJING (AP) ? The spread of a virus that has sickened more than 24,000 people and killed dozens across China is slowing in the province where the outbreak was first reported, a state-run news agency said Friday.

The health department in eastern Anhui province said no deaths from the hand, foot and mouth disease virus had occurred there in the past 12 days, the Xinhua News Agency reported.

The report said the number of new cases reported daily had dropped from a high of 1,160 on May 1 to 153 on May 21. It said 10 people were still in serious or critical condition.

The World Health Organization could not verify the figures and whether the decline was significant.

Gregory Hartl, a spokesman for WHO in Geneva, said the global health body had received no details on the situation since May 19. He said determining whether a drop in cases was meaningful would be difficult because the disease was not identified until the middle of the outbreak when it was already spreading rapidly.

"It will take some time to iron out the numbers," Hartl said.

He said the picture was further complicated because under normal seasonal patterns the virus usually peaks in the hot months of June and July.

Anhui was the worst-hit province with 26 deaths, and the outbreak was first reported there in March. Most cases of hand, foot and mouth disease in China this year have been blamed on enterovirus 71, which usually infects children.

The virus, a major concern as Chinese authorities prepare for the Aug. 8-24 Olympics, has killed at least 43 people across China, but the state health ministry hasn't updated that number since May 16. The ministry didn't respond to a faxed request this week for an updated number, and a call to the ministry Friday night was not answered.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://www.sciam.com/article.cfm?id=china-tries-to-halt-hand-food-mouth-disease

May 27, 2008
China Tries to Halt Spread of Hand, Foot and Mouth Disease
The contagious viral malady has left 42 children dead and infected 30,000 across Asia

By David Biello

SHANGHAI?Chinese authorities have launched a nationwide public hygiene campaign in an effort to combat the spread of hand, foot and mouth disease (HFMD), which has killed 42 children and infected at least 30,000 youngsters throughout Asia since the end of April. The disease, caused by an unusually virulent strain of the intestinal flu known as enterovirus 71 (EV71), so far has spread from Mongolia to Vietnam, including most parts of eastern China, and health officials warn that the situation could get worse as the disease usually peaks during the summer heat of June and July. Already, Mongolia has shut all kindergartens and primary schools as a result of the spreading outbreak.

The hardest hit areas in eastern China have been in Anhui Province, especially the city Fuyang, where 23 died, and even Beijing was not spared: two children, one a resident and one a visitor, died from the disease last week, whose symptoms include a mild fever, rash on the hands and feet and open sores in the mouth. In the most severe cases it can lead to a heart and lung infection (pulmonary edema) as well as inflammation of the brain lining (meningitis) or of the brain itself (encephalitis)?conditions that can result in paralysis or death.

Health officials here have ordered residents, schools and business to take steps designed to prevent the disease's spread, including sterilizing furniture and toys with alcohol wipes as well as keeping symptomatic children at home. The national government also ordered kindergarten and primary schools to check kids twice daily for signs of the illness. In fact, health officials have ordered schools to close for two or three weeks if any child attending becomes severely sick or if more than two cases occur in one class.

Shanghai has had nearly 2,000 cases of the disease so far this year. "Until now, the number of deaths caused by hand, foot [and] mouth disease in Shanghai [had been] zero," Fang Weimin, director of the Health Supervision Agency of the Pudong New District of Shanghai, told me through my translator. "The education department should do the educational work to enhance the awareness and alertness of related people" to make sure that parents know precautions to take to prevent the disease and how to recognize symptoms in affected kids.

The disease is typically allowed to run its course and does not usually kill those infected, according to the U.S. Centers for Disease Control (CDC). Those afflicted are most commonly the poorest of the population, such as workers who have emigrated to the booming cities and then must pay hundreds of dollars (thousands of yuan) for treatment or, in the worst cases, funerals.

