tetano
Editor, Senior Moderator
China CDC Wkly
. 2021 Jul 23;3(30):637-644.
doi: 10.46234/ccdcw2021.164.
Long Distance Transmission of SARS-CoV-2 from Contaminated Cold Chain Products to Humans - Qingdao City, Shandong Province, China, September 2020
Huilai Ma[SUP] 1 [/SUP], Zhaoguo Wang[SUP] 2 [/SUP], Xiang Zhao[SUP] 3 [/SUP], Jun Han[SUP] 3 [/SUP], Yong Zhang[SUP] 3 [/SUP], Hong Wang[SUP] 3 [/SUP], Cao Chen[SUP] 3 [/SUP], Ji Wang[SUP] 3 [/SUP], Fachun Jiang[SUP] 2 [/SUP], Jie Lei[SUP] 4 [/SUP], Jingdong Song[SUP] 3 [/SUP], Shaofeng Jiang[SUP] 5 [/SUP], Shuangli Zhu[SUP] 3 [/SUP], Huihui Liu[SUP] 1 [/SUP], Dongyan Wang[SUP] 3 [/SUP], Yao Meng[SUP] 3 [/SUP], Naiying Mao[SUP] 3 [/SUP], Yanhai Wang[SUP] 3 [/SUP], Zhen Zhu[SUP] 3 [/SUP], Zhixiao Chen[SUP] 3 [/SUP], Bingling Wang[SUP] 2 [/SUP], Qinqin Song[SUP] 3 [/SUP], Haijun Du[SUP] 3 [/SUP], Qun Yuan[SUP] 4 [/SUP], Dong Xia[SUP] 3 [/SUP], Zhiqiang Xia[SUP] 3 [/SUP], Peipei Liu[SUP] 3 [/SUP], Yuchao Wu[SUP] 3 [/SUP], Zijian Feng[SUP] 6 [/SUP], Ruqin Gao[SUP] 2 [/SUP], George F Gao[SUP] 6 [/SUP], Wenbo Xu[SUP] 3 [/SUP]
Affiliations
Abstract
What is already known about this topic?
Though coronavirus disease 2019 (COVID-19) has largely been controlled in China, several outbreaks of COVID-19 have occurred from importation of cases or of suspected virus-contaminated products. Though several outbreaks have been traced to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated on the outer packaging of cold chain products, live virus has not been obtained.
What is added by this report?
In September 2020, two dock workers were detected as having asymptomatic SARS-CoV-2 infection using throat swabs during routine screening in Qingdao, China. Epidemiological information showed that the two dock workers were infected after contact with contaminated outer packaging, which was confirmed by genomic sequencing. Compared to the Wuhan reference strain, the sequences from the dock workers and the package materials differed by 12-14 nucleotides. Furthermore, infectious virus from the cold chain products was isolated by cell culture, and typical SARS-CoV-2 particles were observed under electron microscopy.
What are the implications for public health practice?
The international community should pay close attention to SARS-CoV-2 transmission mode through cold chain, build international cooperative efforts in response, share relevant data, and call on all countries to take effective prevention and control measures to prevent virus contamination in cold-chain food production, marine fishing and processing, transportation, and other operations.
Keywords: COVID-19; SARS-CoV-2; cold chain product; genome sequencing; long-distance transmission; virus isolation.
. 2021 Jul 23;3(30):637-644.
doi: 10.46234/ccdcw2021.164.
Long Distance Transmission of SARS-CoV-2 from Contaminated Cold Chain Products to Humans - Qingdao City, Shandong Province, China, September 2020
Huilai Ma[SUP] 1 [/SUP], Zhaoguo Wang[SUP] 2 [/SUP], Xiang Zhao[SUP] 3 [/SUP], Jun Han[SUP] 3 [/SUP], Yong Zhang[SUP] 3 [/SUP], Hong Wang[SUP] 3 [/SUP], Cao Chen[SUP] 3 [/SUP], Ji Wang[SUP] 3 [/SUP], Fachun Jiang[SUP] 2 [/SUP], Jie Lei[SUP] 4 [/SUP], Jingdong Song[SUP] 3 [/SUP], Shaofeng Jiang[SUP] 5 [/SUP], Shuangli Zhu[SUP] 3 [/SUP], Huihui Liu[SUP] 1 [/SUP], Dongyan Wang[SUP] 3 [/SUP], Yao Meng[SUP] 3 [/SUP], Naiying Mao[SUP] 3 [/SUP], Yanhai Wang[SUP] 3 [/SUP], Zhen Zhu[SUP] 3 [/SUP], Zhixiao Chen[SUP] 3 [/SUP], Bingling Wang[SUP] 2 [/SUP], Qinqin Song[SUP] 3 [/SUP], Haijun Du[SUP] 3 [/SUP], Qun Yuan[SUP] 4 [/SUP], Dong Xia[SUP] 3 [/SUP], Zhiqiang Xia[SUP] 3 [/SUP], Peipei Liu[SUP] 3 [/SUP], Yuchao Wu[SUP] 3 [/SUP], Zijian Feng[SUP] 6 [/SUP], Ruqin Gao[SUP] 2 [/SUP], George F Gao[SUP] 6 [/SUP], Wenbo Xu[SUP] 3 [/SUP]
Affiliations
- PMID: 34594958
- PMCID: PMC8393170
- DOI: 10.46234/ccdcw2021.164
Abstract
What is already known about this topic?
Though coronavirus disease 2019 (COVID-19) has largely been controlled in China, several outbreaks of COVID-19 have occurred from importation of cases or of suspected virus-contaminated products. Though several outbreaks have been traced to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated on the outer packaging of cold chain products, live virus has not been obtained.
What is added by this report?
In September 2020, two dock workers were detected as having asymptomatic SARS-CoV-2 infection using throat swabs during routine screening in Qingdao, China. Epidemiological information showed that the two dock workers were infected after contact with contaminated outer packaging, which was confirmed by genomic sequencing. Compared to the Wuhan reference strain, the sequences from the dock workers and the package materials differed by 12-14 nucleotides. Furthermore, infectious virus from the cold chain products was isolated by cell culture, and typical SARS-CoV-2 particles were observed under electron microscopy.
What are the implications for public health practice?
The international community should pay close attention to SARS-CoV-2 transmission mode through cold chain, build international cooperative efforts in response, share relevant data, and call on all countries to take effective prevention and control measures to prevent virus contamination in cold-chain food production, marine fishing and processing, transportation, and other operations.
Keywords: COVID-19; SARS-CoV-2; cold chain product; genome sequencing; long-distance transmission; virus isolation.