The English-language newspaper Shanghai Daily reported, for instance, that 31-year-old migrant worker Chen Weiming in Guangzhou, who earns just $145 (1,000 yuan) a month, had to borrow money from his family to scrape up $245 (1,700 yuan) for his four-year-old daughter's funeral. He also cannot afford the $720 (5,000-yuan) treatment that saved his seven-year-old and 18-month-old daughters, Shanghai Daily reported and therefore cannot take custody of them from the hospital until he can pay the fee.

The World Health Organization and the U.S. Department of Health and Human Services are helping the Chinese track the source of this year's unusually deadly outbreak and map its spread. The U.S. was the first country to identify the EV71 virus as one of the culprits behind this disease in 1969. But this outbreak is also being caused, in some cases, by another enterovirus?coxsackievirus A16, according to Shanghai authorities. The CDC considers the A16 virus the most common cause of HFMD.

page 2:

Chinese authorities are also working on developing a vaccine against it, but do not expect to have one ready anytime soon. "This infectious disease usually starts in May and reaches its peak in July," Sun Shuguang, a mouth disease specialist, or stomatologist, at the Medical Center of Jingan District in Shanghai said through my translator. In lieu of a vaccine, he recommends that people take extra care to eat right to keep their immune systems strong, wash their hands regularly, and make sure their surroundings are sanitized.

 

[Giuseppe]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Post #247: (WHO update)
(...)
From January 1 to May 9, 2008, 61,459 HFMD cases and 36 deaths were reported through the disease reporting system in Mainland China.
(...)

 

[Treyfish]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

At the airport "Koltsovo" toughened measures in response to the epidemic enterovirusnoy infection in China

27/05/2008 11:58:00​

27/05/2008 11:58:00


EKATERINBURG, May 27. In Ekaterinburg airport "Koltsovo" toughened measures in response to the epidemic enterovirusnoy infection in China. This is a correspondent today. ITAR-TASS reported to FSIS in the management of the Sverdlovsk region.
In particular, paragraph passes through the state border at the airport tightened antiepidemic control readiness of aircraft basic airline, transit and charter flights, arriving and departing to China and countries in south-east Asia. To step up activities to identify lihoradyaschih passengers arriving from China. "Among other things, a training aircraft crews of epidemic when determining a patient on board the aircraft. There is also monitoring the tourist firms involved in the implementation stays in Southeast Asia, to provide passengers information on the epidemiological situation in the countries of the anticipated holiday.
Currently, China has reported more than 27.5 thousand cases, the deaths of 39 children. Ongoing further increase in morbidity, which is projected to reach the highest point in June and July this year. Recovery remains the epicentre of morbidity Fuan city of the eastern province of Anhui. :tiphat: http://translate.google.com/transla...8%D1%82%D0%B0%D0%B9+2008&sl=en&tl=ru&start=30

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://news.xinhuanet.com/english/2008-06/06/content_8320906.htm

Six punished for fatal HFMD case in China's Hubei Province
www.chinaview.cn 2008-06-06 13:10:59

WUHAN, June 6 (Xinhua) -- Authorities in central China's Hubei Province have penalized six doctors and officials for mishandling a hand-foot-mouth disease (HFMD) case in which a child from Xianning City died, official sources said on Thursday.

The Chibi Municipal Health Bureau revoked the license of Huang Yingjun, a doctor with the Quankou Clinic in Guantangyi Town, Chibi city, who was said to have delayed the transfer of the patient to the county hospital.

The patient, surnamed Xie, came to the hospital on May 10 with a fever and cough. The symptoms were diagnosed by Huang as a cold. Xie was treated at the clinic for two days before being referred for further care.

The head of the clinic, Li Gexian, was dismissed for dereliction of duty.

On May 12, when the patient sought treatment at the Xian'an District Women and Children's Hospital and Dingsiqiao Township Hospital, doctors did not take the child's medical history or make an accurate diagnosis, nor did they refer the patient to other hospitals in a timely manner.

Wu Changqing, deputy head of the Xian'an hospital and Zhang Yinghua, deputy head of the Dingsiqiao hospital, were reprimanded for dereliction of duty. Lei Qing, a pediatrician at the Xian'an hospital, was dismissed and Wu Yuhua, a doctor at the Dingsiqiao hospital, was given a demerit.

Xie died after eventually being transferred to Pufang Hospital.

Both EV71 and Cox A16 can cause HFMD, which usually starts with a slight fever followed by blisters and ulcers in the mouth and rashes on the hands and feet.

Those sickened by EV71 often show serious symptoms. It can also lead to meningitis, encephalitis, pulmonary edema and paralysis in some children. There is no vaccine.

China experiences summer outbreaks of the disease. The HFMD toll this year was 43 as of May 16, with thousands having been infected, according to Xinhua's tally of local official results.

 

[sharon sanders]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

hat tip Treyfish -

:2008-06-10
中国手足口病病例每日报告3922宗广东居首 China Hand, Foot and mouth disease cases reported daily in Guangdong top 3922
星岛环球网www.stnn.cc Sing Tao Global Network www.stnn.cc
【星岛网讯】安徽省阜阳市2008年3月份发生了较大规模的手足口病疫情，中国其他一些地区也出现了手足口病发病病例增加的趋势。 [Sing Tao network - in Fuyang City of Anhui Province in March 2008 in the large-scale hand-foot-mouth disease epidemic, other parts of China have also emerged hand, foot and mouth disease cases increase. 自5月14日起，每日报告病例数为6月5日的3922人，报告发病数居前五位的省份是广东、浙江、河北、山东和湖南。 Since May 14, the daily reported number of cases for June 5 in 3922, the incidence of the top five provinces are Guangdong, Zhejiang, Hebei, Shandong and Hunan.
http://64.233.179.104/translate_c?hl=en&langpair=zh%7Cen&u=http://www.stnn.cc/society_focus/200806/t20080610_792918.html

 

[Commonground]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

China's May report of hand, foot and mouth disease outbreak killed 40 cases Wenzhongyoujiang
(Boxun - June 10, 2008 reprint)
Source:中新网
State Ministry of Health spokesman Mao Qun said of today: this year at 0:00 on May 1 to May 31, 24, the Chinese mainland reported a total of 176,321 cases of Hand, Foot and mouth disease, 40 cases of death, the Hand, Foot and mouth disease epidemic Wenzhongyouxiang.
-snip-
http://64.233.179.104/translate_c?h....com/news/gb/china/2008/06/200806101808.shtml

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://news.xinhuanet.com/english/2008-06/10/content_8341269.htm

Health official: China HFMD outbreak peaks in May
www.chinaview.cn 2008-06-10 19:01:43

BEIJING, June 10 (Xinhua) -- China reported more than 176,000 cases of hand-foot-mouth disease (HFMD) last month, but the outbreak peaked on May 14, Ministry of Health spokesman Mao Qun'an told reporters here Tuesday.

Daily reported cases declined from 11,501 at the peak to 3,922 on June 5, Mao said.

Central Anhui Province, which first reported the outbreak of HFMD, had 10,700 cases in May including four deaths, according to Mao.

The worst-hit provinces and regions were Guangdong, Zhejiang, Hebei, Shandong and Hunan, he said.

The disease was also found in regions hit by the devastating May 12 earthquake but, earlier this month, Mao told the press that it had been brought under control.

"The Ministry of Health required that HFMD cases must be reported since May 2 this year," said Mao, "Any HFMD case in the quake-hit areas will be reported immediately through our reporting system."

Nurseries in Fuyang City, Anhui, the worst-hit city, resumed classes on Children's Day (June 1) as health authorities considered the situation was under control.

Between late March and the end of April, the city reported about 22 death cases of HFMD but, in May alone, it reported 4,444 cases, including one death.

HFMD can be caused by a host of intestinal viruses, but EV71 and the Coxsackievirus are the most common.

HFMD usually starts with a slight fever followed by blisters and ulcers in the mouth and rashes on the hands and feet. Those with EV71 often show serious symptoms. It can also lead to meningitis, encephalitis, pulmonary edema and paralysis in some children. There is no vaccine.
Editor: Bi Mingxin

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://www.shanghaidaily.com/sp/article/2008/200806/20080617/article_363510.htm

Boy is first HFMD fatality in Shanghai
By Christine Cai | 2008-6-17 | NEWSPAPER EDITION


SHANGHAI Health Bureau reported a fatal case of hand, foot and mouth disease yesterday. The dead boy is the first person to have died of HFMD in the city, where the epidemic has been controlled.

The two-year-old identified as Yu died at Shanghai Public Health Center on Saturday. The boy, who was from Shangshui County in Henan Province and living in Songjiang District, broke out in a rash on his hands and feet for three days. He was sent to the hospital on Saturday night.

He was confirmed as having HFMD with viral encephalitis and received hospital treatment. But his condition deteriorated and he died hours after arriving at the hospital, officials said.

Medical experts are investigating the case.

This year the city reported 10,340 cases of HFMD.

Most of the sufferers were children aged up to six. All 18 districts and Chongming County have reported detection of the disease.

The bureau said it was maintaining strict inspections and monitoring of the disease. All kindergartens are required to carry out daily morning checks and disinfection procedures.

Since an increasing amount of children living at home were reported to have caught the disease, the bureau said it would enhance education to promote knowledge of HFMD and prevent the virus spreading from adults to children.

"Educating adults to adopt good habits regarding personal hygiene is very important," said Song Guofan, an official from Shanghai Health Bureau. "It is known adults can spread the virus to children without developing symptoms themselves."

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://news.xinhuanet.com/english/2008-06/17/content_8384239.htm

Shanghai reports first child death of hand-foot-mouth disease
www.chinaview.cn 2008-06-17 10:13:28

SHANGHAI, June 17 (Xinhua) -- Shanghai Health Bureau on Tuesday confirmed the city's first child death of hand-foot-mouth disease (HFMD).

The two-year-old boy was sent to the Shanghai Public Health Clinic Center for treatment on the evening of May 14, where he was diagnosed as having HFMD.

Emergency treatment failed and he died a few hours later, according to the bureau.

The child, a native in north China's Henan Province, lived with his family in Songjiang District of Shanghai, said a bureau statement.

Medical experts were still studying the case.

Shanghai reported 10,340 HFMD cases in the first five months. The city is not on the Health Ministry's list of the regions worsthit by the epidemic.

The ministry reported earlier last week that there were more than 176,000 HFMD cases reported nationwide last month. Daily reported cases declined from 11,501 at the peak on May 14 to 3,922 on June 5.

Central Anhui Province, which first reported the outbreak of HFMD, had 10,700 cases in May including four deaths.

The worst-hit provinces were Guangdong, Zhejiang, Hebei, Shandong and Hunan, according to the ministry's report.

Nurseries in Fuyang City, Anhui, the worst-hit city, resumed classes on Children's Day (June 1) as health authorities considered the situation was under control.

HFMD can be caused by a host of intestinal viruses, but EV71 and the Coxsackie virus are the most common. Those with EV71 often show serious symptoms. It can also lead to meningitis, encephalitis, pulmonary edema and paralysis in some children. There is no vaccine.
Editor: Du Guodong
Related Stories

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://www.shanghaidaily.com/sp/article/2008/200806/20080619/article_363774.htm

Disease claims 6 in Zhejiang

By Cyril Li | 2008-6-19

SIX people in east China's Zhejiang Province had died of hand, foot and mouth disease by Monday, according to the provincial health department.

The province has recorded 20,503 cases.

Wenzhou, Hangzhou, Ningbo, Shaoxing and Jinhua are the five cities with the most cases. Wenzhou, which topped the list, has recorded 6,433 cases.

Hospitals at Zhejiang now have 374 patients in wards, and 32 reported to be in a critical condition.

The Shanghai Health Bureau reported a fatal case of hand, foot and mouth disease on Monday. The dead boy was the first person to have died of HFMD in the city, where the epidemic has been controlled.

This year Shanghai reported 10,340 cases of HFMD.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://big5.xinhuanet.com/gate/big5/www.js.xinhuanet.com/misc/2008-06/18/content_13574474.htm

Google translation:

Zhejiang: Up to 16 reports a total of 20,503 cases of Hand, Foot and mouth disease killed six cases
Dazhong Xiao [name]

June 18, 2008 10:17:24
Source: Xinhuanet

As of June 16, Zhejiang Province reported a total of 20,503 cases of Hand, Foot and mouth disease. The number of cases before the five cities are: Wenzhou (6,433 cases), Hangzhou (3,365 cases), Ningbo (2,843 cases), Shaoxing (2,062 cases) and Jinhua (1,648 cases). The number of cases before the five counties (cities, districts) were: Ryan (1,281 cases), Ouhai (1,052 cases), Lucheng (1,021 cases), Yuhang (934 cases) and Yueqing (823 cases). Report of six cases of death, respectively, Cangnan County, Shaoxing County, three counties, Wenling City, Hangzhou, the case of Zhuji City. Hospitalized cases are reported 374 cases, 32 cases of severe cases, the total number of detected 542 cases of infection EV71.

Although the cause hand, foot and mouth disease pathogens, multiple communication channels, the crowd generally susceptible, but this is an anti-controllable children of common infectious diseases. Most of the patients in less serious clinical symptoms, 7-10 days after the rest can be self-healing, only a very small number of patients in particular, the following three-year-old poor immune function, low birth weight, premature infants, breast-feeding inadequate or non-breast-feeding and nutrition Poor children vulnerable to severe complications and even death. Therefore, should pay close attention to early symptoms of critical recognition, especially children under the age of three, if there is sustained high fever not to rash was not obvious or rash, vomiting, convulsion and other symptoms, should be immediately sent to the local county-level hospitals for treatment work . At the same time to observe good personal hygiene is the key to controlling the disease. (Wang Chen Li Jie Zhanya Yangqing Shen Shu-fen)

Related News

Hangzhou additional 416 cases a week of hand-foot-mouth disease

Yesterday, Hangzhou City Health Bureau reported on the week to the Hand, Foot and mouth disease epidemic. From at 9:00 on June 11 to at 9:00 on the 17th, Hangzhou new cases of Hand, Foot and mouth disease in 416 cases, the average daily new cases of clinical diagnosis of 69 cases. 42 cases are in-patients, Yuhang, Xiaoshan District have a case of severe cases, the current conditions are stable. June 11 Yuhang District in case of Hand, Foot and mouth disease deaths.

Hand, Foot and mouth disease cases have occurred after death, Hangzhou strengthened the prevention and control of the overall layout. Labor and Social Security Bureau formulated and issued documents, in the city within the local and foreign workers and their children free of charge prevention and treatment, the public can access for further policy.

Week, the city's total supervision and inspection of kindergartens, 141, 118, medical institutions.

Editor: Tangqing

 

[Commonground]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Hong Kong kindergarten unexploded hand, foot and mouth disease to be closed


[大纪元June 19 - (Ming Pao Daily News on June 19, 2008 report) Centre for Health Protection said that the proposed time and again by the hand, foot and mouth disease affected the St. James Settlement Group will be Mr Lin Jie kindergarten child care centres will be closed two Week.

St. James Settlement in Wan Chai group will be Mr Lin Jie kindergarten child care centres in the June 4 to 12 during the five students in the Hand, Foot and Mouth disease symptoms, including a five-year-old boy was confirmed on June 11 EV-71 infection 71, was admitted to Queen Mary Hospital, has now been recovered and were discharged. Other affected students were not admitted.
Center for Health Protection on June 12 to visit the school, the school under the proposal to strengthen internal cleansing. However, the Centre for Health Protection today received a further case, involving a three-year-old boy, he appeared in the June 17 hand-foot-mouth-like symptoms, is now in stable condition without hospitalization.

CHP spokesman said that as the school in strengthening infection control measures after new cases are still emerging, the proposed school will be closed for two weeks from tomorrow to July 3, in order to thoroughly disinfected.

6/20/2008 12:31:58 AM
http://translate.google.com/transla....htm&hl=en&ie=UTF8&sl=zh-CN&sl=es&tl=en&tl=en

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source:
http://big5.xinhuanet.com/gate/big5/www.zj.xinhuanet.com/newscenter/2008-06/21/content_13604047.htm

Hangzhou medical experts to the public a comprehensive analysis of hand-foot-mouth disease
-- Zhejiang channel (2008-06-21 10:14:45) Source Hangzhou Daily News Editor: Xiaoming

Since March this year, appeared in some regions of China due to intestinal virus infections caused by children with hand, foot and mouth, caused widespread concern in the community. At present, Hangzhou, hand, foot and mouth disease outbreak in a high state of dissemination. As of this week, a total of 3,365 cases, Hangzhou, hand-foot-mouth disease cases, including one case of Yuhang District have died. Since the June report of hand, foot and mouth disease, the number of cases showed slight upward trend.

Hand, Foot and mouth disease virus is how to disseminate the ? How should we prevent ? In order to give the public a correct understanding of hand, foot and mouth disease, Hangzhou City Health Bureau specially invited to the provincial director of the Center for Disease Control and Prevention Cong Liming, president of Children's Hospital Zheng-Yan Zhao, president of the hospital in six-Lou, a city hospital pediatrician Huang, director of first-mei, City Wang Jiehua Erkezhuanjia a hospital and the Municipal Public Health Bureau of Health and grassroots maternal and child health, such as the Director Zhou Hua Several experts, to the public a comprehensive analysis of hand-foot-mouth disease.

More than 20 kinds of viruses can cause hand, foot and mouth disease

Cong Liming (provincial director of the Center for Disease Control and Prevention, the chief physician):

Hand, Foot and mouth disease is a common infectious diseases, mainly caused by the intestinal virus, a fever and hand, foot, mouth and other parts of rash or herpes as the main characteristics of preschool children mainly to patients, especially children under five years old multi - Our province currently under the age of five age of onset of 86.80 percent, 2-year-old and 2-year-old accounted for 54.28 percent below. So easy to pop in the season preschools groups in the incidence of infection.

As the trigger hand, foot and mouth disease have more than 20 kinds of intestinal virus, and can not be infected, was in a life-long immunity, so there is no effective vaccine to prevent. Therefore the enhancement of health education to improve people's health awareness and self-protection ability is very important.

The vast majority of hand, foot and mouth in patients with clinical symptoms less serious, symptomatic treatment will quickly return to health, but some patients especially with three children under the age of EV71 virus, there will be some serious complications, particularly remind parents should be raised Vigilance Once a child fever and hand, foot, mouth and other parts of rash or herpes, the spirit of difference, nausea, vomiting, muscle twitching or physically jitter, such as inability to timely performance should be regular hospital.

Schools, preschools to strengthen Chen Jian, found that patients in accordance with relevant regulations after disinfection, and so do the work, when necessary, will be closed 1-2 weeks. Medical personnel in medical institutions Jiezhen hand, foot and mouth disease should be carefully observed condition and asked about history and found that hand, foot and mouth disease in particular, have three children under the age of hand-foot-mouth symptoms of the illness re-sign, should be promptly admitted to hospital for treatment. Does not have the medical institutions where conditions should be promptly referred to the children or children with pediatric specialist hospitals over the two general hospitals.

Medical deaths sometimes inevitable

Zheng-Yan Zhao (Children's Hospital president and chief physician):
On the hand, foot and mouth disease have a correct understanding, it is necessary to actively control, to the extent possible, early discovery, early diagnosis, early isolation and early treatment, but also to avoid unnecessary panic and over-stretched. The deaths occurred from the medical sense sometimes it is hard to avoid, the disease causes the one hand, children with their own growth and nutritional status is also a very important reason, in our province in the last several deaths, all children with physical Very weak. The province more than 20,000 cases in a few cases of deaths, it should be said that mortality rate is very low. Of course, do its utmost to where children are our bounden duty of the medical staff.

To critically ill patients in the early clinical manifestations, corresponding to the timely treatment, to improve the cure rate of hand, foot and mouth disease is of great significance. For children and parents, individuals, families and preschools health is the key to prevention of infection. In addition to doing a good job of health, Qin drying clothing, and more ventilation, in particular, must control their children's hands. Before meals after they wash their hands with soap or liquid to the children wash their hands. Parents, nannies and other caregivers in contact with children, changing nappies to wash their hands after handling manure, the use of infant feeding bottles, pacifiers should be cleaned before and after use. In addition, do not let children drink raw water, eat cold food, not to take children to crowded, poor air circulation in public places, avoid contact with sick children.

Parents need not panic

Lou Strong (6 City Hospital president, chief physician):

For suffering from hand, foot and mouth disease in children of parents hearts certainly very anxious, in fact, parents do not have to completely panic, the children especially in infants and young children of preschool is a lot of virus infection, the virus is the existence of the human nature of the challenge and nature of children An immunity, so it is normal to fall ill, we should correctly deal with it. Hand, Foot and mouth disease as a common diseases, frequently-occurring disease, is not there this year, our country many years ago are not as many people as frightening legend, and most patients are mild. It is precisely because of its multiple, symptoms of illness after the lighter, low mortality, the Ministry of Health until this year before its inclusion in Group C of the report infectious diseases. City hospitals treated six from the Hand, Foot and mouth disease patients, the vast majority is mild, generally about a week will be better. In the relative risk of very severe, six hospitals in the city treated patients in 688 cases, only two cases of severe, but by actively hospital for treatment, are pulled through again and again.

Hand, Foot and mouth disease incidence may be the year to summer and autumn Most of June and July for a period of high. In kindergartens and nurseries may be infected with a collective phenomenon and the family gathered incidence. The main collection - I and / or respiratory droplets spread by close contact can also be infected. Usually within one week after the incidence of infectious strongest.

Early prevention is very important.

Huang first-mei (a city hospital, director of pediatrics, chief physician):

Hand, Foot and mouth disease is caused by infection of the intestinal infectious diseases. Major violations of children. Most children with a light, only for the performance of hand, foot, mouth, a herpes hip (hand, foot and mouth disease) or herpangina, lasted about a few days for the self-limited, there can be a very small number of severe encephalitis, brain meningeal Yan, brain stem encephalitis, pulmonary edema, or pulmonary hemorrhage, the rapid progress of disease, the mortality rate high. Therefore, hand, foot and mouth disease in the early prevention is very important.

Hand, Foot and mouth disease through respiratory, intestinal and close contacts, and other communication channels, in the hope that parents maintain good personal and environmental hygiene, eating the attention of health, maintaining good ventilation, and so on the basis of the work, paying particular attention to strengthening the child Physical training and nutritional supplements to enhance immunity, to avoid exertion, Shouliang, and other factors led to the decline in immunity. If it is found that children had abnormal performance, such as the child has fever or oral herpes, hand, foot and a small rash, blisters, with child care immediately to hospital.

Community health agencies to do a good job Visit

Zhou Hua (Urban Primary Health Bureau of Health and Maternal and Child Health Director):

According to the Ministry of Health, the Provincial Health Department regulations require, the city identified in a paediatric hospital in two or more hand-foot-mouth disease as a sentinel hospital treatment. As the community health service organizations (THCs) and other grass-roots medical institutions Pediatric relatively weak force, grass-roots medical institutions is to strengthen the pre-screening of outpatients attendance at work, shall not be carried out of hand, foot and mouth disease clinic activities. Especially for children under the age of three treatment of pre-screening work, to inform pre-screening and referral records. At present, some hand, foot and mouth disease in the patient's family in order to facilitate the hope that the community health service centres (THCs) for treatment, which is not allowed.

According to "hand-foot-mouth disease in Hangzhou home isolation of patients of community management technical guidelines", community health service centres (THCs) as a community management of those responsible for street-based (township) of the hand, foot and mouth disease patients do a good job in the management of home confinement , The main task is to investigate visiting, Bing Jia disinfection, close contact tracing and retrieval, and so on around the crowd.

Most patients can be cured naturally

Wang Jiehua (City Hospital Erkezhuanjia):

Hand, Foot and mouth disease caused by a variety of intestinal virus, with the exception of EV71, also includes Coxsackie virus. These intestinal virus, the current lack of effects of antiviral drugs. Therefore, the general's hand, foot and mouth disease patients, as long as the attention of the appropriate rest, light diet, good oral and skin care, to avoid cross-infection and to give a symptomatic treatment, such as high fever, the proper use of antipyretic drugs, vomiting, diarrhea , Niaoshao be given to appropriate rehydration. After a few days most patients can be cured naturally, without consequences.

A small number of high-risk groups to the development of severe, caused aseptic encephalitis, encephalomyelitis, neurogenic pulmonary edema, pulmonary hemorrhage leading to death or survival after left sequels. The early identification of these patients need. The treatment of these patients mainly concentrated in the immune suppression systemic inflammatory response and targeted treatment.

 

[Shiloh]

Re: China: EV-71 outbreak Kills 43 Children Nationwide, 24,934 Children infected

Source: http://ah.anhuinews.com/system/2008/06/24/002046558.shtml

Google translation:

Anhui news
Hand, Foot and mouth disease control mechanism of science for 42 days without a death case


June 23, journalists from the Provincial Health Office was informed that our province Hand, Foot and Mouth Disease (EV71 infection) epidemic under control, the province's epidemic situation stable, has more than one consecutive month in the lower level of disease control, for 42 days, no deaths Case Report, the province's hand, foot and mouth disease control mechanism of science has been formed.

As of June 22, 24, the day the province reported 128 cases of Hand, Foot and mouth disease, of which 92 cases of in-patients, 83 patients have been discharged from hospital the same day, non-critically ill patients and death cases; province had reported 17,308 cases, 16,104 cases of cure , 390 cases are still hospitalized. Among them, Fuyang City on June 22 a 24-hour report of 33 cases, Bozhou City, 24-hour report, 16 cases are still hospitalized patients were 78 cases and 62 cases.

Through the full implementation of raising the level of treatment of severe cases, the responsibility system for the implementation of packet-depth summer patriotic health campaign to support the key areas where capacity building, policy and other safeguards for medical treatment in patients with effective measures and strengthen supervision and inspection, the establishment of a sound system, vigorously strengthen technology Training, primary health care institutions throughout the province of hand-foot-mouth disease diagnosis and treatment capacity markedly improved, the report further standardize the detection, prevention and control of key sites greatly enhance the management capacity of health, residents markedly improved protection awareness, the province's hand, foot and mouth disease control mechanism of science has been formed.

Provincial Health Office said that the hand, foot and mouth disease is the summer of common infectious diseases, hand, foot and mouth disease control work is a long-term task, the Ministry of Health will continue to adhere to the relevant prevention and control work is not to relax, to protect the health and safety. (Reporter Wang Huihui)
Source: Zhong'an Online - Anhui Daily